MS 120mg Capsule 14'S

Introduction About MS 120MG CAPSULE

MS 120MG CAPSULE contains Dimethyl Fumarate which belongs to the group of
medicines called Immunosuppressive Agent. It is used to manage
relapsing-remitting forms of multiple sclerosis in patients aged 13 years and
older. Multiple sclerosis is a long-term condition that affects the brain and
the spinal cord. Relapsing-remitting Multiple sclerosis is characterised by
repeated attacks (relapses) of nervous system symptoms such as walking
difficulties, feeling off balance, visual difficulties (e.g., blurred, or double
vision).

Before and during the management your doctor will perform blood tests to
determine your health condition. Avoid consum
120MG CAPSULE as it may cause gastritis (inflammation of the stomach). MS 120MG
CAPSULE is not recommended in patients with (PML) progressive multifocal
leukoencephalopathy (a rare brain infection). MS 120MG CAPSULE should be used
with caution in patients with lung problems (such as pneumonia), severe kidney
and liver problems, stomach or bowel disease.

MS 120MG CAPSULE is generally not recommended for use in pregnant
or breastfeeding women. Safety data of MS 120MG CAPSULE for children below 13
years of age has not been established yet. The most common side effects of
taking MS 120MG CAPSULE are flushing (reddening of face), diarrhea, nausea or
stomach pain. Contact your doctor if your symptoms get worse.

Uses Of MS 120MG CAPSULE

• manages relapsing-remitting forms of multiple sclerosis

How MS 120MG CAPSULE Works

MS 120MG CAPSULE functions by managing the body's defence mech
destroying the brain and spinal cord. Additionally, it might manage multiple
sclerosis from getting worse in the future.

How to use MS 120MG CAPSULE

Take MS 120MG CAPSULE as advised by your physician. Take the medicine with a
glass of water. Do not crush, dissolve or chew the medicine. Take it with food.
Depending on your age, body weight, and medical state, your doctor will
determine the appropriate dose and duration for you.

Side Effects Of MS 120MG CAPSULE

Common

• reddening of the face or body feeling warm, hot, burning or itchy (flushing)
• loose stools (diarrhoea)
• nausea and vomiting
• stomach pain or stomach cramps
• gastroenteritis (inflammation of the lining of intestines), gastritis (stomach lining inflammation)
• dyspepsia (unable to digest)
• itchy skin, rashes
• erythema (red or pink blotches on the skin)
• hair loss
• throat pain, cough, and painful menstrual periods (mostly in children)

Rare

• allergic reactions

Stop taking MS 120MG CAPSULE and contact your physician immediately if you
experience any of the following side effects:

• severe (anaphylaxis) allergic reactions such as reddening of the face or body,feeling warm, hot, burning, or itchy (flushing), red rash or hives (rashes), angioedema (swelling of the face, lips, mouth, or tongue), wheezing, shortness of breath or difficulty breathing, hypotension (loss of consciousness or dizziness)
• serious kidney disorder (Fanconi Syndrome) (symptoms include passing more urine, drinking more water than normal, weaker muscles, you break a bone, or just have aches and pains)
• symptoms of herpes zoster (shingles)
• a rare brain infection called progressive multifocal leukoencephalopathy (PML) (symptoms include new or worsening weakness on one side of the body, clumsiness, changes in vision, thinking, memory, personality changes, or communication difficulties)

How To Manage Side Effects

Diarrhoea:

Drink plenty of water and fruit juice to keep yourself hydrated. Contact your
doctor if the diarrhoea did not improve.

Nausea and vomiting:

Stick to simple meals. Avoid eating oily or spicy food. If nausea and vomiting
does not improve, consult your doctor.

Skin rash:

Hot water can irritate the skin, so avoid taking hot showers. Do not scratch the
affected area. Contact your doctor if the rashes did not improve.

Stomach pain:

Avoid oily and spicy food. Keep a heat pad on your stomach. consult your doctor
if symptoms do not improve.

Warning & Precautions

!### Pregnancy

MS 120MG CAPSULE is generally not recommended for use in pregnant women or women
planning to have a baby, unless considered necessary. Contact your doctor before
taking MS 120MG CAPSULE.

!### Breastfeeding

MS 120MG CAPSULE is generally not recommended for use in breastfeeding women,
unless considered necessary. Contact your doctor before taking MS 120MG CAPSULE.

!### Driving and Using Machines

MS 120MG CAPSULE does not affect your ability to drive or operate machines.

!### Alcohol

Avoid consum
gastritis (inflammation of the stomach), especially in those who are already at
risk for gastritis. Contact your doctor before taking MS 120MG CAPSULE.

!### Kidney

MS 120MG CAPSULE should be used with caution in patients with severe kidney
disease. Contact your doctor before taking MS 120MG CAPSULE.

!### Liver

MS 120MG CAPSULE should be used with caution in patients with severe liver
diseases. Contact your doctor before taking MS 120MG CAPSULE.

!### Allergy

Do not take MS 120MG CAPSULE if you are allergic (hypersensitive) to dimethyl
fumarate or any other ingredients of this medicine.

!### Lungs

MS 120MG CAPSULE should be used with caution in patients with lung diseases
(such as pneumonia). Contact your doctor before taking MS 120MG CAPSULE.

Others

MS 120MG CAPSULE is not recommended for use if you:

• have (PML) progressive multifocal leukoencephalopathy (a rare brain infection)

Before taking MS 120MG CAPSULE, inform your doctor if you have:

• stomach or bowel disease

Use in paediatrics:

Safety data of MS 120MG CAPSULE for children below 13 years of age has not been
established yet. Contact your doctor before taking MS 120MG CAPSULE.

Interactions

A. Drug-Drug interactions:

Before taking MS 120MG CAPSULE, inform your doctor if you are taking any of the
following medicine:

• fumarates (fumaric acid esters) (used to manage psoriasis)
• other medications that affect the immune system (Ex. natalizumab, fingolimod, alemtuzumab, teriflunomide, ocrelizumab or cladribine)
• medicines to manage cancer (Ex. rituximab or mitoxantrone)
• medications that can have harmful effects on the kidneys, which include some antibiotics (Ex. gentamicin, neomycin)
• diuretics (used to manage blood pressure)
• specific types of painkillers (such as ibuprofen)
• lithium (used for mental illness)
• live vaccines (medicines used to manage infections)

Overdosage:

If you or anyone else accidentally takes too much of MS 120MG CAPSULE, consult
your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Dimethyl Fumarate
Pharmacological Category	:	Immunosuppressive Agent
Therapeutic Indication	:	Relapsing forms of multiple sclerosis
Dosage Forms	:	Capsule

More Information

• Keep MS 120MG CAPSULE out of the sight and reach of children
• Store MS 120MG CAPSULE below 25°C

FAQs About MS 120MG CAPSULE

What is MS 120MG CAPSULE used for?

MS 120MG CAPSULE is used to manage relapsing-remitting forms of multiple
sclerosis in patients aged 13 years and older. Relapsing-remitting Multiple
sclerosis is characterised by repeated attacks (relapses) of nervous system
symptoms such as walking difficulties, feeling off balance, visual difficulties
(e.g., blurred, or double vision).

What are the parameters to be monitored while taking MS 120MG CAPSULE?

Prior to the management your doctor will perform blood tests to determine the
number of white blood cells and frequent monitoring of the liver and kidney is
recommended during therapy. Consult your doctor for more information.

How does MS 120MG CAPSULE work?

MS 120MG CAPSULE functions by managing the body's defence mech
destroying the brain and spinal cord. Additionally, it might manage Multiple
Sclerosis from getting worse in the future.

Can MS 120MG CAPSULE be used in pregnant and breastfeeding women?

No, MS 120MG CAPSULE is generally not recommended for use in pregnant and
breastfeeding women, unless considered necessary. Contact your doctor before
taking MS 120MG CAPSULE.

Can MS 120MG CAPSULE affect thyroid function?

No, MS 120MG CAPSULE does not affect the functioning of the thyroid gland (an
organ that secretes hormones to regulate metabolism). Consult your doctor for
more information.

Useful Diagnostic Tests

• complete blood count
• kidney function test
• liver function test
• magnetic resonance imaging scan