Lantus Optiset 100IU Pen(Prefilled) 1X3ml

Introduction About LANTUS O

LANTUS O
the group of medicines called Antidiabetics. It is used in adults to manage
diabetes mellitus, a disease where the body does not produce enough insulin to
control the level of blood sugar, resulting in high blood sugar levels. Symptoms
include increased thirst, frequent urination, extreme hunger, unexplained weight
loss, fatigue, irritability, blurred vision, slow-healing sores, frequent
infections, and increased ketone levels in urine.

Your doctor might want you to make certain lifestyle changes, like eating a
healthy diet, not skipping meals, maintaining your weight, quitting alcohol and
smoking, and exercising regularly. Before management, your doctor might want to
take certain blood tests to understand your existing condition.

Before receiving LANTUS O
have low blood sugar, kidney, liver, or heart problems, or diabetic
ketoacidosis. Avoid drinking alcohol while receiving LANTUS O
PEN(PREFILLED). Inform your doctor if you are pregnant or breastfeeding before
receiving LANTUS O
LANTUS O

The most common side effects of receiving LANTUS O
are low blood sugar (hypoglycemia), weight gain, and allergic reactions,
including reactions at the injection site. If your symptoms do not improve, see
your doctor.

Uses Of LANTUS O

• To manage diabetes mellitus in adults

How LANTUS O

LANTUS O
increased protein synthesis and uptake of glucose, following the binding of
insulin to receptors on muscle and fat cells and then inhibiting glucose output
from the liver.

How to use LANTUS O

LANTUS O
nurse under the skin (subcutaneously, usually thighs, upper arm, or abdomen).
Your doctor will decide the right dose and duration depending on your age, body
weight, and disease condition.

Side Effects Of LANTUS O

Common

• low blood sugar (hypoglycemia)
• weight gain
• allergic reactions to skin
• skin thickening or pits at the injection site (lipodystrophy)

Stop receiving LANTUS O
immediately if you experience any of the following side effects:

• severe low blood sugar (hypoglycemia) (showing symptoms of dizziness or light-headedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability or mood change, and hunger)
• severe allergic reaction (whole body reaction, a rash over your whole body, trouble breathing, a fast heartbeat, or sweating)
• low potassium in your blood (hypokalemia)
• heart failure (symptoms of shortness of breath, swelling of your ankles or feet, sudden weight gain)
• trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, and confusion

Warning & Precautions

!### Pregnancy

Consult your doctorIf you are pregnant, think you may be pregnant, or are planning to have a baby,
ask your doctor for advice before receiving LANTUS O
as it is unknown if it will harm the unborn baby. It will be given only if the
benefits outweigh the risk to the fetus and mother.

!### Breastfeeding

Use with CautionLANTUS O
women as it is not known if it is excreted in breast milk. Inform your doctor
before receiving this, and the dose will be adjusted by your doctor.

!### Driving and Using Machines

Use with CautionDo not drive or use machines while receiving LANTUS O
PEN(PREFILLED), as your blood sugar can be low or high and your concentration
and ability to react might be affected. Consult your doctor if you have frequent
episodes of hypoglycemia.

!### Alcohol

Consult your doctorAvoid consum
PEN(PREFILLED), as it can raise or lower your blood sugar levels.

!### Kidney

Use with CautionLANTUS O
kidney disease. Your dose will be adjusted depending on your age, body weight,
and disease condition. Consult your doctor before receiving LANTUS O
PEN(PREFILLED).

!### Liver

Use with CautionLANTUS O
liver disease. Your dose will be adjusted depending on your age, body weight,
and disease condition. Consult your doctor before receiving it.

Allergy

ContraindicatedBefore receiving LANTUS O
are allergic to insulin, glargine, or any of the other ingredients in this
medicine.

!### Heart Disease

Use with CautionLANTUS O
heart failure, stroke, or other heart problems. Consult your doctor before
receiving LANTUS O

!### Use In Pediatrics

Consult your doctorThe safety and effectiveness of LANTUS O
have not been established yet. Consult your doctor before receiving it.

!### Use In Geriatrics

Use with CautionLANTUS O
65 years of age. The dose will be adjusted, and regular blood and kidney tests
will be conducted. Consult your doctor before receiving LANTUS O
PEN(PREFILLED).

Others

LANTUS O

• have diabetic ketoacidosis
• had an episode of low blood sugar

Interactions

A. Drug-Drug interactions:

Before receiving LANTUS O
are taking any of the following medicines:

• other medicines for the management of diabetes (metformin, repaglinide, glucagon, pioglitazone, etc.)
• monoamine oxidase inhibitors (MAOI) (used to manage depression) (phenelzine, selegiline)
• medicines used to manage high blood pressure and heart conditions Ex. metoprolol, atenolol, clonidine, guanethidine, reserpine, chlorothiazide, diazoxide, benazepril, captopril, disopyramide
• salicylates (used to relieve pain and lower fever) (aspirin, pentoxifylline, propoxyphene)
• sulphonamides (used to manage infections) (Ex. bactrim, cotrim)
• oral contrace
• somatostatin analogues (Ex. octreotide)
• glucocorticoids (such as ‘cortisone’ used to manage inflammation)
• thyroid hormones (used to manage thyroid gland disorders)
• growth hormone (medicine for stimulation of skeletal and somatic growth and pronounced influence on the body’s metabolic processes like somatropin)
• danazol (a medicine acting on ovulation)
• niacin used to manage cholesterol levels
• fluoxetine (used to manage depression)
• fibrates (used to lower high levels of blood lipids)
• diuretics (used to manage high blood pressure or excessive fluid retention)
• glucagon (a pancreatic hormone used to manage severe hypoglycemia)
• isoniazid (used to manage tuberculosis)
• phenothiazine derivatives, lithium salts (used to manage psychiatric disorders), and atypical antipsychotic medicines (such as olanzapine and clozapine)
• sympathomimetic medicines (such as epinephrine, salbutamol, and terbutaline used to manage asthma)
• protease inhibitors Ex. darunavir, indinavir (used to manage HIV)
• pentamidine (used to manage some infections caused by parasites)

Overdosage:

LANTUS O
or a nurse in a hospital, so it is unlikely to receive an overdose. However,
consult your doctor or nurse if you experience any unusual symptoms of low blood
sugar or hypokalemia (low potassium levels in the blood)

Synopsis

Drug	:	Insulin glargine
Pharmacological Category	:	Antidiabetic
Therapeutic Indication	:	Diabetes mellitus
Dosage Forms	:	Injection, Cartridge, Kit, Prefilled pen, Prefilled syringes

More Information

• Keep LANTUS O
• Store in a refrigerator (2-8°C)

FAQs About LANTUS O

Q: What is LANTUS O

A: LANTUS O
adults, a disease where the body does not produce enough insulin to control the
level of blood sugar, resulting in high blood sugar levels.

Q: What should I do if I experience low blood sugar during management with LANTUS O

A: Take glucose tablets or high-sugar snacks (sweets, biscuits, fruit juice) if
you experience low blood sugar while taking LANTUS O
Measure your blood sugar and rest. Carry glucose tablets or sugar snacks with
you in case of emergencies.

Q: Can I receive LANTUS O

A: If you are pregnant, think you may be pregnant, or are planning to have a
baby, ask your doctor for advice before receiving LANTUS O
PEN(PREFILLED), as it is unknown if it will harm the unborn baby. It will be
given only if the benefits outweigh the risks to the fetus and mother.

Q: Can LANTUS O

A: LANTUS O
with liver and kidney disease. Your dose will be adjusted depending on your age,
body weight, and disease condition. Consult your doctor before receiving it.

Q: How does LANTUS O

A: LANTUS O
facilitated uptake of glucose following the binding of insulin to receptors on
muscle and fat cells, inhibiting glucose output from the liver. Your doctor
might also want you to make certain lifestyle changes, like eating a healthy
diet, not skipping meals, maintaining your weight, quitting alcohol and smoking,
and exercising regularly.

Useful Diagnostic Tests

• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
• Blood Glucose Fasting (FBS)
• Random Blood Sugar (RBS)
• Post Prandial Blood Sugar (PPBS)
• Insulin-Fasting
• Insulin Postprandial (PP)
• Vital Diabetes Care
• Extended Diabetes Care
• Advance Diabetes Care
• Comprehensive Diabetes Care