Strocit Plus(L)

Introduction About STROCIT PLUS(L)

STROCIT PLUS(L) is a combination of Citicoline and Piracetam which belongs to
the group of medicines called Cerebroactive drugs. It is used as an adjunct for
the management of acute stroke.

Acute stroke can be defined as a brain injury caused due to sudden loss in blood
flow, nutrients and oxygen supply to the brain. It is usually characterized by
paralysis of one side of the body, loss of sensation, double vision, difficulty
in sleeping, facial droop, loss of balance, vertigo, nausea, vomiting, headache
and/or blurred vision.

STROCIT PLUS(L) can also be used to manage memory problems caused due to brain
injury and other age-related brain problems.

Before taking STROCIT PLUS(L) inform your doctor if you have any liver or kidney
problems. You must also inform your doctor if you have any bleeding problems,
history of bleeding in the brain or parkinsonism.

STROCIT PLUS(L) is not recommended for use in patients with Huntington Disease,
intracr
depression. It is also not suitable for use in pregnant or breastfeeding women
unless considered necessary by the physician.

Women of childbearing potential must use a suitable contrace
avoid pregnancy while undergoing therapy with STROCIT PLUS(L).

The most common side effects of taking STROCIT PLUS(L) are headache,
constipation, diarrhea, difficulty in falling asleep, nervousness, dizziness and
weight gain. Consult your doctor if any of these side effects bother you.

Uses Of STROCIT PLUS(L)

It is used to manage:

• Acute stroke
• Memory loss associated with aging or brain injury

How STROCIT PLUS(L) Works

STROCIT PLUS(L) contains two medicines namely citicoline and piracetam.
Citicoline is a neuroprotectant. It protects the nerve cells by blocking the
release of certain chemicals (such as glutamate and other free radicals) within
the brain and nervous system that damages the nerve cells.

Piracetam is a GABA analogue. It improves oxygen supply to the brain and nervous
system and protects it from further injury. Collectively, STROCIT PLUS(L)
repairs the brain cells and regulates proper nerve signal transmissions across
the brain and the nervous system.

How to use STROCIT PLUS(L)

Take STROCIT PLUS(L) as directed by your physician. Swallow the medicine with a
glass of water. Do not crush or chew the medicine.

Your doctor will decide the correct dose and duration of therapy for you
depending upon your age, body weight and disease condition. Do not stop taking
STROCIT PLUS(L) unless your doctor advice you to stop.

Side Effects Of STROCIT PLUS(L)

Common

• weight gain
• headache
• feeling nervous
• muscle spasms
• anxiety or agitation
• numbness, tingling sensation
• constipation, diarrhea, stomach upset
• dizziness
• difficulty in falling asleep
• nausea, vomiting
• skin rash
• back pain, shoulder pain, joint pain

Uncommon

• feeling sad or depressed
• tiredness, weakness

Rare

Stop taking STROCIT PLUS(L) and contact your doctor immediately if you
experience any of the following side effects:

• severe allergic reaction (such as skin rash, swelling of the face, eyelids, lips, tongue or throat which causes difficulty in breathing or swallowing)

How To Manage Side Effects

Nausea:

Take STROCIT PLUS(L) with or just after a meal or a snack. Stick to simple
meals. Avoid eating rich or spicy food. Consult your doctor if your nausea
worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or
machines completely while you are feeling dizzy. Do not consume excessive
alcohol, as it could aggravate your dizziness. Consult your doctor if your
dizziness worsens.

Headache:

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as
water or electrolytes. Applying a pain-relieving balm on your forehead can be
beneficial. Do not consume excessive alcohol, as it could aggravate your
headache. Consult your doctor if your headache worsens.

Constipation:

Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals.
Drink plenty of fluids. Exercise more regularly. Consult your doctor if this
side effect bothers you.

Warning & Precautions

!### Pregnancy

STROCIT PLUS(L) should be used in pregnancy only if it is considered necessary
by the physician. Your doctor will evaluate the risks and benefits of the
therapy and prescribes it to you accordingly. Therefore, inform your doctor
before taking STROCIT PLUS(L) if you are pregnant, think you may be pregnant or
planning to have a baby. Women of childbearing age must use a suitable
contrace
PLUS(L).

!### Breastfeeding

STROCIT PLUS(L) is not recommended for use in breastfeeding women. Therefore,
consult your doctor before taking it.

!### Driving and Using Machines

Do not drive or operate any heavy tools or machines if you experience drowsiness
or shakiness after taking STROCIT PLUS(L).

!### Alcohol

Consum
PLUS(L).

!### Kidney

STROCIT PLUS(L) is not recommended for use in patients who have or ever had any
severe kidney problems. It should be used with caution in patients with other
kidney problems. Therefore, consult your doctor before taking it.

!### Liver

STROCIT PLUS(L) is not recommended for use in patients with severe liver
problems. It should be used with caution in patients with other liver problems.
Therefore, consult your doctor before taking it.

!### Allergy

Do not take STROCIT PLUS(L) if you are allergic to Citicoline or Piracetam.

Others

STROCIT PLUS(L) is not recommended for use if you:

• have a previous history of bleeding in the brain
• have Huntington Disease (a rare genetic disease that causes degeneration of nerve cells)
• have prolonged bleeding within the skull (intracr
• have trimethylaminuria (fishy odor in the urine)
• have Parkinson’s disease
• have a previous history of depression

Before taking STROCIT PLUS(L) inform your doctor if you:

• have any bleeding problems

Use in Pediatrics:

STROCIT PLUS(L) should be used in children and adolescents (aged below 18 years)
only if prescribed by the physician. Therefore, consult your doctor for advice.

Use in Geriatrics:

STROCIT PLUS(L) should be used with caution in elderly patients. Therefore,
consult your doctor before taking it.

Interactions

A. Drug Interactions

Before taking STROCIT PLUS(L) inform to your doctor if you are taking any of the
following medicines such as:

• medicines used to manage thyroid problems (Ex. thyroxine, thyroid extract)
• medicines used for blood thinning (Ex. warfarin)
• aspirin (a medicine used for pain relief)
• levodopa (a medicine used for parkinsonism)
• meclofenoxate (a dietary supplement used to improve memory)

Overdosage:

If you or anyone else accidentally took more STROCIT PLUS(L), consult your
doctor immediately or visit the nearby hospital straight away. Symptoms of
overdosage might include severe headache or severe stomach pain with bloody
diarrhea.

Synopsis

Drug	:	Citicoline, Piracetam
Pharmacological Category	:	Pyrimidine Ribonucleoside diphosphates, GABA analogs
Therapeutic Indication	:	Stroke
Dosage Forms	:	Tablet, Capsule, Syrup

More Information

• Keep STROCIT PLUS(L) out of reach of children
• Store STROCIT PLUS(L) at room temperature

FAQs About STROCIT PLUS(L)

What are the uses of STROCIT PLUS(L)?

STROCIT PLUS(L) is used as an adjunct for the management of acute stroke.

How STROCIT PLUS(L) works?

STROCIT PLUS(L) improves blood flow and oxygen supply to the brain and nervous
system and protects it from further injury. It also repairs the brain cells and
regulates proper nerve signal transmissions across the brain and the nervous
system.

What is the best time to take STROCIT PLUS(L)?

Take STROCIT PLUS(L) as advised by your physician. Your doctor will decide the
best time for you to take STROCIT PLUS(L). Therefore, consult your doctor for
advice.

What are the side effects of taking STROCIT PLUS(L)?

The most common side effects of taking STROCIT PLUS(L) are headache,
constipation, diarrhea, difficulty in falling asleep, nervousness, dizziness and
weight gain. Consult your doctor if any of these side effects bother you.

Can I consume alcohol along with STROCIT PLUS(L)?

It is advisable to avoid alcohol consum
achieve maximum benefits.

Who should not take STROCIT PLUS(L)?

STROCIT PLUS(L) is not recommended for use in patients with severe liver or
kidney problems. It is also not suitable for use in patients with Huntington
Disease, parkinsonism, prolonged bleeding within the skull (intracr
hemorrhage), trimethylaminuria (fishy odor in the urine) or a previous history
of cerebral bleeding or depression. Do not take STROCIT PLUS(L) if you are
pregnant or breastfeeding without consulting your doctor.

What should I do if I forget to take a dose ofSTROCIT PLUS(L)?

If you forget to take a dose of STROCIT PLUS(L), take it as soon as you
remember. However, if it is time to take the next dose of STROCIT PLUS(L), skip
the missed dose and take the next one at regular times. Do not take a double
dose of STROCIT PLUS(L) to compensate the missed dose, as it could lead to
toxicity.

Can I stop taking STROCIT PLUS(L) once my symptom subsides?

Do not stop taking STROCIT PLUS(L) unless your doctor advice you to stop, as
sudden withdrawal of the therapy may cause unpleasant withdrawal symptoms such
as muscle twitching or jerky movements. If you feel better after using STROCIT
PLUS(L), consult your doctor for advice. Your doctor will gradually reduce the
dose before complete cessation of the therapy.

Can STROCIT PLUS(L) be used during pregnancy?

STROCIT PLUS(L) should be used in pregnancy only if it is considered necessary
by the physician. Your doctor will evaluate the risks and benefits of the
therapy and prescribes it to you accordingly.

How to take STROCIT PLUS(L)?

You must take STROCIT PLUS(L) as advised by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine.

Useful Diagnostic Tests

• Activated Partial Thromboplastin Time
• Complete Blood Count
• Prothrombin Time