Macgyl O Suspension 30ml

Introduction About MACGYL O SUSPENSION

MACGYL O SUSPENSION is a combination of Metronidazole and Ofloxacin, which
belong to the group of medicines called Antibiotics. MACGYL O SUSPENSION is used
to manage different kinds of bacterial and parasitic infections (caused by
different kinds of bacteria or parasites), diarrhea (loose, watery stools that
occur more often than usual) and systemic infection (an infection that is in the
bloodstream).

MACGYL O SUSPENSION should be used with caution in patients with liver problems,
kidney problems and heart disease. MACGYL O SUSPENSION is not recommended for
use by pregnant or breastfeeding women. Consult your doctor before taking it.

The most common side effects of MACGYL O SUSPENSION are nausea, headache,
sleeplessness, genital itching in women, dizziness, vaginal inflammation,
diarrhoea and vomiting. Consult your doctor if any of the symptoms worsen.

Uses Of MACGYL O SUSPENSION

• Manage bacterial and parasitic infections
• Manage diarrhea
• Manage systemic infection (an infection that is in the bloodstream)

How MACGYL O SUSPENSION Works

MACGYL O SUSPENSION helps to reduce infections caused by different bacteria or
parasites, whereas Metronidazole works by inhibiting the protein synthesis in
the cells of various bacteria and parasites, which gradually leads to cell
death. Ofloxacin works by managing bacterial growth (DNA replication), which
leads to cell death.

How to use MACGYL O SUSPENSION

Always use MACGYL O SUSPENSION as directed by your physician. Shake well before
use. Do not stop using MACGYL O SUSPENSION without informing your doctor.

Side Effects Of MACGYL O SUSPENSION

Common

• nausea
• headache
• sleeplessness
• genital itching in women
• dizziness
• vaginal inflammation
• diarrhoea
• vomiting

Rare

Stop using MACGYL O SUSPENSION and contact your doctor immediately if you have:

• allergic reaction with symptoms such as swelling of the face, lips, throat or tongue, itching, difficulty breathing, difficulty swallowing
• skin rashes with blistering, peeling or bleeding of the skin around the lips, eyes, mouth, nose and genitals
• serious but very rare side effect is a brain disease (encephalopathy)
• blistering or bleeding of the skin around the eyes, mouth, lips, nose and genitals
• red, scaly widespread rash with bumps under the skin and blisters accomp
• steven johnson syndrome - severe blistering rash where layers of the skin may peel off

How To Manage Side Effects

Nausea / Vomiting:

Take this medicine with or just after meals. Stick to simple meals. Avoid eating
oil-rich or spicy foods. Consult your doctor if the symptom does not improve.

Headache:

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a
pain-relieving balm on the head if required. Do not consume alcohol. Consult
your doctor if the symptom does not improve.

Dizziness:

If you feel dizzy, keep your eyes closed sit or lie down. Do not drive or
operate machinery. Consult your doctor if the symptom does not improve.

Diarrhea:

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated.
Avoid taking any medicine on your own for managing diarrhoea. Consult your
doctor if the symptom does not improve.

Warning & Precautions

!### Pregnancy

MACGYL O SUSPENSION is not recommended for use in pregnant women. Consult your
doctor before using it.

!### Breastfeeding

MACGYL O SUSPENSION is not recommended for use in breastfeeding women. Consult
your doctor before using it.

!### Driving and Using Machines

Do not drive or operate any machines if you feel sleepy or dizzy or could affect
your eyesight after using MACGYL O SUSPENSION. Consult your doctor before using
it.

!### Alcohol

Avoid consum
cause unpleasant side effects such as nausea, vomiting, hot flushes, stomach
pain, very fast or uneven heartbeat and headache. Consult your doctor before
using it.

!### Kidney

MACGYL O SUSPENSION should be used with caution in patients with kidney problems
and patients undergoing kidney dialysis. Consult your doctor before using it.

!### Liver

MACGYL O SUSPENSION should be used with caution in patients with liver problems.
Consult your doctor before using it.

!### Allergy

Do not take MACGYL O SUSPENSION if you are allergic to metronidazole, ofloxacin,
other quinolone antibiotics such as ciprofloxacin or norfloxacin or any of the
other ingredients in this medicine. Consult your doctor before using it.

!### Lungs

MACGYL O SUSPENSION should be used with caution in patients with a lung
transplant. Consult your doctor before using it.

!### Heart Disease

MACGYL O SUSPENSION should be used with caution in patients with heart disease.
Consult your doctor before using it.

Others

Before using MACGYL O SUSPENSION, inform your doctor if you:

• have a disease of the nervous system
• are on hemodialysis
• have a history of joint problems or rheumatoid arthritis
• are suffering from Alzheimer’s disease, seizures, stroke
• have decreased in blood minerals

Use in Pediatrics:

MACGYL O SUSPENSION should be used with caution in children. Consult your doctor
before using it.

Use in Geriatrics:

MACGYL O SUSPENSION should be used with caution. Consult your doctor before
using it.

Interactions

A. Drug-Drug interactions:

Before taking MACGYL O SUSPENSION, inform your doctor if you are taking any of
these medicines:

• warfarin (anticoagulants)
• lithium (used to manage mental illness)
• phenytoin, carbamazepine, phenobarbitone (used to manage epilepsy)
• 5 fluorouracil, busulfan (used to manage cancer)
• ciclosporin (immunosuppressant)
• disulfiram

Overdosage:

If you or anyone else accidentally receive too much of MACGYL O SUSPENSION,
consult your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Metronidazole, Ofloxacin
Pharmacological Category	:	Nitroimidazole antibiotic, Quinolone antibiotic
Therapeutic Indication	:	Bacterial and parasitic infections, diarrhea, systemic infection
Dosage Forms	:	Tablet, Syrup, Suspension, Oral Suspension

More Information

• Keep MACGYL O SUSPENSION out of reach from children
• Store at room temperature

FAQs About MACGYL O SUSPENSION

Can I drive after taking MACGYL O SUSPENSION?

Do not drive or operate any machines if you feel sleepy or dizzy or if it could
affect your eyesight after taking MACGYL O SUSPENSION. Since MACGYL O SUSPENSION
is an antibiotic, it will affect the body’s normal functioning. So, it is
advised not to drive or operate any machinery after taking MACGYL O SUSPENSION.

Can breast-feeding women take MACGYL O SUSPENSION?

A few clinical trial studies show that MACGYL O SUSPENSION passes through the
breast milk from mother to infant while breastfeeding. So, MACGYL O SUSPENSION
is not recommended for breastfeeding women. Consult your doctor before taking
it.

I am presently undergoing kidney dialysis. Can I take MACGYL O SUSPENSION?

MACGYL O SUSPENSION should be used with caution in dialysis patients. Since
dialysis purifies intoxicants and other materials in the blood, MACGYL O
SUSPENSION can also be removed. So, the effect of MACGYL O SUSPENSION might be
reduced. It is better to inform your doctor if you are on dialysis and you are
taking MACGYL O SUSPENSION.

Does MACGYL O SUSPENSION cause vomiting?

Since vomiting is the most common side effect observed for MACGYL O SUSPENSION,
it may cause vomiting. So, eat simple meals and avoid oily or spicy foods and
take this medicine with or just after meals. Consult your doctor if the symptom
does not improve.

How many doses of MACGYL O SUSPENSION can I take in a day?

Take MACGYL O SUSPENSION as advised by your physician. Do not crush or chew the
medicine. Swallow the medicine with a glass of water. Your doctor will determine
the correct dose and duration for you depending on your age, body weight and
disease condition.

Does MACGYL O SUSPENSION cause sleeplessness?

Yes, the use of MACGYL O SUSPENSION may cause sleeplessness. MACGYL O SUSPENSION
may influence the normal sleep cycle, resulting in reduced sleep compared to
normal. So, it is better to make your surroundings comfortable, which can have a
positive influence on sleep (like the room light being dimmed or minimizing
external noises).