DOL Proxyvon 100mg Tablet 10'S

Introduction About DOL PROXYVON 100MG TABLET

DOL PROXYVON 100MG TABLET contains Tapentadol which belongs to the group of
medicines called Opioids. It is used in adults for the management of severe
chronic pain which can only be managed by a strong (opioid) painkiller.

DOL PROXYVON 100MG TABLET is not recommended for use in patients having severe
kidney or liver problems, asthma or if your breathing is dangerously slow or
shallow (respiratory depression, hypercapnia), paralysis of the gut (muscles of
the gastrointestinal tract).

DOL PROXYVON 100MG TABLET should be used with caution in patients who have slow
or shallow breathing, increased pressure in the brain, disturbed consciousness
up to coma, head injury or brain tumour, pancreatic or biliary tract disease
(pancreatitis), increased tendency towards epilepsy, have tendency to abuse
medicines (habituating), moderate liver problems, kidney disease and intolerance
to certain sugars (such as lactose).

DOL PROXYVON 100MG TABLET is not recommended for use in pregnant women unless
recommended by the doctor and it is not recommended for use in breast-feeding
women. DOL PROXYVON 100MG TABLET is not recommended for use in children and
adolescents (below 18 years of age) and it should be used with caution in
elderly patients (aged 65 years of age).

The most common side effects of taking DOL PROXYVON 100MG TABLET are nausea,
constipation, dizziness, drowsiness, headache, decreased appetite, indigestion
and flushing. Consult your doctor if any of the side effects worsen.

Uses Of DOL PROXYVON 100MG TABLET

• manages severe chronic pain in adults

How DOL PROXYVON 100MG TABLET Works

DOL PROXYVON 100MG TABLET acts directly on the central nervous system and
reduces the feeling of pain by interru
between brain and the body. DOL PROXYVON 100MG TABLET binds with certain
receptors called µ-opioid receptors and also increases the release of a nerve
chemical called norepinephrine which causes inhibition of certain receptors
leading to pain relief.

How to use DOL PROXYVON 100MG TABLET

Take DOL PROXYVON 100MG TABLET as advised by your doctor. Swallow the medicine
with a glass of water. Do not crush or chew the medicine. Your doctor will
decide the correct dose and duration for you depending upon your age, body
weight and disease condition.

Side Effects Of DOL PROXYVON 100MG TABLET

Common

• nausea, vomiting
• constipation, diarrhoea, indigestion
• dizziness, drowsiness, headache
• decreased appetite
• anxiety, depressed mood
• sleep problem
• nervousness, restlessness
• disturbance in attention
• trembling, muscle twitches
• flushing
• shortness of breath
• itching, rash
• increased sweating
• feeling of weakness, fatigue
• feeling of body temperature change
• mucosal dryness
• accumulation of water in the tissue

Uncommon

• allergic reaction including swelling beneath the skin, hives, and in severe cases difficulty breathing, collapse or shock, a fall in blood pressure
• weight loss
• disorientation, confusion
• excitability (agitation)
• perce
• abnormal dreams
• euphoric mood (extreme happiness and excitement)
• depressed level of consciousness
• memory or mental impairment
• fainting
• sedation (excessive sleepiness)
• balance disorder
• difficulty in speaking
• numbness, abnormal sensations of the skin such as tingling, prickling
• abnormal vision
• faster or slower heart rate, palpitations, decreased blood pressure
• abdominal discomfort
• hives
• delay in passing urine or frequent urination
• sexual dysfunction
• drug withdrawal syndrome
• feeling abnormal, irritability

Rare

• drug dependence
• thinking abnormal
• epile
• near fainting
• abnormal coordination
• dangerously slow or shallow breathing (respiratory depression)
• impaired gastric emptying
• feeling drunk
• feeling of relaxation

Stop taking DOL PROXYVON 100MG TABLET and inform your doctor immediately if you
experience any of the following side effects:

• signs of an allergic reaction (such as difficulties in breathing, wheezing, swelling of the eyelids, face or lips, rash or itching (covering your whole body)
• breathing more slowly or weakly than normal

How To Manage Side Effects

Nausea or vomiting:

Stick to simple meals while taking this medicine. Avoid eating oily rich, fried
or spicy foods. Do not lie down or sleep immediately after eating. Consult your
doctor if the symptom does not improve.

Constipation:

Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and
drink plenty of water. Exercise more regularly (such as daily walk). Consult
your doctor if the symptom does not improve.

Diarrhoea:

Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating
high-fat or spicy foods. Try to avoid taking any medicine on your own to manage
diarrhea and consult your doctor if the symptom gets worse.

Stomach pain:

Try to rest and relax. Eat and drink slowly or try to have smaller meals more
frequently. Keep a heat pad on your stomach. If the symptom does not improve,
consult your doctor.

Headache:

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to
be relaxed and stress free. Apply pain relieving balm on your forehead if
necessary. Consult your doctor if the symptom does not improve.

Warning & Precautions

!### Pregnancy

DOL PROXYVON 100MG TABLET is not recommended for use in pregnant women unless
recommended by the doctor as it can cause withdrawal symptoms in the new-born
baby when used for prolonged period of time, which might be life threatening and
could also possibly lead to dangerously slow or shallow breathing in the
newborn. Consult with your doctor before taking DOL PROXYVON 100MG TABLET.

!### Breastfeeding

DOL PROXYVON 100MG TABLET is not recommended for use in breastfeeding women as
it may pass through the breast milk. Consult your doctor before taking DOL
PROXYVON 100MG TABLET.

!### Driving and Using Machines

Do not drive or use any machinery while taking DOL PROXYVON 100MG TABLET if you
experience drowsiness, dizziness, blurred vision or impairment of reactions.

!### Alcohol

Avoid consum
increase the effect of drowsiness.

!### Kidney

DOL PROXYVON 100MG TABLET is not recommended for use in patients with severe
kidney problems. It should be used with caution in patients suffering from
kidney disease. Consult your doctor before taking DOL PROXYVON 100MG TABLET.

!### Liver

DOL PROXYVON 100MG TABLET is not recommended for use in patients with severe
liver problems. DOL PROXYVON 100MG TABLET should be used with caution in
patients with moderate liver problems and your doctor may adjust the dose.
Consult your doctor before taking DOL PROXYVON 100MG TABLET.

Allergy

Do not take DOL PROXYVON 100MG TABLET if you are allergic to Tapentadol or any
other ingredients of this medicine.

!### Lungs

DOL PROXYVON 100MG TABLET is not recommended for use in patients having lung
diseases such as asthma or dangerously slow and shallow breathing (hypercapnia,
respiratory depression). It should be used with caution in patients having other
breathing issues (slow or shallow breathing). Consult your doctor before taking
DOL PROXYVON 100MG TABLET.

Others

DOL PROXYVON 100MG TABLET is not recommended for use if you:

• have paralysis of the gut (muscles of the gastrointestinal tract)
• have acute poisoning of alcohol, sleeping pills, pain relievers or other psychotropic medicines (medicines that affect mood and emotions)

Before taking DOL PROXYVON 100MG TABLET inform your doctor if you:

• have increased pressure in the brain or disturbed consciousness up to coma
• had a head injury or brain tumour
• have a disease affecting the pancreas (such as pancreatitis) or biliary tract
• have tendency towards fits
• have tendency to abuse medicines (getting habitual of it)
• have lactose intolerance

Use in paediatrics:

DOL PROXYVON 100MG TABLET is not recommended for use in children and adolescents
(below 18 years of age). Consult your child’s doctor for advice.

Use in geriatrics:

DOL PROXYVON 100MG TABLET should be used with caution in elderly patients (aged
65 years and above) due to delayed excretion of this medicine in this age group
and your doctor may adjust the dose. Consult your doctor before taking DOL
PROXYVON 100MG TABLET.

Interactions

A. Drug–Drug Interactions:

Before taking DOL PROXYVON 100MG TABLET inform your doctor if you are taking any
of the following medicines:

• sedatives such as zolpidem, barbiturates (Ex. amobarbital, pentobarbital) antidepressants such as paroxetine, sertraline and anti-psychotics such as loxapine, clozapine, monoamine oxidase inhibitors (MAOIs) such as isocarboxazid (used to manage depression, anxiety, mood disorders, sleep disturbances)
• opioids such as codeine, oxymorphone, mixed mu-opioid agonist/antagonists such as pentazocine, nalbuphine, partial mu-opioid agonists such as buprenorphine (used to manage severe pain)
• antihistamines such as cetirizine, loratadine (used to manage allergy)
• rifampicin (used to manage tuberculosis)
• St. john’s wort (herbal medicine used to manage depression)

Overdosage:

If you or anyone else accidentally takes too much of DOL PROXYVON 100MG TABLET,
consult your doctor immediately or visit the nearby hospital. Overdosage
symptoms of DOL PROXYVON 100MG TABLET are pin-point pupils, vomiting, fast
heartbeat, drop in blood pressure, collapse, disturbed consciousness or coma
(deep unconsciousness), epile
shallow breathing or stopping breathing may occur.

Synopsis

Drug	:	Tapentadol
Pharmacological Category	:	mu-opioid agonists
Therapeutic Indication	:	Severe chronic pain
Dosage Forms	:	Tablet, Nasal Spray, Capsule

More Information

• Keep DOL PROXYVON 100MG TABLET out of reach of children
• Store at room temperature below 25°C

FAQs About DOL PROXYVON 100MG TABLET

What is DOL PROXYVON 100MG TABLET and why is it prescribed?

DOL PROXYVON 100MG TABLET contains Tapentadol which belongs to the group of
medicines called Opioids. It is used in the management of severe chronic pain in
adults which can only be managed by a strong (opioid) painkiller.

Is DOL PROXYVON 100MG TABLET a habit-forming medicine?

DOL PROXYVON 100MG TABLET may cause psychological and physical addiction. If you
have a tendency to become habitual to medicines or if you are dependent on
medicines, you should only take DOL PROXYVON 100MG TABLET for short periods. You
must consult with your doctor priorly and discuss with them.

Can DOL PROXYVON 100MG TABLET cause sleep related breathing problems?

DOL PROXYVON 100MG TABLET contains an active substance that belongs to the group
of opioids which can cause sleep related breathing disorders. This includes
central sleep apnoea (shallow, pause of breathing during sleep) and
sleep-related hypoxemia (lowered levels of oxygen in the blood). The risk of
experiencing such problems depends upon the dose of DOL PROXYVON 100MG TABLET.
Hence, you should not exceed the daily recommended dose. Your doctor may
consider altering your dosage if you experience any such problems.

Can I stop taking DOL PROXYVON 100MG TABLET on my own if I start to feel
better?

You must not stop taking DOL PROXYVON 100MG TABLET until and unless your doctor
asks you to stop. Stopping suddenly or too soon may cause your pain to return.
If you have been taking DOL PROXYVON 100MG TABLET for quite some time and you
stop suddenly, you may experience symptoms such as restlessness, runny nose,
yawning, watery eyes, sweating, chills, muscle pain, joint pain, dilated pupils,
irritability, anxiety, backache, weakness, abdominal cramps, etc. If you feel
any such symptoms or at all you wish to discontinue taking DOL PROXYVON 100MG
TABLET, ask for your doctor’s advice.

Does DOL PROXYVON 100MG TABLET affect my ability to drive?

Do not drive or use any machinery if you feel drowsy, dizzy, blurring of vision
or impairment of concentration after taking DOL PROXYVON 100MG TABLET. You can
resume with your activities once you feel normal again. Consult your doctor for
advice.