Larentine 10mg Tablet 10'S

Introduction About LARENTINE 10MG TABLET

LARENTINE 10MG TABLET contains Memantine which belongs to the group of medicines
called Anti-dementia drugs. It is used to manage moderate to severe Alzheimer’s
disease. Alzheimer’s disease is a neurodegenerative disease that destroys memory
and other important mental functions in an individual. It is caused due to
formation and accumulation of certain toxic proteins in the brain that destroys
brain cells. It can be characterized by loss of memory and forgetfulness of
day-to-day activities.

Memantine is a N-methyl-D-aspartate (NMDA) receptor antagonist. It acts by
blocking the over activation of certain chemicals (glutamate and beta-amyloid
pe
activity of other chemical messengers (like serotonin and acetylcholine) which
are responsible for affecting thoughts, memory and mental state.

Before taking LARENTINE 10MG TABLET, inform your doctor if you have any liver,
kidney or heart problems. You must also inform your doctor if you have or have a
family history of fits or if you made any sudden changes to your diet. During
management with LARENTINE 10MG TABLET, your doctor would closely monitor your
health condition to access the improvement and to avoid unwanted side effects.

LARENTINE 10MG TABLET should not be used in pregnant or breastfeeding women. It
is also not suitable for use in children aged below 18 years. It should be used
with caution in the elderly patients.

The most common side effects of taking LARENTINE 10MG TABLET are headache,
dizziness, sleepiness and constipation. Consult your doctor if they trouble you.
Also, inform your doctor if you unusually feel sad or depressed with suicidal
thoughts after taking LARENTINE 10MG TABLET.

Uses Of LARENTINE 10MG TABLET

• Manage moderate to severe Alzheimer’s disease

How LARENTINE 10MG TABLET Works

LARENTINE 10MG TABLET is a NMDA receptor antagonist. It acts by blocking the
over activation of certain chemicals (glutamate and beta-amyloid pe
the brain that causes Alzheimer’s disease. It can also block the activity of
other chemical messengers (like serotonin and acetylcholine) that affects
thoughts, memory and mental state. As a result, it improves memory and
stabilizes mental health.

How to use LARENTINE 10MG TABLET

Take LARENTINE 10MG TABLET as advised by your doctor. It can be taken with or
without meals.  Swallow the medicine with a glass of water. Do not crush or chew
the medicine. Try to take the medicine at the same time each day. Your doctor
will decide the correct dose and duration of therapy for you depending upon your
age, body weight and disease condition. Do not stop taking LARENTINE 10MG TABLET
without consulting your doctor.

Side Effects Of LARENTINE 10MG TABLET

Common

• headache, dizziness
• sleepiness
• constipation
• balance disorders
• shortness of breath
• high blood pressure

Uncommon

• tiredness
• fungal infections
• confusion
• hallucinations
• vomiting
• abnormal manner of walking
• heart failure
• formation of blood clots

Rare

Stop taking LARENTINE 10MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• depression or thoughts of harming or killing yourself (suicidal ideation)

How To Manage Side Effects

Headache:

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as
water or electrolytes. Applying a pain-relieving balm on your forehead can be
beneficial. Do not consume excessive alcohol, as it could aggravate your
headache. Consult your doctor if your headache worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or
machines completely while you are feeling dizzy. Consult your doctor if your
dizziness worsens.

Constipation:

Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals.
Drink plenty of fluids. Exercise more regularly. Consult your doctor if this
side effect bothers you.

Warning & Precautions

!### Pregnancy

LARENTINE 10MG TABLET is not recommended for use in pregnant women. Therefore,
consult your doctor before taking it.

!### Breastfeeding

LARENTINE 10MG TABLET is not recommended for use in breast feeding women.
Therefore, consult your doctor before taking it.

!### Driving and Using Machines

Do not drive or operate heavy machines if your ability is affected by LARENTINE
10MG TABLET.

!### Alcohol

Avoid consum
you feel dizzy or drowsy.

!### Kidney

LARENTINE 10MG TABLET should be used with caution in patients with kidney
problems (such as renal tubulary acidosis, severe infections of the urinary
tract or have problem in passing urine). Therefore, consult your doctor before
taking it.

!### Liver

LARENTINE 10MG TABLET should be used with caution in patients with liver
problems (such as jaundice or liver failure). Therefore, consult your doctor
before taking it.

!### Allergy

Do not take LARENTINE 10MG TABLET if you are allergic to Memantine.

!### Heart Disease

LARENTINE 10MG TABLET should be used with caution in patients with heart
problems (such as congestive heart failure, uncontrollable high blood pressure
or a recent heart attack). Therefore, consult your doctor before taking it.

Others

Before taking LARENTINE 10MG TABLET, inform your doctor if you have:

• a history of epilepsy

Use in pediatrics

LARENTINE 10MG TABLET is not recommended for use in children and adolescents
(below 18 years). Therefore, consult your doctor before taking it.

Use in geriatrics

LARENTINE 10MG TABLET should be used with caution in elderly patients (65 years
and above). Therefore, consult your doctor before taking it.

Interactions

A. Drug-Drug interactions

Before taking LARENTINE 10MG TABLET, inform your doctor if you are taking any of
the following medicines such as:

• amantadine (a medicine used to manage viral infections or Parkinson’s disease)
• ketamine (a medicine used as an anesthetic)
• dextromethorphan (a medicine used to manage cough)
• medicine used to manage muscle spasms or spasticity (Ex. dantrolene, baclofen)
• medicine used to manage stomach ulcers (Ex. cimetidine, r
• medicine used to manage abnormal heart rhythm (Ex. quinidine, procainamide, amiodarone, flecainide)
• medicine used to manage malaria (Ex. quinine)
• medicine used to increase urine output (Ex. hydrochlorothiazide)
• anticholinergics (used to manage movement disorders or intestinal cramps) such as atropine, scopolamine, glycopyrrolate
• medicine used to manage epilepsy (Ex. carbamazepine, gabapentin)
• medicine used to induce sleep such as barbiturates (Ex. phenobarbital)
• medicines used in the management of mental disorders such as neurole
• medicines used for blood clotting (Ex. warfarin, rivaroxaban)
• dopaminergic agonists (used to relieve conditions related to low levels of dopamine such as Parkinson's disease or restless legs syndrome) Ex. L-dopa, bromocri
• nicotine (a medicine used for smoking cessation)
• carbonic anhydrase inhibitors (used to increase urine output) Ex. acetazolamide

B. Drug - Food interactions

Consult your doctor if you have recently changed your diet (Ex. from normal diet
to strict vegetarian diet) as there may be a need for dose adjustments.

Overdosage

If you or anyone else accidentally took more LARENTINE 10MG TABLET, consult your
doctor immediately or visit the nearby hospital. Symptoms of overdose might
include feeling tired, slow heart rate, confusion, dizziness, increased blood
pressure, feeling faint, psychosis, feeling agitated, restless or sleepy, slowed
movement, unsteady movements, hallucinations, sensation of spinning and
vomiting.

Synopsis

Drug	:	Memantine
Pharmacological Category	:	N-methyl-D-aspartate (NMDA) receptor antagonist
Therapeutic Indication	:	Alzheimer’s disease
Dosage Forms	:	Tablet

More Information

• Keep LARENTINE 10MG TABLET out of reach of children
• Store LARENTINE 10MG TABLET at room temperature

FAQs About LARENTINE 10MG TABLET

Is LARENTINE 10MG TABLET addictive in nature?

No. LARENTINE 10MG TABLET is not addictive in nature. However, consult your
doctor if you experience any unusual withdrawal symptoms.

How and when LARENTINE 10MG TABLET should be taken?

Take LARENTINE 10MG TABLET as advised by your doctor. It can be taken with or
without meals.  Swallow the medicine with a glass of water. Do not crush or chew
the medicine. Try to take LARENTINE 10MG TABLET at the same time each day. Your
doctor will decide the time of administration and number of doses per day
depending upon your age, body weight and disease condition. Do not stop taking
LARENTINE 10MG TABLET without consulting your doctor.

Can LARENTINE 10MG TABLET manage dementia?

LARENTINE 10MG TABLET can manage dementia which is caused due to Alzheimer’s
disease. However, consult your doctor before taking it.

How long should I use LARENTINE 10MG TABLET to see the results?

Take LARENTINE 10MG TABLET until your doctor advises you to stop. Research shows
that it may take around 6 months for LARENTINE 10MG TABLET to show results in
the affected patients. However, this period may not be the same for everyone. It
differs from patient-to-patient depending upon the severity of the disease.
Therefore, consult your doctor for advice.

Can LARENTINE 10MG TABLET be used to enhance memory in children?

No. LARENTINE 10MG TABLET is not a memory enhancer. It only manages the
destruction of brain cells that carries memories in the aging people. It is not
suitable for use in children and adolescents (under 18 years) to enhance memory.

Can I stop taking LARENTINE 10MG TABLET without consulting the doctor once I
feel better?

Do not stop taking LARENTINE 10MG TABLET without consulting your doctor. There
is no manage for Alzheimer’s disease. Medicines are available only to manage its
symptoms, and so discontinuation of the therapy may make your symptoms to
reappear once again. However, if you feel that your symptoms have disappeared,
consult your doctor for advice. Your doctor will carefully evaluate your health
condition before stopping the therapy.

Can LARENTINE 10MG TABLET make me feel sleepy?

Yes. LARENTINE 10MG TABLET may make you feel sleepy. If you feel sleepy, rest,
and relax. Restrict yourself from doing activities that may put you in danger.
Avoid driving or handling heavy tools or machines. Consult your doctor if this
side effect bothers you.

What medicines should be avoided while taking LARENTINE 10MG TABLET?

Before taking LARENTINE 10MG TABLET it is important for you to inform your
doctor about the use of other medicines that can make you feel more sleepy or
drowsy such as ketamine, dextromethorphan, carbamazepine, or phenobarbital. You
must also inform your doctor if you have any heart problems, mental disorders,
stomach problems or muscle problems and taking medicines to manage the same
(such as thioridazine, chlorpromazine, thiothixene, dantrolene, baclofen,
cimetidine, r

What happens when LARENTINE 10MG TABLET is taken along with
hydrochlorothiazide?

Avoid taking LARENTINE 10MG TABLET with hydrochlorothiazide as it may reduce the
effectiveness of LARENTINE 10MG TABLET. Inform your doctor if you are already
taking hydrochlorothiazide before starting therapy with LARENTINE 10MG TABLET.

Can LARENTINE 10MG TABLET be taken along with donepezil?

Studies have shown better results in management of Alzheimer’s disease when
LARENTINE 10MG TABLET is combined with donepezil. However, consult your doctor
for advice.

Can LARENTINE 10MG TABLET be used in pregnant women?

LARENTINE 10MG TABLET is not recommended for use in pregnant women and in those
who are planning to become pregnant. Therefore, consult your doctor before
taking it.

Can LARENTINE 10MG TABLET cause headaches?

Yes. LARENTINE 10MG TABLET may cause headache in some individuals. In case of
you are experiencing a headache after taking LARENTINE 10MG TABLET, try to rest
and relax. Drink plenty of fluids such as water or electrolytes. Apply a
pain-relieving balm on your forehead if needed. Do not consume too much of
alcohol. Consult your doctor if your headache persists for a long time.

Can I use LARENTINE 10MG TABLET without consulting a doctor?

No. LARENTINE 10MG TABLET should be used only under medical supervision. Your
doctor will decide the correct dose and duration of therapy for you depending
upon your age, body weight and severity of the disease. Do not take LARENTINE
10MG TABLET without consulting your doctor.

What can be done if I forget to take a dose of LARENTINE 10MG TABLET?

If you forget to take a dose of LARENTINE 10MG TABLET take it as soon as you
remember. However, skip the missed dose if it is time for the next dose. Do not
take a double dose to make up for a forgotten dose.