Senacept 60mg Tablet 10'S

Introduction About SENACEPT 60MG TABLET

SENACEPT 60MG TABLET contains Cinacalcet which belongs to a group of medicines
called Calcimimetic agent that increases the sensitivity of the calcium-sensing
receptor to activation by extracellular calcium. It is used for secondary
hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) on
dialysis and for hypercalcemia in patients with parathyroid outgrowth.

Hyperparathyroidism (HPT) is a condition where the parathyroid gland may become
overactive and make too much PTH. In this condition the calcium stored in the
bones move into the blood leading to hypercalcemia (too much calcium in the
blood). Secondary hyperparathyroidism (SHPT) describes an alteration in bone and
mineral metabolism that occurs as a direct result of chronic kidney disease
(CKD). The parathyroid gland is the central organ responsible for regulating
these ada
hormone helps in low calcium levels by acting on the bones, intestine,
and kidneys. SENACEPT 60MG TABLET works by controlling levels of the parathyroid
hormone (PTH), calcium and phosphorous in body.

Do not drive or operate machines, if you experience side effects such as
dizziness and seizures while taking this medicine. If you are pregnant or
breast-feeding, think you may be pregnant or planning to have a baby, ask your
doctor for advice before taking this medicine. The most common side effects are
nausea, vomiting, dizziness, rash, muscle pain, loss of appetite, headache.
Consult your doctor if you experience any of the above side effects persists for
a longer duration.

Uses Of SENACEPT 60MG TABLET

It is used for:

• secondary hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) on dialysis
• hypercalcemia in patients with parathyroid outgrowth

How SENACEPT 60MG TABLET Works

SENACEPT 60MG TABLET works by controlling levels of the parathyroid hormone
(PTH), calcium and phosphorous in body.

How to use SENACEPT 60MG TABLET

Always take this medicine as advised by the physician. Swallow the medicine with
a glass of water. Do not crush or chew the medicine. Your doctor will decide the
correct dose and duration of therapy for you depending upon your age, body
weight and disease condition. Do not stop taking SENACEPT 60MG TABLET unless
your doctor advice you to stop.

Side Effects Of SENACEPT 60MG TABLET

Common

• dizziness
• headache
• nausea or vomiting
• constipation
• feeling weak
• loss (anorexia) or decrease of appetite
• muscle pain
• weakness
• rash
• high potassium levels in the blood (hyperkalaemia)
• allergic reactions
• diarrhea
• indigestion

Stop taking SENACEPT 60MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• numbness or tingling around mouth, muscle aches or cramps and seizures. these may be signs of low calcium levels (hypocalcaemia)
• swelling of face, lips, mouth, tongue or throat which may cause by difficulty in swallowing or breathing (angioedema)

How To Manage Side Effects

!### Constipation

Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink
plenty of water. Exercise more regularly.

Headache

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room.
Drink tea or coffee.

!### Nausea And Vomiting

Keep taking this medicine with, or just after, a meal or snack and stick to
simple meals and do not eat rich or spicy food.

Warning & Precautions

!### Pregnancy

Consult your doctorSENACEPT 60MG TABLET should be used during pregnancy only if the potential
benefit justifies the potential risk to the fetus. Consult your doctor before
taking it.

!### Breastfeeding

Consult your doctorIt is not known whether SENACEPT 60MG TABLET is excreted in human milk.
Therefore, consult your doctor before taking the medicine.

!### Driving and Using Machines

ContraindicatedDo not drive or operate any machinery while taking this medicine, it may make
you feel dizziness.

!### Alcohol

ContraindicatedConsum

!### Kidney

Use with CautionSENACEPT 60MG TABLET should be taken with caution in patients with severe kidney
disease. Consult your doctor for advice.

Liver

Use with CautionSENACEPT 60MG TABLET should be taken with caution in patients with severe liver
disease. Consult your doctor for advice.

!### Allergy

ContraindicatedDo not take SENACEPT 60MG TABLET if you are allergic to any of its ingredients
of this medicine.

!### Heart Disease

Use with CautionSENACEPT 60MG TABLET should be taken with caution in patients with cardiac
problems. Consult your doctor for advice.

!### Use In Pediatrics

Consult your doctorThe safety and efficacy of SENACEPT 60MG TABLET in pediatric patients have not
been established.

!### Use In Geriatrics

Use with CautionSENACEPT 60MG TABLET should be used with caution in elderly patients above 65
years of age. Consult your doctor for advice.

Others

It is not recommended SENACEPT 60MG TABLET if you have low levels of calcium in
your blood

Interactions

A. Drug - Drug Interactions:

Before taking SENACEPT 60MG TABLET, inform your doctor if you are taking any of
the following medicines:

• medicines used for skin and fungal infections
• medicines used for bacterial infections (telithromycin, rifampicin and ciprofloxacin)
• medicines used for viral infection (ritonavir)
• medicines used to manage depression (fluvoxamine)
• medicines used to relieve cough (dextromethorphan)
• medicines used for changes in heart rate (flecainide and propafenone)
• medicines used to manage high blood pressure

B. Drug - Food Interaction:

• It is advised to take SENACEPT 60MG TABLET with food or shortly after a meal.

Overdosage:

• If you or anyone else accidentally took more SENACEPT 60MG TABLET, consult your doctor immediately or visit your nearby hospital. Symptoms of overdosage is hypocalcemia.

Synopsis

Drug	:	Cinacalcet
Pharmacological Category	:	Calcimimetics
Therapeutic Indication	:	Hyperparathyroidism
Dosage Forms	:	Tablet

More Information

• Keep SENACEPT 60MG TABLET out of reach of children
• Store SENACEPT 60MG TABLET at room temperature

FAQs About SENACEPT 60MG TABLET

Q: Can SENACEPT 60MG TABLET be used in pregnant women?

A: No. It is not recommended for use in the pregnant women. Consult your doctor
before taking.

Q: How and when to take SENACEPT 60MG TABLET?

A: Take SENACEPT 60MG TABLET preferably after meals or as advised by your
physician. Swallow the medicine with a glass of water. Do not cursh or chew the
medicine. Your doctor will decide the correct dose and duration of therapy for
you depending upon your age, body weight and disease condition.

Q: How long should I take SENACEPT 60MG TABLET?

A: You need to take SENACEPT 60MG TABLET as long as your doctor or physician
prescribes you the medicine. Your doctor will decide the correct dose and
duration of therapy for you depending upon your age, body weight and disease
condition

Q: What is the best time to take SENACEPT 60MG TABLET?

A: SENACEPT 60MG TABLET must be taken after meals to avoid gastrointestinal side
effects. Consult your doctor for advice.

Q: What to do if I forgot to take a dose of SENACEPT 60MG TABLET?

A: If you forgot to take a dose of SENACEPT 60MG TABLET, take it as soon as you
remember. However, if it is time for the next dose of SENACEPT 60MG TABLET, skip
the missed dose and take the next one regularly. Do not take a double dose of
SENACEPT 60MG TABLET to compensate the missed ones.

Q: What are the most common side effects of taking SENACEPT 60MG TABLET?

A: The most common side effects of SENACEPT 60MG TABLET are nausea, vomiting,
dizziness, rash, muscle pain, loss of appetite, headache. Consult your doctor if
you experience any of the above side effects persists for a longer duration.

Q: Can I stop taking SENACEPT 60MG TABLET without consulting your doctor?

A: No. You should not stop taking SENACEPT 60MG TABLET without consulting your
doctor because it may lead to reversal of symptoms. If you feel better after
using SENACEPT 60MG TABLET, consult your doctor for advice.

Useful Diagnostic Tests

• Thyroid Stimulating Hormone (TSH)
• Urine Routine & Microscopy
• Kidney Function Test (KFT)
• Thyroid Profile -Total (T3,T4&Tsh)
• Thyroid Profile- Free (Ft3, Ft4 & Tsh)
• Creatinine, Serum
• Uric Acid, Serum
• Albumin, Serum