Pacimol M 5/500mg Tablet 10'S

Introduction About PACIMOL M 5/500MG TABLET

PACIMOL M 5/500MG TABLET is a combination of Metoclopramide and Paracetamol
which belong to the groups of medicines called Antiemetics and Analgesics
respectively. It is used to manage pain, nausea and vomiting associated with
migraine attacks.

Migraine is a neurological condition that is thought to be caused by the
widening of certain blood vessels in the brain, causing an intense, throbbing,
recurrent headache on one side of the head, usually around the temple region,
but sometimes it can start in the forehead, around the eye or at the back of the
head. There are many symptoms that may accompany migraines; nausea (feeling
sick) is one of the most common.

Avoid consuming alcohol while taking PACIMOL M 5/500MG TABLET because it might
make you feel dizzy or sleepy. PACIMOL M 5/500MG TABLET is not recommended for
use in patients with stomach and/or digestive tract bleeding, intestinal
blockage, recent stomach and/or intestine surgery, phaeochromocytoma (a rare
tumour of the adrenal gland) or epilepsy.

PACIMOL M 5/500MG TABLET should only be used in pregnant women if necessary and
should be avoided in breastfeeding women. Before using PACIMOL M 5/500MG TABLET,
inform your doctor if you have any history of liver or kidney problems,
glutathione deficiency, hemolytic anaemia, dehydration, malnutrition for a long
period, breast cancer or Parkinson's disease.

PACIMOL M 5/500MG TABLET is generally not recommended for use in children under
the age of one year.PACIMOL M 5/500MG TABLET should also be used cautiously with
elderly patients. The most common side effects of PACIMOL M 5/500MG TABLET are
headache, dizziness, indigestion, drowsiness, tiredness, restlessness and
diarrhoea. If any of these symptoms worsen, consult your doctor.

Uses Of PACIMOL M 5/500MG TABLET

• Manage pain, nausea and vomiting associated with migraine attack

How PACIMOL M 5/500MG TABLET Works

PACIMOL M 5/500MG TABLET provides relief from migraine attacks where
Metoclopramide blocks the action of a chemical substance produced in the brain
that initiates vomiting along with increasing muscle contractions in the stomach
and intestine and Paracetamol works by stopping the release of certain chemical
messengers that cause pain and fever. This collective action is therefore useful
in managing nausea,  vomiting and headaches associated with migraine
effectively.

How to use PACIMOL M 5/500MG TABLET

Always use PACIMOL M 5/500MG TABLET as advised by your physician. Swallow the
medicine with a glass of water. Do not crush or chew the medicine. The correct
dose and duration of therapy will be decided by your doctor depending on your
age, weight and disease condition. Do not take more than the recommended dosage,
as it may lead to side effects.

Side Effects Of PACIMOL M 5/500MG TABLET

Common

• drowsiness
• depressed mood
• muscle spasms of your face and jaw, speech problems, unnatural tongue and rolling eyes, unnatural positioning of your head, shoulders and spine
• difficulty with movement, tremors or restlessness
• diarrhoea
• weakness

Uncommon

• increased milk production
• irregular or absent monthly periods
• hallucination
• decreased consciousness level

Rare

• feeling irritable and confused
• constipation
• feeling sick (nausea)
• dry mouth
• difficulty sleeping

Stop taking PACIMOL M 5/500MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• allergic reaction signs (skin rash, itching, swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing, wheezing or shortness of breath)
• signs of the neurole
• methaemoglobinaemia (bluish colouration of skin)
• signs of tardive dyskinesia (sudden mood changes, uncontrolled and repeated movements of the arms, legs, eyes, mouth, tongue, face and jaw)
• bruising more easily, sore throat or other signs of infection (these may be signs of a blood disorder)
• severe pain in the abdomen and back, with fever (high temperature), loss of appetite, nausea and vomiting (these may be signs of pancreas inflammation)

How To Manage Side Effects

Dizziness:

Sit down or lie down slowly when you are feeling dizzy. Take some time to rest
and drink plenty of water. Avoid coffee and other carbonated drinks. If the
symptom does not improve, contact your doctor.

Diarrhoea:

Drink lots of fluids, such as water or fruit juice, to keep yourself hydrated.
Do not consume any medicine on your own without consulting your doctor.

Warning & Precautions

!### Pregnancy

PACIMOL M 5/500MG TABLET is recommended for use in pregnant women or women
planning to become pregnant only if it is considered necessary. Therefore,
consult your doctor for advice.

!### Breastfeeding

PACIMOL M 5/500MG TABLET is not recommended for use in breastfeeding women as it
may pass into breast milk and can affect the breastfeeding infant. Consult your
doctor for advice.

Driving and Using Machines

Do not drive or operate any machines if you feel dizzy, drowsy or tired after
taking PACIMOL M 5/500MG TABLET.

!### Alcohol

Avoid consum
might make you feel dizzy or sleepy.

!### Kidney

PACIMOL M 5/500MG TABLET should be used with caution in patients with kidney
problems. Consult your doctor for advice.

!### Liver

PACIMOL M 5/500MG TABLET should be used with caution in patients having impaired
liver function and liver diseases such as Gilbert’s syndrome and glucose 6
phosphate dehydrogenase deficiency. Consult your doctor for advice.

!### Allergy

Do not take PACIMOL M 5/500MG TABLET if you are allergic to paracetamol or
metoclopramide.

!### Heart Disease

PACIMOL M 5/500MG TABLET should be used with caution in patients with a history
of abnormal heartbeats (QT interval prolongation) or any other heart problems.

Others

PACIMOL M 5/500MG TABLET is not recommended for use if you:

• have bleeding from the stomach and/or digestive tract
• have a blockage in the intestine
• have recent surgery on the stomach and/or intestine
• have phaeochromocytoma, a rare tumour of the adrenal gland
• have epilepsy

Before taking PACIMOL M 5/500MG TABLET inform your doctor if you:

• have glutathione deficiency
• have haemolytic anaemia
• have dehydration
• have malnutrition for a long period
• are weighed less than 50 kg
• have breast cancer
• have Parkinson's disease condition affecting muscle control

Use in Pediatrics:

PACIMOL M 5/500MG TABLET is not recommended for use in children less than 1 year
of age. Consult your doctor for advice.

Use in Geriatrics:

PACIMOL M 5/500MG TABLET should be used with caution in elderly patients.
Therefore, consult your doctor for advice.

Interactions

A. Drug-Drug interactions:

Before taking PACIMOL M 5/500MG TABLET, inform your doctor if you are taking any
of the following medicine:

• warfarin and clorindione (medicines used to manage blood clots)
• phenobarbital, phenytoin, carbamazepine, topiramate (medicines used to manage epilepsy)
• other medicines that relieve pain (Ex. codeine and morphine)
• medicines used to manage travel sickness, hayfever and allergy (dicyclomine, atropine and fesoterodine)
• medicines used to manage mental health illness (Ex. fluoxetine, risperidone, aripiprazole and clozapine)
• levodopa (a medicine used in the management of Parkinson's disease)
• digoxin (a medicine used to manage heart failure)

Overdosage:

If you or anyone else accidentally take too much of PACIMOL M 5/500MG TABLET,
consult your doctor immediately or visit the nearby hospital. Symptoms of an
overdose might include dizziness, drowsiness, confusion, increased sweating,
vomiting, stomach pain, convulsions or fits, uncontrolled muscle movements and
yellowing of the skin.

Synopsis

Drug	:	Metoclopramide, Paracetamol
Pharmacological Category	:	Dopamine antagonist, Analgesics
Therapeutic Indication	:	Nausea, vomiting and headache in migraine
Dosage Forms	:	Tablet, Suspension

More Information

• Keep PACIMOL M 5/500MG TABLET out of reach from children
• Store at room temperature

FAQs About PACIMOL M 5/500MG TABLET

Q: Can I stop taking PACIMOL M 5/500MG TABLET once I feel better?

A: No, do not stop taking PACIMOL M 5/500MG TABLET just because you feel better.
It is important that you complete the course of medicine prescribed for you by
the doctor. If you stop taking PACIMOL M 5/500MG TABLET too soon, your symptoms
may come back.

Q: Can PACIMOL M 5/500MG TABLET be used on children?

A: PACIMOL M 5/500MG TABLET is generally not recommended for use in children and
adolescents below 18 years of age. Therefore, consult your doctor before taking
PACIMOL M 5/500MG TABLET.

Q: Should I take PACIMOL M 5/500MG TABLET along with meals?

A: Yes, you can take PACIMOL M 5/500MG TABLET during meals or at any time
between meals. Always take this medicine exactly as your doctor has instructed.
If you have any doubts regarding it, please consult your doctor for advice.

Q: Can I consume alcohol while taking PACIMOL M 5/500MG TABLET?

A: No, you should not consume alcohol while taking PACIMOL M 5/500MG TABLET
because it might make you feel more dizzy or sleepy. This medicine should also
be used with caution in patients with alcohol dependence.

Useful Diagnostic Tests

• Complete blood count
• Liver function tests
• Fibrinogen level