Restasis 0.05% Ophthalmic Solution 30X0.4ml

Introduction About RESTASIS 0.05% OPTHALMIC SOLUTION

RESTASIS 0.05% OPTHALMIC SOLUTION contains Cyclosporin which belongs to the
group of medicines called Immunosuppressants.  It is used to manage severe dry
eye syndrome (keratoconjunctivitis sicca) in children and in adolescents (aged
between 4-18 years).

Dry Eye Syndrome (also known as keratoconjunctivitis sicca) is an allergic eye
condition that affects the transparent layer in the front part of the eye and
the thin membrane covering the front part of the eye. It is characterized by
excessive eye dryness, redness, itching, inflammation and discomfort. Persons
having dry eye syndrome do not produce sufficient tears to lubricate and nourish
the eyes.

RESTASIS 0.05% OPTHALMIC SOLUTION is for ophthalmic use only. Wash your hands
before and after application. Avoid touching the tip of the container with your
mouth, nose or other parts of body to avoid contamination.

If you wear soft contact lenses, make sure to remove them before using RESTASIS
0.05% OPTHALMIC SOLUTION. Consult your doctor about the usage of contact lenses
while undergoing management for dry eyes.

Before using RESTASIS 0.05% OPTHALMIC SOLUTION inform your doctor if you have
any other eye conditions apart from dry eye syndrome such as eye infection or
glaucoma. RESTASIS 0.05% OPTHALMIC SOLUTION is not recommended for use in
patients having cancer in and around the eye areas. Consult your doctor before
using RESTASIS 0.05% OPTHALMIC SOLUTION if you are pregnant or breastfeeding.

The most common side effects of using RESTASIS 0.05% OPTHALMIC SOLUTION are eye
pain, redness, irritation or discomfort, watery eyes and blurred vision. Consult
your doctor if they trouble you.

Uses Of RESTASIS 0.05% OPTHALMIC SOLUTION

• Manage severe dry eye syndrome

How RESTASIS 0.05% OPTHALMIC SOLUTION Works

RESTASIS 0.05% OPTHALMIC SOLUTION is an immunosuppressive agent. Following
application on the eyes, it blocks the release of certain chemicals in the eye
(such as T-cells, interleukins and cytokines) that causes eye inflammation,
allergies and discomfort. As a result, it reduces inflammation and swelling on
the eye and keeps your eyes lubricated by allowing your eye to produce tears.

How to use RESTASIS 0.05% OPTHALMIC SOLUTION

Use RESTASIS 0.05% OPTHALMIC SOLUTION as advised by your physician. It is for
ophthalmic use only. Wash your hands before application. Tilt your head slightly
backwards and place the tip of the container close to your eyes.

Gently pull your lower eyelid and instil few drops of the medicine as directed
by your physician. Close your eyes and gently press the inner corner of your eye
for 2 minutes. Repeat the same for the other eye if required.

Do not touch the tip of the container with your eyes, eyelids or areas around
your eyes or fingers, to avoid contamination. Avoid wearing contact lenses while
undergoing therapy for dry eyes.

Your doctor will decide the correct dose and duration of therapy for you
depending upon your age, body weight and disease condition. Do not stop using
RESTASIS 0.05% OPTHALMIC SOLUTION unless your doctor tells you to stop.

Side Effects Of RESTASIS 0.05% OPTHALMIC SOLUTION

Common

• Eye pain, redness, irritation or discomfort
• Sensation of foreign body in the eye
• Increased watering of eyes
• Blurred vision
• Swelling and redness of eyelids
• Upper respiratory tract
• Cough, headache

How To Manage Side Effects

Eye irritation, redness or discomfort:

Avoid watching direct light sources. Do not strain your eyes too much. Protect
your eyes from bright light while going outdoors using sunglasses. Consult your
doctor if this side effect bothers you.

Blurred vision:

Close your eyes and relax. Do not strain your eyes by looking at mobile phones,
laptops, or television. Avoid driving or operating any heavy tools or machines
while your vision is blur. Consult your doctor if you experience blurred vision
for a prolonged period.

Warning & Precautions

!### Pregnancy

RESTASIS 0.05% OPTHALMIC SOLUTION is not recommended for use in pregnant women.
Therefore, consult your doctor before using it. Women of childbearing potential
should use suitable contrace
with RESTASIS 0.05% OPTHALMIC SOLUTION.

!### Breastfeeding

RESTASIS 0.05% OPTHALMIC SOLUTION should be used with caution in breast-feeding
women. Therefore, consult your doctor before using it.

!### Driving and Using Machines

RESTASIS 0.05% OPTHALMIC SOLUTION may temporarily blur your vision. Therefore,
do not drive or handle any heavy tools or machines if you experience blurred
vision after applying RESTASIS 0.05% OPTHALMIC SOLUTION.

!### Alcohol

Consum
OPTHALMIC SOLUTION.

!### Allergy

Do not use RESTASIS 0.05% OPTHALMIC SOLUTION if you are allergic to cyclosporin.

Others

RESTASIS 0.05% OPTHALMIC SOLUTION is not recommended for use if you:

• have or ever had cancer in or around eyes
• have an eye infection

Before using RESTASIS 0.05% OPTHALMIC SOLUTION inform your doctor if you:

• had an eye infection (herpes viral infection) or suspect of having it
• have any other eye problems (such as glaucoma)

Use in paediatrics:

RESTASIS 0.05% OPTHALMIC SOLUTION is not recommended for use in children (aged
below 4 years). Therefore, consult your doctor before using it.

Interactions

A. Drug - Drug interactions:

Before using RESTASIS 0.05% OPTHALMIC SOLUTION, inform your doctor if you are
taking any of the following medicine:

• eye drops containing steroids (Ex. dexamethasone)
• medicines used to manage glaucoma (Ex. latanoprost, travoprost, tafluprost, bimatoprost)

Overdosage:

If you or anyone else accidentally used excessive amount of RESTASIS 0.05%
OPTHALMIC SOLUTION, rinse your eyes with plain water to ease the irritation. If
you irritation persists, consult your doctor.

Synopsis

Drug	:	Cyclosporin
Pharmacological Category	:	Calcineurin Inhibitors
Therapeutic Indication	:	Dry Eye Syndrome
Dosage Forms	:	Tablet, capsule, Injection, Infusion, Oral Solution, Oral Suspension, Eye Drops, Ophthalmic Emulsion

More Information

• Keep RESTASIS 0.05% OPTHALMIC SOLUTION out of reach of children
• Store RESTASIS 0.05% OPTHALMIC SOLUTION at room temperature

FAQs About RESTASIS 0.05% OPTHALMIC SOLUTION

What is the use of RESTASIS 0.05% OPTHALMIC SOLUTION?

RESTASIS 0.05% OPTHALMIC SOLUTION is used to manage severe dry eye syndrome
(keratoconjunctivitis sicca) in children and in adolescents (aged between 4-18
years).

How RESTASIS 0.05% OPTHALMIC SOLUTION works?

RESTASIS 0.05% OPTHALMIC SOLUTION is an immunosuppressive agent. Following
application on the eyes, it blocks the release of certain chemicals in the eye
(such as T-cells, interleukins and cytokines) that causes eye inflammation,
allergies and discomfort. As a result, it reduces inflammation and swelling on
the eye and keeps your eyes lubricated by allowing your eye to produce tears.

How to take RESTASIS 0.05% OPTHALMIC SOLUTION?

Wash your hands before application. Tilt your head slightly backwards and place
the tip of the container close to your eyes. Gently pull your lower eyelid and
instil few drops of the medicine as directed by your physician. Close your eyes
and gently press the inner corner of your eye for 2 minutes. Repeat the same for
the other eye if required.

How long should I use RESTASIS 0.05% OPTHALMIC SOLUTION?

You need to use RESTASIS 0.05% OPTHALMIC SOLUTION for the stipulated duration
prescribed by your doctor. Your doctor will decide the correct dose and duration
of therapy for you depending upon your age, body weight and disease condition.

Is RESTASIS 0.05% OPTHALMIC SOLUTION safe?

RESTASIS 0.05% OPTHALMIC SOLUTION is safe at doses prescribed by the physician.
Therefore, do not alter the dose of RESTASIS 0.05% OPTHALMIC SOLUTION without
consulting your doctor.

Can I stop using RESTASIS 0.05% OPTHALMIC SOLUTION without consulting your
doctor?

No. You should not stop using RESTASIS 0.05% OPTHALMIC SOLUTION without
consulting your doctor as it may cause the symptoms to re-appear. Therefore, use
RESTASIS 0.05% OPTHALMIC SOLUTION for the stipulated duration recommended by
your doctor to achieve maximum results.

Will using a higher dose of RESTASIS 0.05% OPTHALMIC SOLUTION be more
effective?

No, using a higher dose of RESTASIS 0.05% OPTHALMIC SOLUTION will not be
effective rather it can lead to toxicity. Always apply the dose prescribed by
your doctor. If the prescribed dose is not effective for you, consult your
doctor for advice. Your doctor might increase the dose or suggest an alternative
therapy.

Can RESTASIS 0.05% OPTHALMIC SOLUTION be used in pregnant women?

RESTASIS 0.05% OPTHALMIC SOLUTION is not recommended for use in pregnant women
unless considered necessary by the physician. Therefore, consult your doctor
before using it.

What are the common side effects of using RESTASIS 0.05% OPTHALMIC SOLUTION?

The most common side effects of using RESTASIS 0.05% OPTHALMIC SOLUTION are eye
pain, redness, irritation or discomfort, watery eyes and blurred vision. Consult
your doctor if they trouble you.

What to do if I forgot to apply RESTASIS 0.05% OPTHALMIC SOLUTION?

If you forgot to apply a dose of RESTASIS 0.05% OPTHALMIC SOLUTION, apply it as
soon as you remember. However, if it is time for the next dose of RESTASIS 0.05%
OPTHALMIC SOLUTION, skip the missed dose and apply the next one regularly. Do
not apply a double dose of RESTASIS 0.05% OPTHALMIC SOLUTION to compensate the
missed ones.

How long will it take for RESTASIS 0.05% OPTHALMIC SOLUTION to heal my
condition?

You need to apply RESTASIS 0.05% OPTHALMIC SOLUTION as long as your doctor
prescribes you the medicine. Your doctor will decide the correct dose and
duration of therapy for you depending upon your age, body weight and disease
condition.

Can I use other eye medicines while using RESTASIS 0.05% OPTHALMIC SOLUTION?

Avoid using any other eye medicines along with RESTASIS 0.05% OPTHALMIC SOLUTION
without consulting your doctor as it may increase the risk of side effects.

Can RESTASIS 0.05% OPTHALMIC SOLUTION reduce conjunctivitis?

Yes. RESTASIS 0.05% OPTHALMIC SOLUTION can be used to manage allergic eye
conditions (such as allergic conjunctivitis, keratoconjunctivitis, etc.).

Can the use of RESTASIS 0.05% OPTHALMIC SOLUTION cause blurred vision?

Yes. RESTASIS 0.05% OPTHALMIC SOLUTION may cause blurred vision after
application. If your vision becomes blur, close your eyes for some time and
rest. Do not strain your eyes by looking at mobile phones, laptops, or
television. Avoid driving or operating any heavy tools or machines while your
vision is blur. Consult your doctor if you experience blurred vision for a
prolonged period.