MANOHEXY 5MG TABLET 10'S

Introduction About MANOHEXY 5MG TABLET

MANOHEXY 5MG TABLET contains Trihexyphenidyl which belongs to the group of
medicines called Central Anticholinergics. It is used to improve muscle control
in patients with Parkinson’s disease. Parkinson’s disease is a long-term brain
disorder that causes muscle stiffness, shaking, slow and unsteady movements,
difficulty in walking and loss of balance. It happens due to loss of nerve cells
at certain regions of brain (basal ganglia) that controls body movements.

MANOHEXY 5MG TABLET can also be used to control abnormal involuntary muscle
movements (such as extreme restlessness or muscle spasms) in the body that is
caused due to the use of certain medicines.

Trihexyphenidylis a muscle relaxant. It reduces muscle stiffness and relaxes
muscles by reducing the activity of a chemical messenger called acetylcholine in
the brain. It also restores a balance between certain brain chemicals (dopamine
and acetylcholine) that controls body movements.

Before taking MANOHEXY 5MG TABLET, inform your doctor if you have glaucoma, high
blood pressure, stomach ulcer or problems in your prostate gland. You must also
inform your doctor if you have any liver, kidney, or heart problems before
taking MANOHEXY 5MG TABLET as a precaution.

Talk to your doctor before taking MANOHEXY 5MG TABLET if you have myasthenia
gravis (muscle weakness) or tardive dyskinesia (unusual movements of face and
tongue). Consult your doctor before taking MANOHEXY 5MG TABLET if you are
pregnant or breastfeeding.

The most common side effects of taking MANOHEXY 5MG TABLET are dry mouth,
constipation, dizziness, blurred vision, nausea, and vomiting. Consult your
doctor if any of these side effect worsens.

Uses Of MANOHEXY 5MG TABLET

It is used to:

• Reduce muscle stiffness and improve muscle control in patients with Parkinson’s disease
• Manage drug-induced abnormal involuntary muscle movements (such as extreme restlessness or muscle spasms)

How MANOHEXY 5MG TABLET Works

MANOHEXY 5MG TABLET is an anticholinergic medicine with muscle relaxing
properties. It reduces muscle stiffness and improves muscle control by reducing
the activity of a chemical messenger called acetylcholine in the brain. It also
regulates the release of a brain chemical called dopamine that regulates proper
body movements and coordination. As a result, it reduces abnormal muscle
movements associated with Parkinson’s disease and with the use of certain
medicines.

How to use MANOHEXY 5MG TABLET

Take MANOHEXY 5MG TABLET as advised by your physician. Swallow MANOHEXY 5MG
TABLET with a glass of water. Do not chew or crush the medicine. It must be
taken with or just before meals.

Your doctor will decide the correct dose and duration of therapy for you
depending upon your age, body weight and disease condition. Continue to take
MANOHEXY 5MG TABLET for the stipulated duration as advised by your doctor
without any interru

Side Effects Of MANOHEXY 5MG TABLET

Common

• dry mouth
• constipation
• dizziness
• blurred vision
• nausea
• nervousness

Uncommon

Stop taking MANOHEXY 5MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• feeling restless, agitated, or confused
• delusion (false beliefs), hallucinations (seeing or hearing things that does not exist)
• difficulty in sleeping
• immediate or short-term memory loss
• worsening of myasthenia gravis (muscle pain or weakness)
• eye problems (dilated pupils, eye discomfort and increased sensitivity to light, eye pain)
• fast heartbeat
• fever, skin rash with redness or dryness
• inability to pass urine, feeling thirsty

How To Manage Side Effects

!### Constipation

Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals.
Drink plenty of fluids. Exercise more regularly. Consult your doctor if this
side effect bothers you.

!### Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or
machines completely while you are feeling dizzy. Do not consume excessive
alcohol, as it could aggravate your dizziness. Consult your doctor if your
dizziness worsens.

!### Dry Mouth

Drink plenty of water or fluids at regular intervals. Frequent small sips of
water or the use of artificial saliva may be beneficial. However, if it bothers
you or if your condition worsens contact your doctor.

!### Nausea And Vomiting

Take MANOHEXY 5MG TABLET with or just after meals. Stick to simple meals. Avoid
eating oil rich or spicy foods. Consult your doctor if your nausea worsens.

Warning & Precautions

!### Pregnancy

ContraindicatedMANOHEXY 5MG TABLET is not recommended for use in pregnant women. Therefore,
consult your doctor before taking it.

!### Breastfeeding

ContraindicatedMANOHEXY 5MG TABLET is not recommended for use in breastfeeding women.
Therefore, consult your doctor before taking it.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if you feel dizzy after taking MANOHEXY 5MG
TABLET.

!### Alcohol

Consult your doctorAvoid consum

!### Kidney

Use with CautionMANOHEXY 5MG TABLET should be used with caution in patients with kidney
problems. Therefore, consult your doctor before taking it.

!### Liver

Use with CautionMANOHEXY 5MG TABLET should be used with caution in patients with liver problems.
Therefore, consult your doctor before taking it.

!### Allergy

ContraindicatedDo not take MANOHEXY 5MG TABLET if you are allergic to Trihexyphenidyl.

!### Heart Disease

Use with CautionMANOHEXY 5MG TABLET should be used with caution in patients with heart problems
(such as high blood pressure). Therefore, consult your doctor before taking it.

!### Use In Pediatrics

Use with CautionMANOHEXY 5MG TABLET should be used with caution in children and adolescents
(below 18 years). Therefore, consult your doctor before taking it.

!### Use In Geriatrics

Use with CautionMANOHEXY 5MG TABLET should be used with caution in elderly patients (aged 65
years or above). Therefore, consult your doctor before taking it.

Others

Before taking MANOHEXY 5MG TABLET, inform your doctor if you:

• have glaucoma (increased pressure in the eye)
• have problems in prostate gland
• have difficulty in passing urine
• have stomach ulcer, severe heartburn, acid indigestion or any other digestive disorders
• suffer from myasthenia gravis (muscle weakness)
• have tardive dyskinesia (unusual movements of the face and the tongue)

Interactions

A. Drug-Drug Interactions:

Before taking MANOHEXY 5MG TABLET, inform your doctor, if you are taking any of
the following medicines such as:

• aspirin (a medicine used to relieve pain and reduce fever)
• medicine used for depression such as monoamine oxidase inhibitors (Ex. moclobemide, tranylcypromine) or tricyclic antidepressants (Ex. amitriptyline)
• medicines used to manage mental illness (Ex. chlorpromazine, thioridazine, clozapine)
• antihistamines (medicines used to manage allergies) Ex. cetirizine, desloratadine, fexofenadine
• disopyramide (a medicine used to manage irregular heartbeat)
• levodopa (a medicine used to manage parkinson’s disease)
• amantadine (a medicine used for viral infections)
• nefopam (a medicine used for pain relief)
• metoclopramide or domperidone (medicines used for nausea and vomiting)
• parasympathomimetics (medicine used for urinary retention) ex. neostigmine, bethanechol

Overdosage:

If you or anyone else accidentally took more MANOHEXY 5MG TABLET, consult your
doctor immediately or visit the nearby hospital. Symptoms of overdose might
include anxiety, depression, and behavioral changes.

Synopsis

Drug	:	Trihexyphenidyl
Pharmacological Category	:	Antimuscarinic agents
Therapeutic Indication	:	Abnormal muscle movements
Dosage Forms	:	Tablet, Injection

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More Information

• Keep MANOHEXY 5MG TABLET out of reach of children
• Store MANOHEXY 5MG TABLET at room temperature

FAQs About MANOHEXY 5MG TABLET

Q: How long does it take for MANOHEXY 5MG TABLET to start acting?

A: MANOHEXY 5MG TABLET begins to act within 1 hour following administration. It
reaches its maximum action between 2-3 hours after administration. The effects
of MANOHEXY 5MG TABLET can be there in your body for around 6-12 hours.

Q: What MANOHEXY 5MG TABLET is used for?

A: MANOHEXY 5MG TABLET is used to improve muscle control in patients with
Parkinson’s disease. It can also be used to control abnormal involuntary muscle
movements (such as extreme restlessness or muscle spasms) in the body that is
caused due to the use of certain medicines.

Q: Is MANOHEXY 5MG TABLET safe to be taken by pregnant and breastfeeding
women?

A: MANOHEXY 5MG TABLET is not recommended for use in pregnant or breastfeeding
women. However, consult your doctor before taking.

Q: What are the side effects of MANOHEXY 5MG TABLET?

A: The most common side effects of taking MANOHEXY 5MG TABLET are dry mouth,
constipation, dizziness, blurring of vision, nausea, and vomiting. Consult your
doctor if any of these symptoms gets worse.

Q: Is it safe to drive after taking MANOHEXY 5MG TABLET?

A: MANOHEXY 5MG TABLET may cause dizziness and blurred vision in some
individuals. If you experience these side effects, try to avoid driving or
operating heavy machines.

Q: What happens if you take more MANOHEXY 5MG TABLET than your required
dose?

A: If you or anyone else accidentally took more MANOHEXY 5MG TABLET, consult
your doctor immediately or visit the nearby hospital. Symptoms of overdose are
anxiety, depression, and behavioral changes.

Q: How long should I take MANOHEXY 5MG TABLET?

A: You are advised to take MANOHEXY 5MG TABLET until your doctor suggests you
discontinue the medicine. Do not stop taking MANOHEXY 5MG TABLET without
consulting your doctor as it may make your symptoms to reappear.

Q: Will taking a higher dose of MANOHEXY 5MG TABLET be more effective?

A: No. Do not take a higher dose of MANOHEXY 5MG TABLET than the prescribed one
without consulting your doctor. Taking a higher dose of MANOHEXY 5MG TABLET may
not be beneficial. Instead, it can cause serious side effects. If the prescribed
dose is not effective for you, consult your doctor. Your doctor may prescribe a
suitable higher dose or suggest an alternative therapy after evaluating your
disease condition.

Q: What should I do if I forget to take a dose of MANOHEXY 5MG TABLET?

A: If your forgot to take a dose of MANOHEXY 5MG TABLET, take it as soon as you
remember. However, if it is time to take the next dose, skip the missed one and
take the regular dose. Do not take a double dose of MANOHEXY 5MG TABLET to
compensate the missed dose.

Q: Can I stop taking MANOHEXY 5MG TABLET once my symptoms subside?

A: No. Do not stop taking MANOHEXY 5MG TABLET without consulting your doctor as
it may cause the symptoms to reappear. Make sure to take MANOHEXY 5MG TABLET for
the stipulated duration recommended by your doctor to achieve the maximum
results.