MYCOTUF 250mg Tablet 10's

Introduction About MYCOTUF 250MG TABLET

MYCOTUF 250MG TABLET contains Ethionamide which belongs to the group of
medicines called Antitubercular drugs. It is used in the management of active
tuberculosis caused by a bacteria called M. tuberculosis resistant to other
antibiotics (Ex. isoniazid, rifampicin) or when the patient is intolerant to
other medicines. MYCOTUF 250MG TABLET is generally used in combination with
other medicines.

Tuberculosis is a serious bacterial infectious disease that affects the lungs.
The symptoms are unusual loss of weight, fever, cough, difficulty in breathing,
chest pain, loss of appetite, night sweats, etc.Your doctor may monitor your
blood sugar level, thyroid function and visual activity regularly while taking
MYCOTUF 250MG TABLET.

MYCOTUF 250MG TABLET is not recommended for use in patients having severe liver
disease. MYCOTUF 250MG TABLET is not recommended for use in pregnant women and
should be used with caution in breastfeeding women. MYCOTUF 250MG TABLET is not
recommended for use in children (below 12 years of age) except in some specific
disease conditions. Ask for your doctor’s advice before giving it to your child.

There is no information available on the use of MYCOTUF 250MG TABLET in elderly
patients, hence, consult your doctor before taking it. The most common side
effects of taking MYCOTUF 250MG TABLET are stomach discomfort, diarrhoea,
vomiting, nausea, headache, dizziness, general weakness, yellowing of the skin
and eyes, fever, fatigue, etc. If the symptoms do not improve, consult your
doctor.

Uses Of MYCOTUF 250MG TABLET

• Manage active tuberculosis resistant to other antibiotics (Ex. isoniazid, rifampicin) or when the patient is intolerant to other medicines

How MYCOTUF 250MG TABLET Works

MYCOTUF 250MG TABLET effectively reduces the tuberculosis infection by
inhibiting the pe
it kills or suppresses the growth of disease-causing bacteria.

How to use MYCOTUF 250MG TABLET

Always take MYCOTUF 250MG TABLET as directed by your physician. Swallow with a
glass of water and do not crush or chew it. Your doctor will prescribe the
correct dose and duration of MYCOTUF 250MG TABLET management depending upon your
age, body weight and health condition. Do not stop taking MYCOTUF 250MG TABLET
unless your doctor advises you to stop.

Side Effects Of MYCOTUF 250MG TABLET

Common

• stomach discomfort and pain
• diarrhoea, loss of appetite
• vomiting, nausea
• headache, drowsiness, dizziness
• general weakness
• pins and needle sensation (paraesthesia)
• signs of liver inflammation (hepatitis) including yellowing of the skin and eyes, fever, fatigue

Rare

• peripheral neuritis (nerve damage causing weakness, numbness of hand and feet)
• eye problems like o
• vitamin B3 deficiency or pellagra-like syndrome (dermatitis, diarrhea, dementia)

Stop taking MYCOTUF 250MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• liver injury (loss of appetite, nausea, yellow skin and whites of eye, discoloured stools, dark urine, pain and tenderness in the upper-right-side of the abdomen)
• signs of allergic reaction like fever and rash

How To Manage Side Effects

Nausea:

Take MYCOTUF 250MG TABLET with or just after meals. Stick to simple meals. Avoid
eating rich or spicy food, sugary snacks and drinks. Talk to your doctor if the
nausea doesn’t improve.

Drowsiness:

Take adequate sleep. Do not involve in rigorous activities. Do not interfere
with your sleep cycle. Talk to your doctor if the drowsiness doesn’t improve.

Vomiting:

Drink clear or ice-cold drinks, eat light, bland foods and avoid fried, oily or
sweet foods. Avoid drinking too much liquid along with your meals, drink slowly
in between meals. Consult your doctor if your symptom worsens.

Diarrhea:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do
not consume any medicine on your own without consulting your doctor. Consult
with your doctor if diarrhea doesn’t improve.

Stomach pain:

Try to rest and relax. Try to have smaller and frequent meals. Keep a heat pad
on your stomach. If the symptom does not improve, contact your doctor.

Dizziness

Lie or sit down immediately when you feel dizzy. If you're feeling severe
episode of spinning (vertigo), lie in a dark and quite place with eyes closed.
Try to avoid vehicle driving. Discuss with your doctor if the symptom worsens.

Headache:

Apply hot or cold-water bag on your head. Try to take rest in a quiet and dark
room. Drink tea or coffee. Massage on scalp or head with mild pressure. Consult
your doctor for advice.

Warning & Precautions

!### Pregnancy

There are no adequate and well controlled studies about the use of MYCOTUF 250MG
TABLET in pregnant women, hence, it is not recommended for use in women who are
pregnant or likely to become pregnant unless considered necessary by the doctor.
Consult your doctor about the risks and benefits before taking MYCOTUF 250MG
TABLET.

!### Breastfeeding

There is no information available on the use of MYCOTUF 250MG TABLET in
breastfeeding women, hence, it should be used only if the benefits outweigh the
risks to the baby. New-borns who are breast-fed by mothers taking MYCOTUF 250MG
TABLET should be monitored carefully. Consult your doctor before taking it.

!### Driving and Using Machines

Do not drive or use any machineries if you feel drowsy or have a headache after
taking MYCOTUF 250MG TABLET.

!### Alcohol

Avoid consum
psychotic reactions.

!### Liver

MYCOTUF 250MG TABLET is not recommended for use in patients having severe liver
disease. Consult your doctor for advice.

!### Allergy

Do not take MYCOTUF 250MG TABLET if you are allergic to Ethionamide or any of
the other ingredients of this medicine.

Others

Before taking MYCOTUF 250MG TABLET inform your doctor if you have:

• diabetes

Use in Pediatrics:

MYCOTUF 250MG TABLET is not recommended for use in children (below 12 years of
age) except in some specific disease conditions. Ask for your doctor’s advice
before giving it to your child.

Use in Geriatrics:

There is no information available on the use of MYCOTUF 250MG TABLET in elderly
patients. Consult your doctor before taking it.

Interactions

A. Drug - Drug interactions:

Before taking MYCOTUF 250MG TABLET, inform your doctor if you are taking any of
the following medicines:

• isoniazid and rifampicin (used to manage tuberculosis)

Overdosage:

If you or anyone else accidentally take too much of MYCOTUF 250MG TABLET,
consult your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Ethionamide
Pharmacological Category	:	Antitubercular drugs
Therapeutic Indication	:	Tuberculosis
Dosage Forms	:	Tablet

More Information

• Keep MYCOTUF 250MG TABLET out of reach of children
• Store MYCOTUF 250MG TABLET at a temperature below 30°C

FAQs About MYCOTUF 250MG TABLET

Can pregnant woman take MYCOTUF 250MG TABLET?

There are no adequate and well controlled studies about the use of MYCOTUF 250MG
TABLET in pregnant women, hence, it is not recommended for use in women who are
pregnant or likely to become pregnant unless considered necessary by the doctor.
Consult your doctor about the risks and benefits before taking MYCOTUF 250MG
TABLET.

Can MYCOTUF 250MG TABLET be given to children?

MYCOTUF 250MG TABLET is not recommended for use in children (below 12 years of
age) except in some specific disease conditions. Consult your child's doctor for
advice. The doctor will advise a proper dose or select a suitable alternative
management for your child.

Can MYCOTUF 250MG TABLET cause nerve related side effects?

MYCOTUF 250MG TABLET can cause peripheral neuritis (weakness, pain or numbness
in hands and feet) or o
doctor might prescribe you pyridoxine or vitamin B6 along with MYCOTUF 250MG
TABLET to reduce these side effects. Ask for your doctor’s advice.

For how long should I take MYCOTUF 250MG TABLET?

MYCOTUF 250MG TABLET should be taken exactly as directed by your doctor. Do not
stop taking it early or use it for a prolonged period. Skipping doses or not
completing the full term management of MYCOTUF 250MG TABLET may decrease the
effectiveness of the immediate management and increase the likelihood that
bacteria will develop resistance against MYCOTUF 250MG TABLET and will not be
manageable by this medicine or other antibacterial drugs in the future. Ask your
doctor if you wish to discontinue.

What are the tests that should be done frequently while taking MYCOTUF 250MG
TABLET?

While taking MYCOTUF 250MG TABLET, your doctor might ask you to check your blood
glucose levels priorly and periodically throughout therapy with MYCOTUF 250MG
TABLET. Patients having diabetes should be particularly alert for episodes of
hypoglycaemia. Periodic monitoring of thyroid function tests is recommended
while taking MYCOTUF 250MG TABLET as hypothyroidism may occur. Along with this,
your doctor may ask you to perform eye examinations.

Should MYCOTUF 250MG TABLET be taken with or without meals?

MYCOTUF 250MG TABLET can be taken with or without meals. It is preferable to
take it after meals, as this will help in reducing the gastrointestinal effects
of MYCOTUF 250MG TABLET. Ask for your doctor’s advice.

Useful Diagnostic Tests

• Mantoux test