Kinocin Tablet 10'S

Introduction About KINOCIN TABLET

KINOCIN TABLET contains Cinitapride which belongs to the group of medicines
called Gastro-prokinetic agents. KINOCIN TABLET is used to manage
gastroesophageal reflux disease and functional gastrointestinal motility
disorders (disease marked by persistent and recurring gastrointestinal symptoms)
in affected individuals.

KINOCIN TABLET is not recommended for use in patients allergic to Cinitapride.
It is also not recommended for use in patients with gastrointestinal
bleeding/obstruction/perforation and in patients with a history of
neurole
movements of head, neck, trunk or limbs).

Before taking KINOCIN TABLET, inform your doctor if you have intolerance to
certain sugars (such as lactose), liver disease (such as primary/secondary liver
tumors, hepatocellular carcinoma) and/or kidney disease (such as acute renal
injury/failure).

KINOCIN TABLET is not recommended for use in pregnant and breastfeeding women.
It is also not recommended for use in children & adolescents (aged below 18
years) and is advised to be used with caution in elderly patients (aged 65
years/above) after consulting the doctor.

The most common side effects of taking KINOCIN TABLET are abdominal discomfort,
nausea and/or diarrhea. Consult your doctor if any of these symptoms worsen.

Uses Of KINOCIN TABLET

• Manage gastroesophageal reflux disease
• Manage functional gastrointestinal motility disorders in affected individuals

How KINOCIN TABLET Works

KINOCIN TABLET works by increasing the gastrointestinal movement by enhancing
the frequency and strength of stomach muscle contractions which leads to
increased gastric motility & emptying thus improving gastro-duodenal
coordination and managing the occurrence of gastroesophageal reflux disease in
affected individuals.

How to use KINOCIN TABLET

Take KINOCIN TABLET as advised by your physician. Swallow the medicine with a
glass of water. Do not crush or chew the medicine. Your doctor will decide the
correct dose and duration for you depending upon your age, body weight and
disease condition.

Side Effects Of KINOCIN TABLET

Common

• abdominal discomfort
• diarrhea
• nausea

Rare

• signs of allergic skin reactions such as rash, itching
• gynecomastia (swelling of male breast tissue)
• angioedema (swelling under the skin)
• spasm in the muscles of face, neck and tongue

How To Manage Side Effects

Nausea and vomiting:

Try to take KINOCIN TABLET with or just after a meal or a snack. Stick to simple
meals. Avoid eating rich or spicy food. Consult your doctor if symptom gets
worse.

Diarrhea:

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on
your own to manage diarrhea. Consult your doctor and inform them if the symptom
gets worse.

Warning & Precautions

!### Pregnancy

KINOCIN TABLET is not recommended for use in pregnant women. Consult your doctor
before taking the medicine.

!### Breastfeeding

KINOCIN TABLET is generally not recommended for use in breastfeeding women.
Consult your doctor before taking the medicine.

!### Driving and Using Machines

Do not drive or use heavy machinery while taking KINOCIN TABLET as it may affect
your ability to drive or use heavy machinery.

!### Alcohol

Avoid consum
enhance the sedative effects of the medicine.

!### Kidney

KINOCIN TABLET should be used with caution in patients with kidney diseases such
as acute renal injury/failure. Consult your doctor before taking the medicine.

!### Liver

KINOCIN TABLET should be used with caution in patients with liver diseases such
as primary/secondary liver tumors, hepatocellular carcinoma. Consult your doctor
before taking the medicine.

!### Allergy

Do not take KINOCIN TABLET if you are allergic to cinitapride or any of the
other ingredients of this medicine. Consult your doctor before taking the
medicine.

Others

KINOCIN TABLET is not recommended for use if you have:

• gastrointestinal bleeding, obstruction or perforation with stimulating gastric motility
• history of neurole

Before taking KINOCIN TABLET, inform your doctor if you:

• intolerance to certain sugars such as lactose

Use in Pediatrics:

KINOCIN TABLET is not recommended for use in children and adolescents (aged
below 18 years). Consult your doctor before taking the medicine.

Use in Geriatrics:

KINOCIN TABLET should be used with caution in elderly patients (aged above 65
years) especially with type 2 diabetes. Consult your doctor before taking the
medicine.

Interactions

A. Drug - Drug interactions:

Before taking KINOCIN TABLET, inform your doctor if you are taking:

• phenothiazine (used to manage serious mental and emotional disorders)
• other antidopaminergic drugs (used as a non-addictive alternative to manage withdrawal, agitation and anxiety in patients with alcohol dependence) Ex. risperidone, olanzapine
• digoxin (used to manage heart failure)
• anticholinergic drugs (used to manage various conditions such as urinary incontinence, overactive bladder, asthma, diarrhea, motion sickness) Ex. atropine, clidinium, cyclopentolate
• opioid analgesics (used to relieve moderate or intense pain) Ex. codeine, fentanyl
• medicine used to manage nervous system diseases, insomnia. Ex. amitriptyline
• medicine used to manage Parkinson’s disease (Ex. levodopa)
• medicine used to manage abdominal pain (Ex. ibuprofen)
• medicine used to manage respiratory disease such as chronic bronchitis. (Ex. albuterol)

Overdosage:

If you or anyone else accidentally took too much of KINOCIN TABLET, consult your
doctor immediately or visit the nearby hospital. Symptoms of overdose include
drowsiness, disorientation and/or extrapyramidal reactions (such as involuntary
muscle movements of face, neck and tongue).

Synopsis

Drug	:	Cinitapride
Pharmacological Category	:	Pro-kinetic drug
Therapeutic Indication	:	Gastroesophageal reflux disease, Functional gastrointestinal motility disorders
Dosage Forms	:	Tablet

More Information

• Keep KINOCIN TABLET out of reach of children
• Store the medicine below 30°C

FAQs About KINOCIN TABLET

What are the side effects of KINOCIN TABLET?

The most common side effects of taking KINOCIN TABLET are abdominal discomfort,
diarrhea and nausea. Contact your doctor if any of these symptoms worsen or
needs immediate care.

How much dose can KINOCIN TABLET be taken in a day?

Take KINOCIN TABLET as advised by your physician. Do not crush or chew the
medicine. Swallow the medicine with a glass of water. Your doctor will decide
the correct dose and duration for you depending upon your age, body weight and
disease condition.

Does KINOCIN TABLET cause diarrhea?

Yes, KINOCIN TABLET causes diarrhea as it is the most common side effect
associated with the use of KINOCIN TABLET. If you experience any such effect,
then try to drink lots of fluids such as water/fruit juices to keep yourself
hydrated and avoid taking any medicine on your own to manage the condition.
Consult your doctor if the symptom does not improve.

Can KINOCIN TABLET be used in children?

No, KINOCIN TABLET is not recommended for use in children and adolescents (aged
below 18 years). If KINOCIN TABLET is accidentally ingested by a child or
adolescent, go to the hospital immediately and consult the doctor for further
management.

Is it safe to use KINOCIN TABLET in pregnant and breastfeeding women?

No, KINOCIN TABLET is not recommended to be used during pregnancy as a
precautionary measure which is also not recommended to be used in breastfeeding
women since it might pass through breastfed milk. Consult your doctor before
taking the medicine.

Useful Diagnostic Tests

• Endoscopy
• Manometry