MARKTORVA 40 Tablet 10's

Introduction About MARKTORVA 40 TABLET

MARKTORVA 40 TABLET is used to reduce elevated high blood cholesterol levels
(hyperlipidaemia) in patients when diet and lifestyle changes does not result in
adequate response. It contains Atorvastatin which belongs to the group of
medicines called Lipid-lowering drugs. By reducing blood cholesterol levels,
MARKTORVA 40 TABLET can also manage the risk of heart attack, stroke, angina or
related health problems. MARKTORVA 40 TABLET can be used both in adults and in
children (aged 10 years or above). It effectively reduces the levels of bad
cholesterol (LDL) and triglycerides in the body by blocking the action of an
enzyme called HMG-CoA reductase that synthesizes cholesterol within the body.

Along with the management, follow a cholesterol-lowering diet, lifestyle changes
and regular physical activity as instructed by your doctor to achieve better
results. Avoid consuming alcohol or grapefruit juice while taking MARKTORVA 40
TABLET as it may make MARKTORVA 40 TABLET less effective. Before taking
MARKTORVA 40 TABLET inform your doctor if you have any lung, liver, kidney, or
heart problems. You must also inform your doctor if you have diabetes, thyroid
problems, or a family history of muscle disorders. Talk to your doctor before
taking MARKTORVA 40 TABLET if you are already taking any antibiotics (fusidic
acid) to manage any existing infections. Do not take MARKTORVA 40 TABLET if you
are pregnant or breastfeeding without consulting your doctor.

MARKTORVA 40 TABLET may increase blood sugar levels, especially in patients who
are diabetic. It may also affect the way your liver works, and so your doctor
will closely monitor your blood sugar levels and liver functions while
undergoing therapy with MARKTORVA 40 TABLET as a precaution. The most common
side effects of taking MARKTORVA 40 TABLET are inflammation of nasal passage,
throat pain, muscle ache, joint pain, back pain, constipation, nausea and
headache. Consult your doctor if any of these side effect worsens. Also, inform
your doctor if you experience severe unexplained muscle pain, tenderness or
weakness along with fever after taking MARKTORVA 40 TABLET.

Uses Of MARKTORVA 40 TABLET

It is used to manage:

• high blood cholesterol levels
• the risk of heart attack, stroke, angina or related health problems

How MARKTORVA 40 TABLET Works

MARKTORVA 40 TABLET is a lipid lowering medicine. It effectively reduces the
levels of bad cholesterol (LDL) and triglycerides in the body by blocking the
action of an enzyme called HMG-CoA reductase that synthesizes cholesterol within
the body. It also acts on the liver and improve the body’s ability to remove
lipid particles from the blood. As a result, it reduces blood cholesterol levels
and manage its associated risks.

How to use MARKTORVA 40 TABLET

Take MARKTORVA 40 TABLET as advised by your physician. Swallow the medicine with
a glass of water. Do not crush or chew the medicine. Your doctor will decide the
correct dose and duration of therapy for you depending upon your age, body
weight and health condition. Do not stop taking MARKTORVA 40 TABLET without
consulting your doctor.

Side Effects Of MARKTORVA 40 TABLET

Common side effects of MARKTORVA 40 TABLET:

• inflammation of the nasal passages
• throat pain
• nose bleeds
• allergic reaction
• increase in blood sugar levels or creatine kinase
• headache
• nausea, vomiting
• constipation
• indigestion
• diarrhoea
• joint pain, muscle pain, back pain, neck pain
• liver problems
• anorexia
• weight gain
• dizziness
• nightmares, insomnia
• tingling sensation
• changes in sense of taste
• blurring of vision
• ringing in the ears followed by vomiting
• bloating, abdominal pain
• muscle fatigue, weakness
• swelling especially in the ankles (oedema)
• raised temperature

Stop taking MARKTORVA 40 TABLET and contact your doctor immediately if you
experience any of the following side effects:

• unexplained muscle pain or weakness, especially if accomp
• unexpected bleeding or bruising

Warning & Precautions

!### Pregnancy

ContraindicatedMARKTORVA 40 TABLET is not recommended for use in pregnant women. Women of
childbearing age must use a reliable contrace
while undergoing therapy with MARKTORVA 40 TABLET.

!### Breastfeeding

ContraindicatedMARKTORVA 40 TABLET is not recommended for use in breastfeeding women.

!### Driving and Using Machines

Use with CautionDo not drive or operate any heavy tools or machines if you feel dizzy or sleepy
after taking MARKTORVA 40 TABLET.

!### Alcohol

Consult your doctorMARKTORVA 40 TABLET should be used with caution in patients who consume large
amounts of alcohol. Therefore, it is advisable to avoid alcohol consum
while taking MARKTORVA 40 TABLET to achieve maximum benefits.

!### Kidney

Use with CautionMARKTORVA 40 TABLET should be used with caution in patients with kidney
problems.

Liver

Consult your doctorMARKTORVA 40 TABLET is not recommended for use in patients with severe liver
diseases. It should be used with caution in patients with a history of liver
problems.

!### Allergy

ContraindicatedDo not take MARKTORVA 40 TABLET if you are allergic to Atorvastatin or any other
ingredients of this medicine.

!### Lungs

Use with CautionMARKTORVA 40 TABLET should be used with caution in patients with lung diseases
(such as severe respiratory failure).

!### Heart Disease

Use with CautionMARKTORVA 40 TABLET should be used with caution in patients with high blood
pressure.

!### Use In Pediatrics

Monitoring requiredMARKTORVA 40 TABLET should be used in children and adolescents (aged 10 years or
older) only if prescribed by the physician. Your doctor will decide the correct
dose of MARKTORVA 40 TABLET depending on your child’s age, body weight and
health condition.

!### Use In Geriatrics

Use with CautionMARKTORVA 40 TABLET should be used with caution in elderly patients (aged 70
years or older).

Others

Before taking MARKTORVA 40 TABLET, inform your doctor if you:

• have an unexplained muscle pain
• had any muscle problems in the past
• have improper functioning of thyroid gland
• have personal or family history of muscle problems
• are alcoholic
• have diabetes
• are overweight
• have a previous history of stroke with bleeding the brain
• have small holes or pockets in the brain due to previous stroke

Interactions

A. Drug-Drug interactions:

Before taking MARKTORVA 40 TABLET, inform your doctor if you are taking any of
the following medicines such as:

• Immunosuppressants (Ex. cyclosporine)
• Antibiotics (Ex. fusidic acid, erythromycin, clarithromycin, telithromycin)
• Antifungals (Ex. ketoconazole, itraconazole, voriconazole, fluconazole, posaconazole)
• Anti-TB agents (Ex. rifampicin)
• Anti-lipidemic agents (Ex. gemfibrozil, fenofibrate, colestipol or ezetimibe)
• Cardiac medicines (Ex. amlodipine, diltiazem, digoxin, verapamil, amiodarone)
• Anti-viral agents (Ex. letermovir, ritonavir, lopinavir, atazanavir, indinavir, darunavir, the combination of tipranavir/ritonavir, telaprevir, boceprevir and the combination of elbasvir/grazoprevir, ledipasvir/sofosbuvir)
• Anti-coagulants (Ex. warfarin)
• Oral contrace
• Anticonvulsants (Ex. stiripentol)
• H2 blockers (Ex. cimetidine)
• Antacids (Ex. aluminium hydroxide or magnesium hydroxide)
• Nonsteroidal anti-inflammatory drug (Ex. phenazone)
• Anti-gout agents (Ex. colchicine)
• Herbal medicine (Ex. St John’s wort )

B. Drug-Food interactions:

Avoid consum
reduce its effectiveness.

Overdosage:

If you or anyone else accidentally took more MARKTORVA 40 TABLET, consult your
doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Atorvastatin
Pharmacological Category	:	HMG-CoA reductase inhibitors
Therapeutic Indication	:	Hyperlipidaemia
Dosage Forms	:	Tablet

More Information

FAQs About MARKTORVA 40 TABLET

Q: What is MARKTORVA 40 TABLET used for?

A: MARKTORVA 40 TABLET is a lipid lowering medicine. It is used to control
elevated blood cholesterol levels. By reducing blood cholesterol levels,
MARKTORVA 40 TABLET can also manage the risk of heart attack, stroke, angina or
related health problems.

Q: Can the use of MARKTORVA 40 TABLET cause diabetes?

A: Yes. MARKTORVA 40 TABLET may increase blood sugar levels in some patients.
This is most predominantly seen in patients who already have diabetes along with
obesity and/or hypertension. Therefore, consult your doctor before taking this
medicine if you are diabetic, obese or have hypertension. Your doctor will
closely monitor your blood sugar levels while undergoing therapy with MARKTORVA
40 TABLET to avoid any unwanted side effects.

Q: What is the best time to take MARKTORVA 40 TABLET?

A: Take MARKTORVA 40 TABLET as advised by your physician. Your doctor will
decide the best time for you to take MARKTORVA 40 TABLET. Try to take this
medicine at the same time each day. It can be taken with or without food.

Q: What are the side effects of taking MARKTORVA 40 TABLET?

A: The most common side effects of taking MARKTORVA 40 TABLET are pain in joints
and muscles, gastrointestinal problems such as constipation, diarrhoea,
indigestion or nausea and headache. Contact your doctor if any of side effect
worsens. Also, inform your doctor if you experience severe unexplained muscle
pain, tenderness, or weakness along with fever after taking this medicine.

Q: Can I consume alcohol along with MARKTORVA 40 TABLET?

A: MARKTORVA 40 TABLET should be used with caution in patients who consume large
amounts of alcohol. Therefore, it is advisable to avoid alcohol consum
while taking this medicine to achieve maximum benefits.

Q: Can the use of MARKTORVA 40 TABLET make me feel more tired?

A: Yes. The use of MARKTORVA 40 TABLET can make you feel more tired, because it
acts by reducing the supply of energy to the muscles present in your body.
However, you may also feel tired due to other reasons such as severe liver
damage. Consult your doctor if you experience excessive tiredness with muscle
pain.

Q: Who should not take MARKTORVA 40 TABLET?

A: MARKTORVA 40 TABLET is not recommended for use in patients with severe liver
damage. It is also not suitable for use in patients having muscle problems. If
you are pregnant or breastfeeding consult your doctor before taking MARKTORVA 40
TABLET. Before taking MARKTORVA 40 TABLET inform your doctor if you have
diabetes or any kidney or heart problems. Do not take this medicine if you are
undergoing therapy with antibiotics such as fusidic acid.

Q: What are the dietary restrictions that I need to follow while taking MARKTORVA 40 TABLET?

A: While taking MARKTORVA 40 TABLET, follow a low-cholesterol diet as instructed
by your doctor and avoid excessive alcohol intake. Avoid eating oil rich or
deep-fried foods. Limit your sugar intake by avoid eating biscuits, cakes, soft
drinks, or pastries. Stick to a simple nutritious diet. Avoid consum
grapefruit while taking MARKTORVA 40 TABLET as it may reduce its effectiveness.

Q: Can I stop taking MARKTORVA 40 TABLET once my blood cholesterol level is controlled?

A: Do not stop taking this medicine without consulting your doctor, as it could
once again increase your blood cholesterol levels. MARKTORVA 40 TABLET can only
control your blood cholesterol levels and cannot cure them completely,
therefore, it is important to take this medicine until your doctor advises you
to stop.

Q: Can I take MARKTORVA 40 TABLET if I am diabetic?

A: MARKTORVA 40 TABLET may increase blood sugar levels in some patients. This is
most predominantly seen in patients who already have diabetes along with obesity
and/or hypertension. Therefore, consult your doctor before taking MARKTORVA 40
TABLET if you are diabetic, obese or have hypertension.

Q: Does MARKTORVA 40 TABLET cause muscle pain?

A: MARKTORVA 40 TABLET may cause a rare but serious side effect of unexplained
muscle pain or weakness called rhabdomyolysis. It might be an early sign of a
potentially serious muscle degradation. Therefore, consult your doctor if you
experience any signs of muscle problems after taking MARKTORVA 40 TABLET. Also,
talk to your doctor before taking MARKTORVA 40 TABLET if you already have weak
muscles or have a family history of any muscle disorders.

Q: How long should I take MARKTORVA 40 TABLET to manage high cholesterol?

A: You should take MARKTORVA 40 TABLET as long as your doctor advises you to
take. Because MARKTORVA 40 TABLET will only help you in managing your
cholesterol levels and cannot completely cure them. If you stop using MARKTORVA
40 TABLET, your cholesterol levels may raise once again.

Q: Can MARKTORVA 40 TABLET be taken by pregnant or breast-feeding women?

A: MARKTORVA 40 TABLET is not recommended for use in pregnant or breast-feeding
women. Therefore, consult your doctor before taking it. Women of childbearing
age must use a reliable contrace
therapy with this medicine. However, if you accidentally become pregnant while
taking this medicine, stop taking it and consult your doctor immediately.

Useful Diagnostic Tests

• Bilirubin (Total + Direct)
• Lipid Profile
• Liver Function Test (LFT)
• Lipid Profile-Extended
• HDL Cholesterol – Direct
• LDL Cholesterol - Direct
• Triglycerides (TGL)
• Cholesterol Total -Serum