Muply F Cream 10gm

Introduction About MUPLY F CREAM

MUPLY F CREAM is a combination of Fluticasone and Mupirocin which belongs to the
group of medicines called Corticosteroids and Antibiotics respectively. It is
used to manage steroid-responsive inflammatory disorders of the skin where
secondary bacterial infections are present, suspected, or likely to occur.

These include atopic dermatitis, nummular dermatitis (discoid eczemas), irritant
or allergic contact dermatitis, seborrhoeic dermatitis, prurigo nodularis,
psoriasis (excluding widespread plaque psoriasis), lichen simplex chronicus
(neurodermatitis) and lichen planus, discoid lupus erythematosus, insect bite
reactions, and miliaria (prickly heat).

Dermatitis is a common skin irritation which has many causes and forms and
usually involves itchy, dry skin or a rash, blistering, oozing, crust or flake
off. Psoriasis is a long-term skin disease that causes a rash with itchy, scaly
patches, most commonly on the knees, elbows, trunk, and scalp which can be
painful, interfere with sleep and make it hard for you to focus.

During course of the management your doctor might regularly examine your skin to
avoid any untoward side effects.

MUPLY F CREAM is not recommended for long-term continuous use in infants,
children and adolescents under 12 years of age.

Before using MUPLY F CREAM inform your doctor if you have skin conditions such
as rosacea, acne vulgaris, perioral dermatitis, pruritus without inflammation,
perianal and genital pruritus, primary or secondary viral, yeast, fungal and
bacterial infections, or dermatoses in infants under 3 months of age.

MUPLY F CREAM should be used in pregnant and breastfeeding women only if
specifically directed by your doctor.

The most common side effects of using MUPLY F CREAM are burning, or itching.
Contact your doctor if any of the side effects worsen.

Uses Of MUPLY F CREAM

It is used to manage:

• atopic, nummular, irritant or allergic contact, and seborrhoeic dermatitis
• prurigo nodularis
• psoriasis
• lichen simplex chronicus and lichen planus
• discoid lupus erythematosus
• insect bite reactions
• miliaria

How MUPLY F CREAM Works

MUPLY F CREAM relieves skin infection and inflammation where fluticasone
exerts a direct local effect of blood vessel constriction and anti-inflammatory
action by decreasing inflammatory cells like eosinophils, monocytes, mast cells,
macrophages, and dendritic cells, along with the number of cytokines they
produce, and decreasing mucus gland secretions. Mupirocin mediates its
antibacterial activity by blocking the bacterial protein synthesis and formation
of bacterial proteins essential for survival.

How to use MUPLY F CREAM

Apply MUPLY F CREAM as advised by your physician. It is for external use only.
Your doctor will decide the correct dose and duration for you depending upon
your age, body weight and disease condition.

Side Effects Of MUPLY F CREAM

Common

• burning, itching

Uncommon

• redness
• stinging and dryness (area of application)
• cutaneous sensitization reactions

Rare

Stop using MUPLY F CREAM and consult your doctor immediately if you experience
any of the following side effects:

• symptoms of Cushing’s syndrome and reversible hypothalamic-pituitary adrenal (HPA) axis suppression
• blurred vision or other visual disturbances

Warning & Precautions

!### Pregnancy

MUPLY F CREAM should be used in pregnant women only if specifically directed by
your doctor. Consult your doctor before using the medicine.

!### Breastfeeding

MUPLY F CREAM should be used in breastfeeding women only if specifically
directed by your doctor. It should not be applied to the breasts to avoid
accidental ingestion by the baby. Consult your doctor before using the medicine.

!### Kidney

MUPLY F CREAM should be used in minimum quantity for the shortest duration in
patients with kidney impairment. Consult your doctor before using it.

!### Liver

MUPLY F CREAM should be used in minimum quantity for the shortest duration in
patients with liver impairment. Consult your doctor before using it.

!### Allergy

Do not use MUPLY F CREAM if you are allergic to Fluticasone, Mupirocin or any
other ingredients of this medicine.

Others

MUPLY F CREAM is not recommended for use if you have:

• rosacea
• acne vulgaris
• perioral dermatitis
• pruritus without inflammation
• perianal and genital pruritus
• primary or secondary viral, yeast, fungal and bacterial infections

Use in pediatrics:

MUPLY F CREAM should be used with caution in children and infants aged 3 months
and over. Your doctor will prescribe the right dose depends on your child’s age,
body weight and severity of infection. Consult your doctor before using it.

Use in geriatrics:

MUPLY F CREAM should be used in minimum quantity for the shortest duration in
elderly patients. Consult your doctor before using it.

Interactions

A. Drug - Drug interactions:

Before using MUPLY F CREAM inform your doctor if you are taking any of the
following medicines:

• ritonavir (used to manage HIV infection)
• itraconazole (used to manage fungal infection)

Overdosage:

If you or anyone else accidentally uses too much of MUPLY F CREAM, contact your
doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Fluticasone, Mupirocin
Pharmacological Category	:	Corticosteroids, Antibiotic
Therapeutic Indication	:	Skin infection and inflammation
Dosage Forms	:	Cream, Ointment

More Information

• Keep MUPLY F CREAM out of reach of children
• Do not store above 25°C

FAQs About MUPLY F CREAM

Can I stop using MUPLY F CREAM?

Do not stop using MUPLY F CREAM unless your doctor advises you to stop.
Management with topical corticosteroids should be gradually withdrawn once
control is achieved as rebound of pre-existing skin disease can occur with
abrupt discontinuation.

Can I use MUPLY F CREAM for acne?

Do not use MUPLY F CREAM for conditions other than that prescribed for, and it
is not recommended for use in acne vulgaris. Consult your doctor before using
it.

Can I apply MUPLY F CREAM on the face?

Long-term application of MUPLY F CREAM on the face is not recommended, as this
area is more susce
it.

Can MUPLY F CREAM be used for psoriasis?

MUPLY F CREAM should be used with caution in psoriasis as rebound, tolerance,
risk of generalized pustular psoriasis and local or systemic toxicity due to
impaired barrier function of the skin can occur. Careful patient supervision is
important when used in psoriasis. Consult your doctor before using it.

What if MUPLY F CREAM accidentally gets into my eye?

Avoid contact of MUPLY F CREAM with the eyes to ensure it does not enter the eye
as cataract and glaucoma might result from repeated exposure. If contaminated,
wash your eyes thoroughly with water until the medicine residues have been
removed. Consult your doctor if you feel any eye discomfort.