Paraxin 1000mg Injection 1ml

Introduction About PARAXIN 1000MG INJECTION

PARAXIN 1000MG INJECTION contains Chloramphenicol which belongs to the group of
medicine called Antibiotics. It is used to manage typhoid fever, bacterial
meningitis, rickettsial infections, intraocular infections. It is also used in
management when other antibiotics are not effective or unsuitable.

Typhoid fever is a bacterial infection that can spread throughout the body,
affecting many organs, without proper management, it can cause serious
complications and can be fatal.

Bacterial meningitis is a serious and life-threatening form of meningitis that
occurs due to a bacterial infection.

Rickettsial infections is a bacterial infection that are caused by an unusual
type of bacteria that can live only inside the cells of another org
of these infections are spread through ticks, mites, fleas or lice.

Before receiving this medicine, inform your doctor if you are allergic
(hypersensitive) to chloramphenicol. During the therapy your doctor might
recommend you for routine blood tests to monitor, as chloramphenicol can damage
blood cells.

Pregnant and breastfeeding women should consult their doctors before receiving
this medicine. Consult your doctor for advice.

The most common side effects are nausea, vomiting, diarrhoea, headache,
weakness, soreness at injection site. Consult your doctor if any of the above
side effects worsen or persist for a longer duration.

Uses Of PARAXIN 1000MG INJECTION

It is used to manage:

• typhoid fever
• bacterial meningitis
• rickettsial infections
• intraocular infections

How PARAXIN 1000MG INJECTION Works

Chloramphenicol is a semi-synthetic antibiotic. It diffuses through the
bacterial cell wall and binds to the ribosome of the bacteria, thereby managing
bacteria making an essential nutrient required for growth and multiplication. In
time, the number of bacteria is reduced and the infection is controlled.

How to use PARAXIN 1000MG INJECTION

PARAXIN 1000MG INJECTION will be administered intramuscularly (into a muscle) or
given intravenously (into a vein) by your doctor or nurse. Your doctor will
administer the correct dose for you depending upon your age, body weight and
disease condition.

Side Effects Of PARAXIN 1000MG INJECTION

Common

• soreness at the injection site
• fever
• skin rash, itching, swelling or hives
• headache
• nausea, vomiting
• diarrhoea
• white, furry, sore tongue and mouth
• sore and itchy vagina and white discharge
• eye pain, numbness, blurred vision or blind spots
• unusual tiredness, weakness, bleeding or bruising more easily than normal

Rare

Contact your doctor immediately, if you experience:

• blood and lymphatic system disorders such as blood dyscrasias including aplastic anaemia, hypoplastic anaemia, thrombocytopenia and granulocytopenia, pancytopenia and bone marrow depression
• glossitis and stomatitis and enterocolitis
• peripheral neuritis
• psychiatric disorders such as mild depression, mental confusion and delirium
• immune system disorders such as anaphylaxis, herxheimer reactions
• skin and subcutaneous tissue disorders such as angioedema, macular and vesicular rashes, urticaria
• new-born or premature infants, where the skin appears grey and the infant is listless and weak, symptoms such as vomiting, refusal to suck, fast irregular breathing, swelling of the stomach, blue discolouration or green coloured diarrhoea
• red raised areas on your skin which may look like spots or several inches across, which cause itchiness
• eye disorders such as o

How To Manage Side Effects

Nausea and Vomiting:

Receive this medicine with or just after a meal or a snack. Stick to simple
meals. Avoid eating rich or spicy food.

Diarrhoea:

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated.
Avoid taking any medicine on your own for managing diarrhoea. Consult your
doctor if the symptom did not improve.

Headache:

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a
pain-relieving balm on the head if required. Do not consume too much of alcohol.
Consult your doctor if the symptom did not improve.

Skin rash:

Avoid hot showers because hot water can irritate your skin further. Do not
scratch the affected area. Use protective clothing when going outdoors.
Regularly moisturize your skin. Consult your doctor if the symptom did not
improve.

Warning & Precautions

!### Pregnancy

PARAXIN 1000MG INJECTION is not recommended for use during pregnancy. Consult
your doctor before receiving this medicine.

!### Breastfeeding

PARAXIN 1000MG INJECTION is not recommended for use in breast feeding women.
Consult your doctor before receiving this medicine.

!### Driving and Using Machines

Do not drive or use any machines as this PARAXIN 1000MG INJECTION may cause
tiredness.

!### Kidney

PARAXIN 1000MG INJECTION should be used with caution in patients suffering from
kidney problems. Consult your doctor before receiving this medicine.

!### Liver

PARAXIN 1000MG INJECTION should be used with caution in patients suffering from
liver problems. Consult your doctor before receiving this medicine.

!### Allergy

Do not receive this medicine if you are allergic (hypersensitive) or
Chloramphenicol or any ingredients of this medicine.

Others

PARAXIN 1000MG INJECTION is not recommended for use if you:

• have any infections

Use in pediatrics:

PARAXIN 1000MG INJECTION should be used with caution in children. Your doctor
will administer the right dose depends on your child’s age, body weight and
disease condition. Consult your doctor before receiving this medicine.

Use in geriatrics:

PARAXIN 1000MG INJECTION should be used with caution in elderly patients.
Consult your doctor before receiving this medicine.

Interactions

A. Drug - Drug interactions:

Inform your physician if you are taking:

• alfent
• oral contrace
• phenobarbitone and rifampicin
• sulphonamides, metronidazole
• immunosuppressants such as tacrolimus
• medicines that may suppress the bone marrow such as carbamazepine, penicillamine
• warfarin (used to manage blood clot)
• phenytoin (manages epilepsy)
• other antibiotics such as azithromycin, erythromycin
• gliclazide, tolbutamide (used to manage diabetes)

Overdosage:

It is unlikely to receive an overdose since it will be administered by your
doctor or nurse, if you experience any unusual reactions, consult your doctor
immediately. Symptoms of overdosage includes nausea, vomiting and diarrhoea,
effects on blood cells and blood clotting.

Synopsis

Drug	:	Chloramphenicol
Pharmacological Category	:	Antibiotics
Therapeutic Indication	:	Typhoid fever, Bacterial meningitis, Rickettsial infections, Intraocular infections
Dosage Forms	:	Tablet, Capsule, Drops, Eye Drops, Eye Ointment, Injection, Syrup, Suspension, Caplet, Aplicap

More Information

• Keep out of reach of children
• Store in room temperature

FAQs About PARAXIN 1000MG INJECTION

How doesPARAXIN 1000MG INJECTIONgiven?

PARAXIN 1000MG INJECTION will be administered by a doctor or nurse. It is
usually injected intramuscularly (into a muscle) or given intravenously (into a
vein).

Is it safe to receivePARAXIN 1000MG INJECTIONfor longer duration of
time?

PARAXIN 1000MG INJECTION is received only through a doctor or nurse. Consult
your doctor if your condition does not improve despite receiving this medicine
for a week or if it worsens.

Can the use ofPARAXIN 1000MG INJECTIONcause diarrhoea?

Yes, the use of PARAXIN 1000MG INJECTIONmay cause diarrhoea along with the
desired effect, but not everyone gets them. It is an antibiotic that works
against bacteria. If you are experiencing severe diarrhoea, talk to the doctor
about it.

What if my condition does not improve after receivingPARAXIN 1000MG
INJECTION?

Talk to the doctor if your condition does not improve, even after receiving
PARAXIN 1000MG INJECTIONinjection. Consult your doctor for advice.

Useful Diagnostic Tests

• Complete Blood Count