Perinorm MD 10mg Tablet 10'S

Introduction About PERINORM MD 10MG TABLET

PERINORM MD 10MG TABLET contains Metoclopramide which belongs to the group of
medicines called Anti-emetics. It is used to manage nausea and vomiting which
may occur after chemotherapy or radiotherapy. It can also be used to manage
nausea and vomiting which occurs because of migraine. Migraine is a headache
which causes severe throbbing pain or pulsing sensation particularly on one side
of the head and it is characterized by symptoms such as nausea, vomiting and
sensitivity to light.

Before taking PERINORM MD 10MG TABLET, inform your doctor if you are having
liver, kidney or heart diseases, porphyria (rare blood disorder), brain problems
or if you are taking any other medicines that may affect your heartbeat. Avoid
consum
the risk of sedative effects.

Your doctor may perform blood tests during the management to monitor your blood
pigment (haemoglobin) levels. Your doctor may immediately or permanently stop
your management if there are any abnormalities in the levels of blood pigment.

PERINORM MD 10MG TABLET is not recommended for use in patients with epilepsy,
parkinson’s disease, bleeding, obstruction or tear in the stomach or gut, tumour
of adrenal gland and involuntary muscle spasms. PERINORM MD 10MG TABLET should
be used with caution in pregnant women only if clearly advised by the doctor and
it is not recommended for use in breastfeeding women as it may pass through the
breast milk.

PERINORM MD 10MG TABLET is not recommended for use in children (below 1 year of
age) and it should be used with caution in elderly patients. Consult your doctor
before taking it. The most common side effects of taking PERINORM MD 10MG TABLET
are drowsiness, restlessness, feeling weak uncontrollable body movements (such
as muscle stiffness or rigidity) and diarrhoea. Consult your physician
immediately if any of these side effects worsens.

Uses Of PERINORM MD 10MG TABLET

• Prevents nausea and vomiting due to chemotherapy or radiotherapy
• Manage nausea and vomiting (including migraine)

How PERINORM MD 10MG TABLET Works

PERINORM MD 10MG TABLET acts and supresses certain centres called dopamine
(brain chemical) centres by decreasing the sensitivity of the nerves that
transmit signals from gastrointestinal tract to the vomiting centres in the
brain. It also relaxes the muscles of stomach and enhances the motility of gut
and manages nausea and vomiting.

How to use PERINORM MD 10MG TABLET

Take PERINORM MD 10MG TABLET as advised by your physician. Swallow PERINORM MD
10MG TABLET with a glass of water. Do not crush or chew the medicine. Your
doctor will determine the exact dose and duration for you depending upon your
age, body weight and disease condition.

Side Effects Of PERINORM MD 10MG TABLET

Common

• drowsiness
• uncontrollable movements of body (such as shaking, tics, twisting movements or muscle stiffness or rigidity)
• rigidity and tremor (similar to Parkinson’s disease)
• restlessness
• diarrhoea
• feeling weak

Uncommon

• elevated levels of hormone called prolactin (which cause milk secretion in men and women who are not breastfeeding)
• irregular periods
• hallucinations
• decreased consciousness
• allergy
• visual problems such as involuntary deviation of eyeball

Rare

• confusion
• convulsions (fits) especially in patients with history of epilepsy (seizures)

Stop taking PERINORM MD 10MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• uncontrollable movements of head and neck (occurs in children or young adults)
• signs of a brain disorder called neurole
• signs of severe allergic reactions (such as itching, skin rashes, swelling of the face, lips and throat, breathing difficulties)

How To Manage Side Effects

Diarrhoea:

Drink lot of fluids, such as water or fruit juice to keep yourself hydrated.
Avoid eating high-fat or spicy foods. Do not take any medicine on your own to
manage diarrhea without consulting your doctor.

Feeling weak:

Drink plenty of fluid and eat balanced diet and frequent meals. Do regular
minimal exercise (such as walking) and follow regular sleep schedule. Consult
your doctor if the symptom does not improve.

Warning & Precautions

!### Pregnancy

PERINORM MD 10MG TABLET should be used with caution during pregnancy only if
clearly advised by your doctor. Consult your doctor before taking it.

!### Breastfeeding

PERINORM MD 10MG TABLET is not recommended for use in breastfeeding women as it
may pass through the breast milk and affect your baby. Consult your doctor
before taking it.

!### Driving and Using Machines

Do not drive or operate any machines if you feel dizzy, drowsy or have
uncontrollable twitching, jerking or writhing movements and unusual muscle tone
leading to distortion of the body or your vision gets affected after taking
PERINORM MD 10MG TABLET.

!### Alcohol

Avoid consum
increase the sedative effects.

!### Kidney

PERINORM MD 10MG TABLET should be taken with caution in patients with moderate
or severe kidney disease. Consult your doctor before taking it.

!### Liver

PERINORM MD 10MG TABLET should be taken with caution in patients with severe
liver problems. Consult your doctor before taking it.

!### Allergy

Do not take PERINORM MD 10MG TABLET if you are allergic to Metoclopramide.

!### Heart Disease

PERINORM MD 10MG TABLET should be taken with caution in patients having heart
diseases such as abnormal heartbeats or any other heart problems. Consult your
doctor before taking it.

Others

PERINORM MD 10MG TABLET is not recommended for use if you:

• have bleeding, obstruction or a tear in your stomach or gut
• have or may have a rare tumour of adrenal gland called pheochromocytoma
• had involuntary muscle spasms
• have epilepsy (seizures or fits)
• have brain disorder called parkinson’s disease
• had gastrointestinal surgery in the last 3 to 4 days
• had abnormal levels of blood pigments (methemoglobinemia or NADH cytochrome b5 deficiency)

Before taking PERINORM MD 10MG TABLET, inform your doctor if you:

• have problems with the salts in the blood such as potassium, sodium or magnesium
• have any brain problems
• have a history of immune problem called atopy (including asthma)
• have porphyria (rare inherited blood disorder)

Use in paediatrics:

PERINORM MD 10MG TABLET is not recommended for use in children (below 1 year of
age) because of increased risk of uncontrollable movements. It should be used
with caution in children and adolescents aged between (15-18 years of age).
 Consult your child’s doctor for advice.

Use in geriatrics:

PERINORM MD 10MG TABLET should be used with caution in elderly patients and your
doctor may adjust the dose depending upon kidney or liver problems and overall
health condition. Consult your doctor before taking it.

Interactions

A. Drug-Drug interactions:

Before taking PERINORM MD 10MG TABLET, inform your doctor if you are taking any
of the following medicines:

• medicines used to manage a brain disorder called parkinson’s disease (Ex. levodopa, carbidopa)
• anticholinergics (medicines used to manage stomach cramps and spasms) Ex. dicyclomine, hyoscyamine
• morphine derivatives (medicine used to manage severe pain) Ex. oxycodone, oxymorphone
• sedative medicines (used to manage sleeping disorders, anxiety or p
• medicines used to manage mental problems (Ex. quetiapine, risperidone)
• digoxin (used to manage heart failure)
• ciclosporin (used to manage immune problems)
• mivacurium and suxamethonium (medicines used to relax the muscles)
• atovaquone (used to manage pneumonia)
• fluoxetine and paroxetine (used to manage depression)

Overdosage:

If you or anyone else accidentally take too much of PERINORM MD 10MG TABLET,
consult your doctor immediately or visit the nearby hospital. Symptoms of
overdose are uncontrollable movements, feeling drowsy, impaired consciousness,
confusion, hallucinations and heart problems.

Synopsis

Drug	:	Metoclopramide
Pharmacological Category	:	Anti-emetics
Therapeutic Indication	:	Nausea and Vomiting
Dosage Forms	:	Tablet, Capsule, Syrup, Injection

More Information

• Keep PERINORM MD 10MG TABLET out of reach of children
• Store PERINORM MD 10MG TABLET at room temperature

FAQs About PERINORM MD 10MG TABLET

What are the common side effects of [GBNKWYWORD]?

The most common side effects of taking PERINORM MD 10MG TABLET are drowsiness,
uncontrollable movements of body (such as shaking, tics, twisting movements or
muscle stiffness or rigidity), tremor and rigidity similar to parkinson’s
disease, restlessness, diarrhoea and feeling weak. Consult your doctor
immediately if you experience any of these side-effects.

Is PERINORM MD 10MG TABLET safe to use in children?

PERINORM MD 10MG TABLET is not recommended for use in children (below 1 year of
age) because of the increased risk of uncontrollable movements. It should be
used with caution in children and adolescents aged between (15 to 18 years of
age). Consult your child’s doctor for advice before giving PERINORM MD 10MG
TABLET to your child.

CanPERINORM MD 10MG TABLET be used in patients with kidney disease?

PERINORM MD 10MG TABLET should be used with caution in patients with moderate or
severe kidney disease. Your doctor may adjust the dose depending upon kidney
function. Consult your doctor before taking it.

IsPERINORM MD 10MG TABLET safe to use during pregnancy?

PERINORM MD 10MG TABLET should be used with caution during pregnancy only if
clearly advised by your doctor. Consult your doctor before taking PERINORM MD
10MG TABLET if you are pregnant or planning to get pregnant.

Can I drive or operate machines after takingPERINORM MD 10MG TABLET?

Do not drive or operate any machines if you feel dizzy, drowsy or have
uncontrollable twitching, jerking or writhing movements and unusual muscle tone
leading to distortion of the body or your vision gets affected after taking
PERINORM MD 10MG TABLET. Consult your doctor for advice before taking PERINORM
MD 10MG TABLET.

Useful Diagnostic Tests

• Complete blood count