Pirox 20mg Injection 1ml

Introduction About PIROX 20MG INJECTION

PIROX 20MG INJECTION contains Piroxicam, which belongs to the group of medicines
called Non-Steroidal Anti-Inflammatory Drugs. It is used in the management of
musculoskeletal disorders (injuries or disorders of muscle, ligaments, joints,
and tendons characterised by pain, stiffness, swelling, and restricted
movements), acute gout (a form of arthritis with severe pain, redness, and
tenderness in joints), postoperative trauma pain (pain due to trauma after
surgical intervention), and primary dysmenorrhea (sudden cramping pain in the
lower abdomen occurring before or during menstruation).

PIROX 20MG INJECTION exerts its anti-inflammatory actions by inhibiting the
enzyme cyclooxygenase-1, thereby, blocking the release of prostaglandins (a
substance produced during injury and inflammation that causes pain and swelling)
and other chemical mediators that cause pain and swelling. Your doctor may
advise you to take relevant tests before recommending this medicine.

PIROX 20MG INJECTION is not recommended for use in patients with liver, kidney,
or heart problems. PIROX 20MG INJECTION is not recommended for use by a pregnant
or breastfeeding woman. It should be used with caution in children aged 12 years
and older. The most common side effects by receiving this medicine are nausea
(feeling sick), vomiting, and stomach pain. Contact your doctor if your symptom
does not improve.

Uses Of PIROX 20MG INJECTION

• Management of musculoskeletal disorders, acute gout, postoperative trauma pain, and primary dysmenorrhea from 12 years of age or older

How PIROX 20MG INJECTION Works

PIROX 20MG INJECTION exerts its anti-inflammatory actions by inhibiting the
enzyme cyclooxygenase-1 thereby, blocking the release of prostaglandins (a
substance produced during injury and inflammation causing pain and swelling) and
other chemical mediators that cause pain and swelling.

How to use PIROX 20MG INJECTION

PIROX 20MG INJECTION will be administered by your doctor or nurse by injection
into a muscle (intramuscular). Your healthcare provider will administer the
right dose depending on your health condition.

Side Effects Of PIROX 20MG INJECTION

Common

• signs of gastric perforation and ulceration like burning sensation, severe stomach pain
• signs of pancreatitis include tenderness, vomiting, upper abdominal pain
• gastrointestinal bleeding (including hematemesis vomiting blood, melena (blood in stools or faeces)
• gastritis, epigastric distress (upper abdominal pain)
• nausea (feeling sick)
• constipation
• abdominal discomfort
• flatulence
• abdominal pain
• diarrhoea
• vomiting
• indigestion
• stomatitis (painful mouth ulcers)

How To Manage Side Effects

Nausea or vomiting:

Take this medicine with meals or just after meals. Stick to simple meals. Try to
avoid oil-rich or spicy foods, sugary snacks, and drinks. Try to drink liquids
slowly along with your meals or in between meals. Consult your doctor if your
symptom is not improving.

Stomach pain:

Try to rest and relax. Try to have smaller and more frequent meals. Keep a
heating pad on your stomach. Take your physician’s advice.

Warning & Precautions

!### Pregnancy

PIROX 20MG INJECTION is not recommended for use by pregnant women. Consult your
doctor before receiving this medicine.

!### Breastfeeding

PIROX 20MG INJECTION is not recommended for use by breastfeeding women as it may
pass to the baby through breast milk. Discuss the risks and benefits with your
doctor.

!### Driving and Using Machines

The effect of PIROX 20MG INJECTION on the ability to drive or operate machinery
has not been studied.

!### Kidney

PIROX 20MG INJECTION is not recommended for use in patients with severe kidney
disease. Consult your doctor for advice.

!### Liver

PIROX 20MG INJECTION is not recommended for use in patients with severe liver
disease. Consult your doctor for advice.

!### Allergy

Do not receive PIROX 20MG INJECTION if you are allergic to Piroxicam.

!### Heart Disease

PIROX 20MG INJECTION is not recommended for use in patients with severe heart
failure. It should be taken with caution in patients having high blood pressure,
and fluid retention. Consult your doctor for advice.

Others

PIROX 20MG INJECTION is not recommended for use if you:

• have stomach or intestinal ulcer, bleeding, or perforation
• have peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery

Before receiving PIROX 20MG INJECTION, inform your doctor if you:

• have dehydration

Use in pediatrics:

PIROX 20MG INJECTION should be used with caution in children aged 12 years of
age and above. Consult your doctor for advice.

Interactions

A.Drug-Drug interactions:

• aspirin, acetylsalicylic acid or other non-steroidal anti-inflammatory drugs for pain relief
• anticoagulants such as warfarin, and heparin (a medicine used to manage blood clots)
• corticosteroids like prednisolone (medicines used to manage a variety of conditions such as allergies and hormone imbalance)
• lithium (a medicine used to manage some mental problems)
• methotrexate (a medicine used for the management of some inflammatory diseases and some cancers)
• ciclosporin and tacrolimus (a medicine used to manage some inflammatory diseases and after transplants)
• cardiac glycosides (Ex. digoxin) used to manage heart problems
• cimetidine (a medicine used to manage stomach ulcers)
• antacids for indigestion and heartburn (ex. calcium carbonate, aluminium hydroxide)
• losartan, valsartan, ramipril, enalapril, furosemide, propranolol, atenolol (medicines used to manage high blood pressure)
• cholestyramine (a medicine used to lower blood cholesterol levels)

Overdosage:

If you or anyone else accidentally received too much of PIROX 20MG INJECTION,
consult your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Piroxicam
Pharmacological Category	:	Non-steroidal anti-inflammatory drugs
Therapeutic Indication	:	Reduce joint pain
Dosage Forms	:	Tablet, Capsule, Dispersible tablet, Gel, Injection

More Information

• Keep PIROX 20MG INJECTION out of reach from children
• Store away from warm temperatures and light

FAQs About PIROX 20MG INJECTION

What are the uses of PIROX 20MG INJECTION?

PIROX 20MG INJECTION is indicated in the management of musculoskeletal
disorders, acute gout, postoperative trauma pain, and primary dysmenorrhea (12
years of age or older).

How does PIROX 20MG INJECTION work?

PIROX 20MG INJECTION exerts its anti-inflammatory actions by inhibiting the
enzyme cyclooxygenase-1, thereby blocking the release of prostaglandins (a
substance produced during injury and inflammation that causes pain and swelling)
and other chemical mediators that cause pain and swelling.

Can PIROX 20MG INJECTION be used in patients with heart problems?

PIROX 20MG INJECTION is not recommended for use in patients with severe heart
failure. It should be used with caution in patients with high blood pressure and
fluid retention. Consult your doctor for advice.

Can PIROX 20MG INJECTION be used by a pregnant woman?

PIROX 20MG INJECTION or other painkiller medicines (NSAIDs) are not recommended
for use in pregnancy. Consult your doctor for advice before receiving
[GBNKEYEORD].

Can PIROX 20MG INJECTION be given to children?

PIROX 20MG INJECTION should be used with caution in children 12 years of age and
older. The correct dose and duration will be determined by your doctor based on
your age and body weight. Consult your doctor for advice.