Sodium Bicarbonate Injection 25ml

Introduction About SODIUM BICARBONATE INJECTION

SODIUM BICARBONATE INJECTION contains Sodium Bicarbonate, which belongs to the
group of medicines called alkalinizing agents. It is used to manage metabolic
acidosis (the correction of the body's acid-alkaline balance), which can occur
in conditions such as severe kidney disease, uncontrolled diabetes, circulatory
insufficiency due to shock or severe dehydration, extracorporeal blood
circulation, cardiac arrest, and drug overdoses such as barbiturates (where
dissociation of the barbiturate-protein complex is desired), salicylate
poisoning, methyl alcohol poisoning, and haemolytic reactions.

It is also used in severe diarrhea, which is often accomp
loss of bicarbonate. Additionally, it will be used to manage patients who have
overused tricyclic antidepressants. It will be used only after the other
resuscitation methods.

SODIUM BICARBONATE INJECTION is not recommended in patients with kidney failure
or kidney stones, high blood pressure,heart failure, shallow or slow breathing
than usual (hypoventilation), any blood abnormalities such as high sodium
levels, low levels of calcium, potassium, or chloride, or if your blood is less
acidic than usual, fluid retention. SODIUM BICARBONATE INJECTION should be used
with caution in patients with liver diseases.

SODIUM BICARBONATE INJECTION should be given to a pregnant woman only if clearly
needed. Contact your doctor before receiving SODIUM BICARBONATE INJECTION should
be used with caution in neonates and children under 2 years of age. Serious side
effects of receiving SODIUM BICARBONATE INJECTION are pain, burning, or swelling
at the site of the injection, extreme irritability, muscle spasms or cramps,
breathing difficulties, low potassium levels, which can cause twitching and
muscle weakness, etc. Consult your doctor if your symptoms get worse or persist.

Uses Of SODIUM BICARBONATE INJECTION

Manage:

• metabolic acidosis (correct the acid-alkaline balance in the body) which can develop in conditions like severe kidney disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal blood circulation, cardiac arrest and in drug overdoses like, salicylate poisoning, methyl alcohol poisoning, etc
• severe diarrhea which is often accomp
• patients who have taken too much tricyclic antidepressant medicine

How SODIUM BICARBONATE INJECTION Works

SODIUM BICARBONATE INJECTION is a systemic alkalizer, which increases plasma
bicarbonate, buffers the excess hydrogen ion concentration, and raises blood pH,
thereby reversing the clinical effects of acidosis.

How to use SODIUM BICARBONATE INJECTION

SODIUM BICARBONATE INJECTION will be given to you only by a doctor or a nurse
into a vein as an intravenous infusion. Your doctor will fix the correct dose
and duration for you depending on your age, body weight, and medical condition.

Side Effects Of SODIUM BICARBONATE INJECTION

Rare

Stop receiving SODIUM BICARBONATE INJECTION and contact your doctor immediately
if you experience any of the following side effects:

• pain, burning or swelling at the site of injection
• extreme irritability
• muscle spasms or cramps
• breathing difficulties
• low potassium levels can cause twitching, muscle weakness, "pins and needles" in the hands or feet, agitation, or an irregular heartbeat
• low blood sugar levels and a high sodium level in the blood can make you feel hunger, thirsty, anxious, confused, extremely irritated, shaky, or sweaty.
• excess acid in the blood, may cause rapid breathing (intracellular acidosis)
• a blood disease that causes an increase in volume of blood flow
• low calcium level may cause involuntary contraction of muscles
• inflammation due to accumulation of fluid under the skin
• bleeding inside the skull may occur in new-borns
• sodium bicarbonate leak out into the surrounding tissue may cause pain, redness, or skin irritation
• if the medication is not injected properly, skin around the injection site may die

Warning & Precautions

!### Pregnancy

SODIUM BICARBONATE INJECTION should be given to a pregnant woman only if clearly
needed. Contact your doctor before receiving SODIUM BICARBONATE INJECTION.

!### Breastfeeding

SODIUM BICARBONATE INJECTION should be given to a breastfeeding woman only if
clearly needed. Contact your doctor before receiving SODIUM BICARBONATE
INJECTION.

!### Driving and Using Machines

SODIUM BICARBONATE INJECTION is unlikely to affect your ability to drive or
operate machines.

!### Kidney

SODIUM BICARBONATE INJECTION is not recommended in patients with kidney failure
or who have had kidney stones. Consult your doctor before receiving SODIUM
BICARBONATE INJECTION.

!### Liver

SODIUM BICARBONATE INJECTION should be used with caution in patients with liver
diseases. Consult your doctor before receiving SODIUM BICARBONATE INJECTION.

!### Allergy

Do not take SODIUM BICARBONATE INJECTION if you are allergic to sodium
bicarbonate or other ingredients of the medicine.

!### Heart Disease

SODIUM BICARBONATE INJECTION is not recommended in patients with high blood
pressure andheart failure. Consult your doctor before receiving SODIUM
BICARBONATE INJECTION.

Others

SODIUM BICARBONATE INJECTION is not recommended if you have:

• breathing is slower or more shallow than usual (hypoventilation)
• any blood abnormalities such as high sodium levels, low levels of calcium, potassium or chloride, or your blood is less acidic than usual
• suffer from fluid retention

Use in pediatrics:

SODIUM BICARBONATE INJECTION should be used with caution neonates and children
under 2 years of age, because it may cause hypernatremia, decrease in
cerebrospinal fluid pressure and possible intracr
doctor before receiving SODIUM BICARBONATE INJECTION.

Use in geriatrics:

SODIUM BICARBONATE INJECTION should be used with caution in elderly patients
aged 65 years or above. Contact your doctor before receiving SODIUM BICARBONATE
INJECTION.

Interactions

A. Drug-Drug interactions:

Before receiving SODIUM BICARBONATE INJECTION, inform your doctor if you are
taking any of the following medicine:

• corticosteroids such as prednisone or corticotropin (medicines used to reduce swelling or to manage hormone problems)
• antibiotics like tetracyclines such as doxycycline (used to manage bacterial infections)
• quinidine, flecainide (medicines used to manage heart problems)
• dobutamine (medicines used to manage cardiogenic shock and heart failure)
• amphetamines (medicines used to manage mental problems and drowsiness)
• ephedrine and pseudoephedrine (medicines used to manage colds and asthma)
• potassium supplements
• parenteral solutions containing calcium
• ethacrynic acid, bumet
• mecamylamine (medicine used to manage high blood pressure)
• memantine (medicine used for Alzheimer’s disease)
• chlorpropamide (medicine used to manage diabetes mellitus)
• lithium, norepinephrine (medicines used to manage mood disorders)
• aspirin (Acetylsalicylic acid) (medicine used to relieve pain, fever, and inflammation)

Overdosage:

If you or anyone else accidentally take too much of SODIUM BICARBONATE
INJECTION, consult your doctor immediately or visit the nearby hospital.
Symptoms of overdose are spasms in the muscles, hands or feet, muscle cramps,
extreme irritability, breathing difficulties, hyperventilation (over breathing),
very sensitive to slight stimuli, twitching and high potassium levels in your
blood may cause dizziness or tiredness.

Synopsis

Drug	:	Sodium Bicarbonate
Pharmacological Category	:	Alkalinising agents
Therapeutic Indication	:	Metabolic acidosis
Dosage Forms	:	Tablet, Injection, Suspension, Drops, Nasal wash, Sachet

More Information

• Keep SODIUM BICARBONATE INJECTION out of reach from children
• Store at room temperature

FAQs About SODIUM BICARBONATE INJECTION

What is SODIUM BICARBONATE INJECTION used for?

SODIUM BICARBONATE INJECTION is used in the management of metabolic acidosis
(correcting the acid-alkaline balance in the body), which can develop in
conditions like severe kidney disease, uncontrolled diabetes, circulatory
insufficiency due to shock or severe dehydration, extracorporeal blood
circulation, cardiac arrest, and in drug overdoses like barbiturates (where
dissociation of the barbiturate-protein complex is desired), salicylate
poisoning, methyl alcohol poisoning, and in haemolytic reactions requiring
alkalinization of the urine to reduce nephrotoxicity of blood pigments, which
require alkalinization of the blood, a metabolitIt is also used in severe
diarrhoea, which is often accomp
Additionally, it can be used to manage patients who have overused tricyclic
antidepressants. It will be used only after the other resuscitation methods.
Contact your doctor before taking SODIUM BICARBONATE INJECTION. Contact your
doctor before taking SODIUM BICARBONATE INJECTION.

Can I use SODIUM BICARBONATE INJECTION during pregnancy?

SODIUM BICARBONATE INJECTION should be given to a pregnant woman only if clearly
needed. Contact your doctor before receiving SODIUM BICARBONATE INJECTION.

Can I use SODIUM BICARBONATE INJECTION with children?

SODIUM BICARBONATE INJECTION should be used with caution in neonates and
children under 2 years of age, because it may cause hypernatremia, a decrease in
cerebrospinal fluid pressure, and possible intracr
your doctor before receiving SODIUM BICARBONATE INJECTION.

How does SODIUM BICARBONATE INJECTION work?

SODIUM BICARBONATE INJECTION is a systemic alkalizer that increases plasma
bicarbonate, buffers the excess hydrogen ion concentration, and raises blood pH,
thereby reversing the clinical effects of acidosis.

Can I use SODIUM BICARBONATE INJECTION while breast-feeding?

SODIUM BICARBONATE INJECTION should be given to a breastfeeding woman only if
clearly needed. Contact your doctor before receiving SODIUM BICARBONATE
INJECTION.