Fulsed Injection 1ml

Introduction About FULSED INJECTION

FULSED INJECTION contains Midazolam, which belongs to the group of medicines
called central nervous system (CNS) depressants. It is used as a general
anaesthetic (medications that put you in a sleep-like state before surgery) in
adults.

It is also used in children and adults as preoperative sedation or conscious
sedation (depressed level of consciousness during which a patient retains
control over his protective reflexes and can respond) before the short
diagnostic or endoscopic procedure and for induction of general anaesthesia
before administration of another anaesthetic agent.

Avoid consuming alcohol while receiving FULSED INJECTION. Do not receive FULSED
INJECTION if you have breathing difficulties. Before receiving FULSED INJECTION,
inform your doctor if you have kidney problems, heart diseases, liver problems,
a history of drug abuse, sleep apnoea syndrome and myasthenia gravis.

FULSED INJECTION is generally not recommended for use in pregnant and
breastfeeding women unless considered clearly necessary. It should be used with
caution in elderly patients. FULSED INJECTION cause common side effects such as
hiccups, cough, nausea and vomiting. If any of these symptoms worsen, contact
your doctor for advice.

Uses Of FULSED INJECTION

• It is used as a general anaesthetic in adults
• It is also used as preoperative sedation or conscious sedation before the short diagnostic or endoscopic procedures and for induction of general anaesthesia before administration of another anaesthetic agent in children and adults

How FULSED INJECTION Works

FULSED INJECTION works by acting on certain receptors in the brain called GABA
receptors, which cause the release of a neurotransmitter called GABA that
transmits messages between the nerve cells. Hence, FULSED INJECTION helps
stabilize the altered electrical activity of nerve cells in the brain to induce
complete loss of consciousness and for sedation before the surgical or
diagnostic procedure.

How to use FULSED INJECTION

FULSED INJECTION will be given to you only by a doctor or a nurse into a vein as
an intravenous infusion. Your doctor will decide the correct dose and duration
for you depending on your age, body weight and disease condition.

Side Effects Of FULSED INJECTION

Common

• tenderness, redness and induration at the site of injection
• pain during injection
• hiccups
• cough
• nausea and vomiting

Uncommon

• inflammation of a vein causing pain and swelling at the injection site
• headache
• feeling drowsy
• low blood pressure
• exaggeration of existing diseases
• seizures

Rare

• taste changes and excessive salivation
• behavioural changes such as confusion, excitement, restlessness, agitation, irritability, anger, nightmares, hallucinations or psychosis
• temporary memory loss
• difficulty co-ordinating muscles
• seeing double images
• sleep disturbances and nightmare
• slurred speech,
• blocking of ears
• loss of balance and light-headedness

Stop receiving FULSED INJECTION and contact your doctor immediately if you
experience any of the following side effects:

• signs of a severe allergic reaction (sudden rash, itching or lumpy rash and swelling of the face, lips, tongue or other parts of the body along with shortness of breath, wheezing or trouble breathing)
• signs of a heart attack such as chest pain
• breathing problems, sometimes causing the breathing to stop
• muscle spasm around the voice box, causing choking

How To Manage Side Effects

Nausea and vomiting:

Take a rest to relax. Eat and drink slowly or try to have smaller and more
frequent meals. If the symptom does not improve, contact your doctor.

Cough:

Gargle with salt water and drink herbal teas made of ginger, turmeric and black
pepper. Consume only hot water. If the symptom does not improve, contact your
doctor.

Stomach upset:

Drink lots of fluids and water to keep yourself hydrated. Try to avoid taking
any medicine on your own to manage diarrhoea and consult your doctor if the
symptom gets worse.

Headache:

Try a cold pack or use a heating pad or hot compress. Ease pressure on your
scalp or head. Dim the lights. Hydrate yourself and practice relaxation. If
there is no improvement in symptoms, consult your doctor.

Warning & Precautions

!### Pregnancy

FULSED INJECTION is generally not recommended for use in pregnant women unless
considered clearly necessary. Consult your doctor before receiving the medicine.

!### Breastfeeding

FULSED INJECTION should be used with caution in breastfeeding women as it may
pass through the breast milk. Do not breastfeed for 24 hours after receiving
FULSED INJECTION. Consult your doctor receiving receiving the medicine.

!### Driving and Using Machines

Do not drive or operate any machines if you feel dizzy, sleepy forgetful or
impaired concentration and coordination after receiving FULSED INJECTION.

!### Alcohol

Avoid consum
you feel very sleepy and cause breathing problems.

!### Kidney

FULSED INJECTION should be used with caution in patients with kidney problems.
Consult your doctor before receiving FULSED INJECTION.

!### Liver

FULSED INJECTION should be used with caution in patients with liver problems.
Consult your doctor before receiving FULSED INJECTION.

!### Allergy

Do not receive FULSED INJECTION if you are allergic to midazolam or other
benzodiazepine medicines, such as diazepam or nitrazepam.

!### Lungs

FULSED INJECTION is not recommended for use in patients with severe breathing
problems. Consult your doctor before receiving FULSED INJECTION.

!### Heart Disease

FULSED INJECTION should be used with caution in patients with heart problems.
Consult your doctor before receiving FULSED INJECTION.

Others

Before receiving FULSED INJECTION, inform your doctor if you:

• have an illness that makes you feel very weak, run down and short of energy
• have myasthenia gravis
• have sleep apnoea syndrome
• have ever had alcohol or drug problems

Use in paediatrics:

FULSED INJECTION should be cautious in infants, children and adolescents (less
than 6 months to 16 years of age). Consult your doctor before receiving the
medicine.

Use in geriatrics:

FULSED INJECTION should be used with caution in elderly (60 years and above)
patients because there is an increased risk of fall, fractures and
life-threatening side effects. Consult your doctor for advice before receiving
the medicine.

Interactions

A. Drug-Drug interactions:

Before receiving FULSED INJECTION, inform your doctor if you are taking any of
the following medicine:

• medicines used for managing depression (Ex. citalopram, sertraline, fluoxetine, escitalopram)
• medicines that help to calm down and sleep (Ex. zopiclone, zolpidem, suvorexant, Flurazepam and triazolam)
• carbamazepine or phenytoin (these may be used for fits or seizures)
• medicines used to manage fungal infections (ex. ketoconazole, itraconazole, voriconazole)
• ritonavir, boceprevir and telaprevir (used to manage viral infections)
• medicines used to manage bacterial infections (Ex. clarithromycin, erythromycin, isoniazid)
• medicines used to lower blood pressure levels (Ex. verapamil, diltiazem)
• rifampicin (used to manage tuberculosis
• medicines to reduce pain (Ex. buprenorphine, methadone and fentanyl)
• Atorvastatin (used to manage high cholesterol)
• Medicines used for allergic reactions (Ex. brompheniramine, cetirizine, chlorpheniramine, diphenhydramine and fexofenadine)
• St John’s Wort (herbal medicine for managing depression)

Overdosage:

FULSED INJECTION will be administered to you only by a doctor or a nurse in a
hospital, so it is unlikely to receive an overdose. However, consult your doctor
or nurse if you experience any unusual symptoms.

Synopsis

Drug	:	Midazolam
Pharmacological Category	:	Benzodiazepines
Therapeutic Indication	:	General anaesthesia, conscious sedation
Dosage Forms	:	Tablet, nasal spray, injection, syrup

More Information

• Keep FULSED INJECTION out of reach from children
• Store at room temperature

FAQs About FULSED INJECTION

What is FULSED INJECTION used for?

FULSED INJECTION is used as a general anaesthetic in adults and also used as
preoperative sedation or conscious sedation before the short diagnostic or
endoscopic procedures and for induction of general anaesthesia before
administration of another anaesthetic agent in children and adults.

What kind of drug is FULSED INJECTION?

FULSED INJECTION belongs to a class of medications called benzodiazepines that
works by slowing activity in the brain to allow relaxation and sleep. Hence,
FULSED INJECTION is used before medical procedures or anaesthesia for surgery to
cause drowsiness, relieve anxiety and manage any memory of the event.

Can we suddenly stop receiving FULSED INJECTION?

No, FULSED INJECTION can cause withdrawal symptoms such as headaches, diarrhoea,
muscle pain, extreme anxiety, tension, restlessness, confusion and irritability
on the sudden discontinuation of the medicine. Therefore, always consult your
doctor before stopping the medicine.

Does FULSED INJECTION cause any side effects while receiving?

FULSED INJECTION can cause side effects such as hiccups, cough, nausea,
vomiting, depression, tiredness, dizziness, temporary memory loss and headache.
If any of these symptoms get worsen, contact your doctor immediately for advice.

Can we use FULSED INJECTION for pregnant women?

FULSED INJECTION is generally not recommended for use in pregnant women unless
considered necessary as it might increase the risk of congenital malformations
in neonates. If you are pregnant or think you may be pregnant or are planning to
have a baby, ask your doctor for advice before receiving FULSED INJECTION.