Lapezil 10mg Tablet 10'S

Introduction About LAPEZIL 10MG TABLET

LAPEZIL 10MG TABLET contains Donepezil which belongs to the group of medicines
called Cholinesterase inhibitors. It is indicated for the management of mild to
moderately severe Alzheimer’s dementia.

Alzheimer's disease is a brain disorder that causes dementia (a group of
symptoms that affect the memory, thinking and social abilities of a person) by
destroying the memory and other important mental functions in the brain which is
characterized by memory loss, confusion, and behavioral changes.

Before taking LAPEZIL 10MG TABLET, inform your doctor if you are allergic to
Donepezil, have asthma, heart, kidney, or liver disease.

LAPEZIL 10MG TABLET is not recommended for use if you have severe liver disease.
Consult your doctor before taking medicine.

LAPEZIL 10MG TABLET is generally not recommended for use in pregnant and
breastfeeding women unless it is considered clearly necessary. Consult your
doctor before taking LAPEZIL 10MG TABLET.

The safety and effectiveness of LAPEZIL 10MG TABLET in pediatric patients have
not been established.

The most common side effects of taking LAPEZIL 10MG TABLET are diarrhoea,
feeling sick, tiredness, difficulty in sleeping, common cold, loss of appetite,
hallucinations, and aggressive behaviour. Consult your doctor if any of these
above side effects get worse.

Uses Of LAPEZIL 10MG TABLET

• Used to manage mild to moderately severe Alzheimer’s dementia

How LAPEZIL 10MG TABLET Works

LAPEZIL 10MG TABLET belongs to cholinesterase inhibitor which works by
increasing the levels of a chemical messenger (acetylcholine) involved in
transmission of nerve signals. This improves memory and thinking. Memory loss in
Alzheimer’s disease occurs due to disturbances of signal transmission in the
brain.

How to use LAPEZIL 10MG TABLET

Take LAPEZIL 10MG TABLET as advised by your physician. Swallow LAPEZIL 10MG
TABLET with a glass of water and do not chew or crush the medicine. Your doctor
will decide the correct dose and duration for you depending upon your age, body
weight and disease condition.

Side Effects Of LAPEZIL 10MG TABLET

Common

• diarrhea
• nausea
• headache
• muscle cramp
• tiredness
• difficulty in sleeping (insomnia)
• common cold
• loss of appetite
• hallucinations
• unusual dreams including nightmares
• agitation
• aggressive behaviour
• fainting, dizziness
• indigestion
• vomiting
• rash, itching
• passing urine uncontrollably
• pain

Uncommon

• slow heartbeat

Rare

• uncontrollable or shaky movements with stiffness on the face and tongue which may also involve limbs
• irregular heartbeats

Stop taking LAPEZIL 10MG TABLET and contact your doctor if you experience any of
the following side effects:

• signs of stomach or duodenal ulcers such as stomach pain and indigestion
• signs of bleeding in the stomach or intestines such as passing black tar like stools or visible blood from the rectum
• seizures (fits) or convulsions
• signs of hepatitis (liver damage) such as feeling or being sick, loss of appetite, feeling unwell, fever, itching, yellowing of the skin and eyes, and dark coloured urine
• signs of a neurole
• signs of rhabdomyolysis such as muscle weakness, tenderness or pain, particularly, if at the same time, you feel unwell, have a high temperature or have dark urine

How To Manage Side Effects

!### Diarrhea

Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid
taking any medicine on your own to manage diarrhea and consult your doctor if
the symptom gets worse.

!### Dizziness Or Drowsiness

Try to rest and relax and get enough sleep. Try to avoid driving or operating
any tools or machines while you are feeling dizzy. Limit your consum
alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom
does not improve.

!### Indigestion

Try to reduce your consum
if you are obese. Avoid smoking and do not eat three to four hours before going
to bed. Consult your doctor if the symptom does not improve.

!### Nausea And Vomiting

Try to take LAPEZIL 10MG TABLET with or just after a meal or a snack. Stick to
simple meals. Avoid eating rich or spicy food. Consult your doctor if the
symptom gets worse.

!### Tiredness

Make sure you take rest and drink plenty of fluids. Avoid or limit the
consum
sit down (or lie down) when the symptoms are at their worst. Try not to drive or
use tools or machinery until you feel well.

Warning & Precautions

!### Pregnancy

Monitoring requiredLAPEZIL 10MG TABLET is generally not recommended for use during pregnancy unless
it is considered clearly necessary. Consult your doctor before taking LAPEZIL
10MG TABLET.

!### Breastfeeding

ContraindicatedLAPEZIL 10MG TABLET is not recommended for use in breastfeeding women. Consult
your doctor before taking LAPEZIL 10MG TABLET.

!### Driving and Using Machines

Use with CautionLAPEZIL 10MG TABLET may cause tiredness, dizziness and muscle cramp which could
affect your ability to drive or operate machines. If you experience these side
effects, do not drive or operate machines. Consult your doctor before taking
LAPEZIL 10MG TABLET.

!### Alcohol

Consult your doctorAvoid consum
alter the effect of this medicine.

!### Kidney

Use with CautionLAPEZIL 10MG TABLET should be used with caution in patients with mild kidney
disease. Consult your doctor before taking LAPEZIL 10MG TABLET.

!### Liver

Consult your doctorLAPEZIL 10MG TABLET is not recommended for use in patients with severe liver
disease. It should be used with caution in patients with liver problems or
hepatitis. Consult your doctor before taking LAPEZIL 10MG TABLET.

!### Allergy

ContraindicatedDo not take LAPEZIL 10MG TABLET if you are allergic to Donepezil or piperidine
derivatives such as haloperidol, thioridazine, or any of the other ingredients
of this medicine.

!### Lungs

Use with CautionLAPEZIL 10MG TABLET should be used with caution in patients with asthma or
long-term lung disease. Consult your doctor before taking LAPEZIL 10MG TABLET.

!### Heart Disease

Use with CautionLAPEZIL 10MG TABLET should be used with caution in patients with heart diseases
such as irregular or very slow heartbeat, fast heartbeat, abnormal heart
rhythms, family history of prolonged QT interval (fast and chaotic heartbeats),
had heart failure, or heart attack. Consult your doctor before taking LAPEZIL
10MG TABLET.

!### Use In Pediatrics

Consult your doctorThe safety and effectiveness of LAPEZIL 10MG TABLET in pediatric patients have
not been established. Consult your doctor before taking LAPEZIL 10MG TABLET.

!### Use In Geriatrics

Use with CautionLAPEZIL 10MG TABLET should be used with caution in elderly patients (aged 65
years above). Consult your doctor before taking LAPEZIL 10MG TABLET.

Others

Before taking LAPEZIL 10MG TABLET, inform your doctor if you:

• have low levels of magnesium or potassium in your blood
• have difficulty passing urine
• have stomach or duodenal ulcers
• have seizures (fits) or convulsions

Interactions

A. Drug-Drug Interactions:

Before taking LAPEZIL 10MG TABLET, inform your doctor, if you are taking any of
the following medicine:

• Anti-arrhythmics (Ex. amiodarone, sotalol)
• Antidepressants (Ex. citalopram, escitalopram, amitriptyline, fluoxetine)
• Antipsychotics (Ex. pimozide, sertindole, ziprasidone)
• Antibiotics (Ex. clarithromycin, erythromycin, levofloxacin, moxifloxacin, rifampicin)
• Anti-fungal agents (Ex. ketoconazole)
• other medicines used to manage Alzheimer’s disease (Ex. galantamine)
• medicines used for arthritis (Ex. aspirin, non-steroidal anti-inflammatory (NSAID) drugs such as ibuprofen, or diclofenac sodium)
• anticholinergics medicines (Ex. tolterodine)
• anticonvulsants (Ex. phenytoin, carbamazepine)
• Cardiac drugs (Ex. quinidine, beta-blockers such as propanolol and atenolol)
• muscle relaxants (Ex. diazepam, succinylcholine)
• general anesthetics (Ex. propofol, ketamine, thiopental)
• medicines obtained without a prescri

Overdosage:

If you or anyone else accidentally takes too much of LAPEZIL 10MG TABLET,
consult your doctor immediately or visit the nearby hospital. Symptoms of
overdose are feeling and being sick, drooling, sweating, slow heart rate, low
blood pressure (lightheadedness or dizziness when standing), breathing problems,
losing consciousness and seizures (fits) or convulsions.

Synopsis

Drug	:	Donepezil
Pharmacological Category	:	Acetyl cholinesterase Inhibitor
Therapeutic Indication	:	Alzheimer disease
Dosage Forms	:	Tablet, Syrup, Orally disintegrating strips

More Information

Storage

• Keep the medicine out of reach in children
• Store LAPEZIL 10MG TABLET at room temperature

FAQs About LAPEZIL 10MG TABLET

Q: Can LAPEZIL 10MG TABLET cure Alzheimer's disease?

A: No, LAPEZIL 10MG TABLET does not cure Alzheimer's disease. It helps to manage
symptoms and may improve cognitive function in some patients.

Q: Can I stop taking LAPEZIL 10MG TABLET suddenly?

A: You should not stop taking LAPEZIL 10MG TABLET suddenly without consulting
your doctor. Abruptly stopping the medication may cause a worsening of symptoms.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it’s almost time for
your next dose, skip the missed dose. Do not take two doses at the same time to
make up for a missed dose.

Q: Can LAPEZIL 10MG TABLET interact with other medications?

A: Yes, LAPEZIL 10MG TABLET can interact with other medications. It's important
to inform your doctor about all the medications you are taking, including
over-the-counter drugs, vitamins, and herbal supplements.

Q: Is there a need for regular monitoring while on LAPEZIL 10MG TABLET?

A: Yes, your doctor may monitor your progress regularly to ensure the medication
is working effectively and to check for any adverse effects.

Q: What LAPEZIL 10MG TABLET is used for?

A: LAPEZIL 10MG TABLET is indicated for the management of mild to moderately
severe Alzheimer’s dementia.

Q: For how long should I take LAPEZIL 10MG TABLET?

A: Your doctor might advise you on how long you should continue to take LAPEZIL
10MG TABLET. You will need to consult your doctor from time to time to review
your management and assess your symptoms.

Q: What happens if you take more LAPEZIL 10MG TABLET than your required dose?

A: If you or anyone else accidentally takes too much of LAPEZIL 10MG TABLET,
consult your doctor immediately or visit the nearby hospital. Symptoms of
overdose are feeling and being sick, drooling, sweating, slow heart rate, low
blood pressure (lightheadedness or dizziness when standing), breathing problems,
losing consciousness and seizures (fits) or convulsions.

Q: What side effects are seen with LAPEZIL 10MG TABLET?

A: The most common side effects of taking LAPEZIL 10MG TABLET are diarrhoea,
feeling sick, tiredness, difficulty in sleeping, common cold, loss of appetite,
hallucinations, and aggressive behavior. Consult your doctor if any of these
symptoms gets worse. Consult your doctor if any of these symptoms gets worse.

Q: Is it safe to drive after taking LAPEZIL 10MG TABLET?

A: LAPEZIL 10MG TABLET may cause tiredness, dizziness and muscle cramp which
could affect your ability to drive or operate machines. If you experience these
side effects, do not drive or operate machines. Consult your doctor before
taking LAPEZIL 10MG TABLET.