DEXIMON PX Eye/Ear Drops 5ml

Introduction About DEXIMON PX EYE/EAR DROPS

DEXIMON PX EYE/EAR DROPS is a combination of Chloramphenicol and Polymyxin B
which belongs to the group of medicines called Antibiotics and Corticosteroids
respectively. It is used in adults to manage bacterial infections of the eyes
and ear canal. Eye infection is characterized by warmth, redness, swelling and
pain. Ear infection can show symptoms like ear pain, fever, irritability,
rubbing or tugging ear or difficulty sleeping.

During course of the management your doctor might regularly examine your eye and
ear to avoid any untoward side effects. The safety and effectiveness of DEXIMON
PX EYE/EAR DROPS have not been established in children.

Before using DEXIMON PX EYE/EAR DROPS, inform your doctor if you have an injury
or ulcer of the cornea, fungal or viral (herpes simplex) eye infections, severe
blood disorders, liver problems or family history of impaired bone marrow
function. DEXIMON PX EYE/EAR DROPS is not recommended in pregnant or
breastfeeding women.

The most common side effects of using DEXIMON PX EYE/EAR DROPS are temporary
burning, stinging, irritation, itching and redness. Consult your doctor if any
of the side effects worsen.

Uses Of DEXIMON PX EYE/EAR DROPS

• Manage bacterial infections of the eyes and ear canal

How DEXIMON PX EYE/EAR DROPS Works

DEXIMON PX EYE/EAR DROPS manages infection, where chloramphenicol inhibits
bacterial protein synthesis by binding to the 50S ribosomal subunit and directly
managing the formation of bacterial protein, dexamethasone suppresses the
migration and decreases the multiplication of certain cells that are responsible
for inflammation, along with making the membrane less permeable and polymyxin B
interacts with certain molecules of the outer membrane of infecting bacteria,
changing membrane permeability and killing the cell.

How to use DEXIMON PX EYE/EAR DROPS

Use DEXIMON PX EYE/EAR DROPS as advised by your doctor. It is for external use
only. Do not touch the tip of the dropper on any surface. Squeeze the dropper
gently, then dispense the medication inside the lower eyelid or ear. Your doctor
will decide the correct dose and duration for you depending upon your age,
disease condition and body weight.

Side Effects Of DEXIMON PX EYE/EAR DROPS

Common

• temporary burning, stinging, irritation, itching, redness

Stop using DEXIMON PX EYE/EAR DROPS and consult your doctor immediately if you
experience any of the following side effects:

• blurry eyesight or other visual disturbances
• cushing's syndrome or adrenal suppression

How To Manage Side Effects

!### Eye irritation Or Itching

Wash your eyes with plain cold water. Place an ice pack on your eye to soothe
the irritation. Avoid straining your eyes by keeping away from mobile phones,
laptops or television. Wear protective sunglasses while going outdoors. Consult
your doctor if the symptom does not improve.

Warning & Precautions

!### Pregnancy

ContraindicatedDEXIMON PX EYE/EAR DROPS is not recommended for use in pregnant women. Consult
your doctor before using it.

!### Breastfeeding

ContraindicatedDEXIMON PX EYE/EAR DROPS is not recommended for use in breastfeeding women.
Consult your doctor before using it.

!### Driving and Using Machines

Use with CautionDo not drive or operate machinery if you are not sure if you have complete
mental and physical alertness after using DEXIMON PX EYE/EAR DROPS.

!### Kidney

Use with CautionDEXIMON PX EYE/EAR DROPS should be used with caution in patients with kidney
failure. Consult your doctor before using it.

!### Liver

Use with CautionDEXIMON PX EYE/EAR DROPS should be used with caution in patients with liver
impairment. Consult your doctor before using it.

!### Allergy

ContraindicatedDo not use DEXIMON PX EYE/EAR DROPS if you are allergic to Chloramphenicol,
Dexamethasone, Polymyxin B or any other ingredients of this medicine.

!### Use In Pediatrics

Consult your doctorThe safety and effectiveness of DEXIMON PX EYE/EAR DROPS have not been
established in children. Consult your doctor before using it.

!### Use In Geriatrics

Consult your doctorThe safety and effectiveness of DEXIMON PX EYE/EAR DROPS have not been
established in elderly patients. Consult your doctor before using it.

Others

DEXIMON PX EYE/EAR DROPS is not recommended for use if you:

• had experienced bone marrow suppression during previous exposure to chloramphenicol
• have known personal or family history of blood dyscrasias including aplastic anaemia
• have fungal eye infection
• inflammation of front layer of due to herpes simplex virus
• infection of parts of eye like vaccinia, varicella and other viral infection

Before using DEXIMON PX EYE/EAR DROPS, inform your doctor if you:

• have diseases that cause corneal thinning
• have severe bacterial conjunctivitis or an infection which is not confined to the conjunctivae
• wear contact lenses
• have diabetes (high blood sugar)
• you have any fungal infection

Interactions

A. Drug-Drug interactions:

Before using DEXIMON PX EYE/EAR DROPS, inform your doctor if you are using any
of the following medicines:

• atropine and related compounds (used to manage slow heartbeat)
• medicines used to manage fits (Ex. phenytoin, phenobarbitone)
• ephedrine (used to manage breathing problems)
• rifampicin (used to manage bacterial infections)
• neomycin (used to manage eye infections)
• medicines used to manage HIV infection (Ex. ritonavir, cobicistat)
• medicines used on skin to reduce pain (Ex. diclofenac, ibuprofen)
• medicines used on skin to reduce inflammation (Ex. hydrocortisone, mometasone)

Overdosage:

If you or anyone else accidentally used too much of DEXIMON PX EYE/EAR DROPS,
consult your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Chloramphenicol, Polymyxin B, Dexamethasone
Pharmacological Category	:	Antibiotics, Corticosteroid
Therapeutic Indication	:	Bacterial infection of eye or ear canal
Dosage Forms	:	Eye/Ear drops, Eye/Ear ointment

More Information

Storage

• Keep DEXIMON PX EYE/EAR DROPS out of reach of children
• Store in a cool place

FAQs About DEXIMON PX EYE/EAR DROPS

Q: Can DEXIMON PX EYE/EAR DROPS be used for fungal infections?

A: No, DEXIMON PX EYE/EAR DROPS is used in patients with bacterial infections.
Do not use this medicine for any other indication than prescribed for. Consult
your doctor before using it for other purposes.

Q: Can I wear contact lenses while using DEXIMON PX EYE/EAR DROPS?

A: No, all types of contact lenses should be avoided when you are being managed
for eye infections. Call you doctor for further queries regarding DEXIMON PX
EYE/EAR DROPS use.

Q: Can I stop using DEXIMON PX EYE/EAR DROPS on my own?

A: Do not stop using DEXIMON PX EYE/EAR DROPS unless your doctor advises you to
do so. You might need to discontinue using it in case any new infections or
serious side effects occur. Call you doctor for further queries regarding
DEXIMON PX EYE/EAR DROPS use.

Q: Can DEXIMON PX EYE/EAR DROPS be used in children?

A: The safety and effectiveness of DEXIMON PX EYE/EAR DROPS is not established
in children. Your child’s doctor will select a suitable alternative management
for your child to manage the infection.

Q: What if I forget to use a dose of DEXIMON PX EYE/EAR DROPS?

A: If you forget to use a dose of DEXIMON PX EYE/EAR DROPS, use it as soon as
you remember. However, omit the missed dose if it is almost time for the next
one. Do not use the medicine two times to make up for a forgotten dose.

Q: What precautions do I need to follow while taking DEXIMON PX EYE/EAR DROPS?

A: Patients using DEXIMON PX EYE/EAR DROPS must inform their doctor about their
pre-existing disease conditions like injury or ulcer of the cornea, fungal or
viral (herpes simplex) eye infections, severe blood disorders, liver problems or
family history of impaired bone marrow function. Patients should also inform if
they are pregnant, breast-feeding or having any allergies. Contact your doctor
immediately if you have any unusual symptoms.

Q: Can DEXIMON PX EYE/EAR DROPS be used during pregnancy?

A: DEXIMON PX EYE/EAR DROPS is not recommended for use during pregnancy as the
safety of one of its ingredients in pregnancy has not been established and it
may be absorbed in blood and cross the placenta. If you are pregnant, think you
may be pregnant or planning to get pregnant, consult your doctor before using
this medicine. Inform your doctor immediately if you become pregnant during
management with DEXIMON PX EYE/EAR DROPS.

Useful Diagnostic Tests

• Tympanometry