I UP Injection 5ml

Introduction About I UP INJECTION

I UP INJECTION contains Elemental Iron, which belongs to the group of medicines
called Iron replacement medicines. It is used to manage iron deficiency anaemia
(IDA) in adults and in children (above 14 years of age).

Your doctor may advise you to take relevant tests to understand your existing
condition. Before receiving I UP INJECTION inform your doctor if you are
pregnant, planning to get pregnant, or breast-feeding women. I UP INJECTION is
not recommended for use in children and adolescents (under 14 years of age), and
it should be used with caution in elderly patients (aged 65 years or older).
Consult your doctor before receiving the I UP INJECTION.

The most common side effects of receiving I UP INJECTION may cause headache,
dizziness, flushing, high blood pressure, nausea, and injection or infusion site
reactions. Consult your physician if any of the above side effects worsen.

Uses Of I UP INJECTION

• Used to manage iron deficiency anaemia

How I UP INJECTION Works

I UP INJECTION contains iron (III) hydroxide complexed with a carbohydrate
polymer called carboxymaltose, which is capable of releasing iron. The iron
released from the complex helps in the synthesis of haemoglobin and increases
the red blood cell count. As a result, it manages iron-deficiency anaemia.

How to use I UP INJECTION

I UP INJECTION will be administered to you only by a doctor or a nurse into a
vein as an intravenous injection or infusion. Your physician will decide the
correct dose and duration for you depending on your age, body weight, and
severity of the condition.

Side Effects Of I UP INJECTION

Common

• headache
• dizziness
• flushing
• high blood pressure
• nausea
• injection/infusion site reactions
• low levels of phosphorous in the blood

Uncommon

• numbness, prickling or tingling sensation of the skin
• change in taste sensation
• difficulty breathing
• indigestion
• constipation
• diarrhoea
• skin rash
• muscle or joint pain, back pain, pain in the arms or the legs
• swelling of the hands and feet, and chills

Rare

• inflammation of the vein
• flatulence

Contact your doctor immediately if you experience any of the following side
effects:

• Symptoms of a serious allergic reaction or Kounis syndrome (such as rashes, itching, swelling of the face, lips, mouth, tongue, throat, or body, causing difficulty breathing or wheezing, and chest pain)
• Severe or life-threatening allergic reactions are called anaphylactic reactions, which can be associated with heart problems, circulation problems (low blood pressure), and loss of consciousness
• Signs of a decrease in blood phosphorus causing softening of bones (osteomalacia) symptoms include worsening of tiredness, muscle or bone pain (pain in arms or legs, joints, or back), and may lead to fractures
• Signs of high blood pressure (such as facial flushing, dizziness, or nausea)
• Skin irritation and brownish discolouration of the skin at the injected site

How To Manage Side Effects

!### Constipation

Include fiber-rich foods in your diet, such as fresh fruits, vegetables, and
whole grain cereals, and drink plenty of fluids. Consult your doctor if the
symptom does not improve.

!### Diarrhea

Drink a lot of fluids, such as water or fruit juices, to keep yourself hydrated.
Avoid eating high-fat or spicy foods. If the symptom does not improve, consult
your doctor.

Headache

Take a rest and relax. Drink plenty of fluids, such as water. Apply a
pain-relieving balm to the forehead if necessary. Consult your doctor if your
headache does not improve.

!### Nausea And Vomiting

Stick to simple meals. Avoid eating oily, fried, or spicy foods. Do not lie down
or go to sleep immediately after eating. Consult your doctor if the symptom does
not improve.

!### Stomach Pain

Try to take a rest and relax. Eat and drink slowly or try to have smaller and
more frequent meals. Keep a heat pad on your stomach. If the symptom does not
improve, consult your doctor.

Warning & Precautions

!### Pregnancy

Monitoring requiredI UP INJECTION should be used with caution in pregnant women only if considered
clearly necessary. Inform your doctor if you are pregnant, think you may be
pregnant, or are planning to have a baby. Consult your doctor before receiving I
UP INJECTION.

!### Breastfeeding

Consult your doctorIf you are breastfeeding, consult your doctor for advice before receiving an I
UP INJECTION. It is unlikely that an I UP INJECTION represents a risk to a
breast-fed child.

!### Driving and Using Machines

Use with CautionI UP INJECTION is unlikely to impair the ability to drive or operate machines.

!### Kidney

Use with CautionI UP INJECTION should be used with caution in patients with chronic kidney
disease who are dependent on haemodialysis management. Consult your doctor
before receiving I UP INJECTION.

!### Liver

Use with CautionI UP INJECTION should be used with caution in patients with liver disease.
Before receiving I UP INJECTION, consult with your doctor.

!### Allergy

ContraindicatedDo not receive I UP INJECTION if you are allergic to Elemental Iron or any of
the other ingredients of this medicine or if you have experienced serious
allergic reactions to other injectable iron preparations.

!### Lungs

Use with CautionI UP INJECTION should be used with caution in patients with severe asthma.
Consult your doctor before receiving the I UP INJECTION.

!### Use In Pediatrics

ContraindicatedI UP INJECTION is not recommended for use in children (under 14 years of age).
Consult the child's doctor for advice on how to manage the condition.

!### Use In Geriatrics

Use with CautionI UP INJECTION should be used with caution in elderly patients (aged 65 years or
older). Consult your doctor before receiving the I UP INJECTION.

Others

I UP INJECTION is not recommended for use if you have:

• anaemia not caused by iron deficiency
• iron overload (too much iron in your body) or disturbances in the utilization of iron

Before receiving I UP INJECTION inform your doctor if you have:

• systemic lupus erythematosus
• rheumatoid arthritis
• eczema or other allergies
• an infection
• low levels of phosphate in the blood
• high blood pressure

Interactions

A. Drug-Drug interactions:

Before receiving I UP INJECTION, inform your doctor if you are using or have
recently taken any other medicines, including prescri
medicines, vitamins, or herbal supplements.

• Oral iron preparations such as ferrous ascorbate, ferrous sulphate, and ferric citrate (used to manage low levels of iron in the body)

Overdosage:

I UP INJECTION will be administered to you only by a doctor or a nurse in a
hospital, and so it is unlikely to receive an overdose. However, consult your
doctor or nurse if you experience any unusual symptoms.

Synopsis

Drug	:	Elemental Iron
Pharmacological Category	:	Iron replacement medicines
Therapeutic Indication	:	Iron Deficiency Anemia (IDA)
Dosage Forms	:	Injection

More Information

Storage

• Keep I UP INJECTION out of reach of children
• Store at room temperature

FAQs About I UP INJECTION

Q: What is the use of I UP INJECTION?

A: I UP INJECTION is used in the management of iron deficiency anaemia. Consult
your doctor before receiving the medicine.

Q: How does I UP INJECTION work?

A: I UP INJECTION contains iron (III) hydroxide complexed with a carbohydrate
polymer called carboxymaltose, which is capable of releasing iron. The iron
released from the complex helps in the synthesis of haemoglobin and increases
the red blood cell count. As a result, it manages iron-deficiency anaemia.

Q: Is I UP INJECTION safe to use in patients with kidney problems?

A: I UP INJECTION should be used with caution in patients with chronic kidney
disease who are dependent on haemodialysis management. Consult your doctor
before receiving I UP INJECTION.

Q: Who should avoid taking I UP INJECTION?

A: I UP INJECTION is not recommended for use in patients with evidence of iron
overload or disturbances in the utilization of iron, anaemia not caused by iron
deficiency, known allergies to Elemental Iron, or serious allergies to other
parenteral iron products.

Q: Is I UP INJECTION safe to use with elderly patients?

A: I UP INJECTION should be used with caution in elderly patients (aged 65 years
or older). Your doctor may monitor you carefully during administration and at a
certain time after administration of I UP INJECTION. Consult your doctor before
receiving the medicine.

Q: Can I UP INJECTION be used during pregnancy?

A: [GNKEYWORD] should be used with caution in pregnant women only if clearly
advised by your doctor. Inform your doctor if you are pregnant, think you may be
pregnant, or are planning to have a baby. Consult your doctor before receiving I
UP INJECTION.

Q: Can I UP INJECTION interact with other medications?

A: Yes, I UP INJECTION can interact with other medications, including certain
antibiotics, antifungals, antidepressants, and medications that affect heart
rhythm. It's crucial to inform your healthcare provider about all medications,
supplements, and herbal products you are taking before starting I UP INJECTION
therapy to avoid potential interactions.

Q: How often do I need to take I UP INJECTION?

A: The frequency of I UP INJECTION will depend on your specific condition and
management plan. Your healthcare provider will determine the appropriate dosing
schedule for your condition.

Q: What should I do if I miss a dose of I UP INJECTION?

A: It's crucial to follow your healthcare provider's instructions regarding
management. If you miss a dose, contact your healthcare provider for guidance.

Q: What are the side effects of receiving I UP INJECTION?

A: The most common side effects of receiving I UP INJECTION includes headache,
dizziness, flushing, high blood pressure, and nausea. Consult your physician if
any of the side effects worsen.

Q: What precautions must be taken while receiving I UP INJECTION?

A: Before receiving I UP INJECTION, inform your doctor if you have liver, kidney
disease, severe asthma, systemic lupus erythematosus, rheumatoid arthritis,
eczema or other allergies, infections, low levels of phosphate in the blood, or
high blood pressure.

Q: If a higher dose of I UP INJECTION is administered, will I get faster results?

A: No. Do not receive more than the recommended dose of I UP INJECTION, as it
may increase the risk of unwanted side effects. Your doctor will decide the
correct dose and duration depending on age, body weight, and disease conditions.

Useful Diagnostic Tests

• Complete Blood Count (CBC)/ Hemogram
• Ferritin /Iron Serum
• Iron Studies
• Iron Deficiency Profile
• Iron
• Total Iron Binding Capacity- TIBC
• Unsaturated Iron Binding Capacity (UIBC)
• Ferritin
• Anemia Basic Panel (Nutritional)
• Iron Deficiency Panel
• Iron Studies With Ferritin