Debrilyse Tablet 10'S

Introduction About DEBRILYSE TABLET

DEBRILYSE TABLET is a combination of Bromelain, Rutoside, and Trypsin, which
belongs to the group of medicines called Proteolytic enzymes and Flavonoids,
respectively. It is used in the management of pain and inflammation associated
with osteoarthritis, rheumatoid arthritis, gout, joint issues related to
inflammation, pain and swelling of joints, swelling associated with surgical
wounds, pulmonary edema, ulcerative colitis, sports and accidental injuries,
muscular cramps and spasms, tendinitis, bursitis, dental extraction, sinusitis,
bronchitis, and rhinitis.

Prior to starting the management with DEBRILYSE TABLET, your doctor might want
you to take several diagnostic tests to understand your existing condition and
to safely use this medicine to manage the risk of any unusual effects.

DEBRILYSE TABLET is not recommended for use in patients with hemophilia (a
disorder in which blood doesn't clot normally), liver or kidney disorders, or
patients undergoing haemodialysis. DEBRILYSE TABLET should be taken with caution
in patients with any bleeding disorders and heart disease.

DEBRILYSE TABLET is not recommended for use in pregnant and breastfeeding women.
There is no data on the use of DEBRILYSE TABLET in children or elderly patients;
hence, always consult your doctor for advice before taking this medicine.

The most common side effects of taking DEBRILYSE TABLET are nausea, diarrhea,
stomach upset, tiredness, dry mouth, and skin rash. Consult your doctor if any
of the side effects worsen.

Uses Of DEBRILYSE TABLET

Used in the management of pain and inflammation associated with the following:

• Osteoarthritis, rheumatoid arthritis, gout
• Joint issues related to inflammation
• Pain and swelling of joints
• Swelling associated with surgical wounds
• Pulmonary edema
• Ulcerative colitis
• Sports and accidental injuries
• Muscular cramps and spasms
• Tendinitis and bursitis
• Dental extraction
• Sinusitis, bronchitis, and rhinitis

How DEBRILYSE TABLET Works

DEBRILYSE TABLET helps in managing pain and inflammation associated with various
conditions where bromelain and trypsin are protease enzymes that decrease
inflammation by inhibiting the substances that are responsible for it called
proinflammatory prostaglandins. It also influences blood clotting by increasing
the activity of a protein called fibrinogen. Rutoside is a flavonoid that works
by enhancing the strength of blood vessels and decreasing their ability to break
down.

How to use DEBRILYSE TABLET

Take DEBRILYSE TABLET as advised by your physician. Swallow the medicine with
enough water. Do not crush or chew the medicine. Your doctor will decide the
correct dose and duration of DEBRILYSE TABLET for you depending on your age,
body weight, and disease condition.

Side Effects Of DEBRILYSE TABLET

Common

• Stomach upset
• Diarrhoea
• Dizziness, headache
• Dry mouth
• Tiredness
• Nausea, indigestion
• Constipation
• Skin rash

Rare

• Allergic reactions

How To Manage Side Effects

!### Constipation

Take fiber-rich foods in your diet, such as fresh fruits, vegetables, and whole
grain cereals, and drink plenty of fluids. Exercise regularly (such as walking)
and stay active. Consult your doctor if the symptom does not improve.

!### Diarrhea

Drink a lot of fluids, such as water or fruit juices, to keep yourself hydrated.
Do not take any medicine on your own to manage diarrhea. Consult your doctor if
the symptom does not improve.

!### Dry Mouth

Sip water and other sugar-free liquids regularly. Do not use mouthwashes that
contain alcohol because they can make your mouth dry; use mouthwash that is used
only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco
products. Consult your doctor if the symptom does not improve.

Headache

Rest and relax. Drink plenty of fluids, such as water or electrolytes. Apply a
pain-relieving balm on the forehead if required. Do not consume too much
alcohol. Consult your doctor if the symptom does not improve.

!### Tiredness

Drink plenty of fluid, eat a balanced diet, and frequent meals. Do regular
minimal exercise and follow a regular sleep schedule. Consult your doctor if the
symptom does not improve.

Warning & Precautions

!### Pregnancy

ContraindicatedDEBRILYSE TABLET is not recommended for use in pregnant women. Consult your
doctor before taking DEBRILYSE TABLET.

!### Breastfeeding

ContraindicatedDEBRILYSE TABLET is not recommended for use in breastfeeding women. Consult your
doctor before taking DEBRILYSE TABLET.

!### Alcohol

ContraindicatedAvoid consum

!### Kidney

ContraindicatedDEBRILYSE TABLET is not recommended for use in patients with kidney disorders
and in patients undergoing haemodialysis. Consult your doctor before taking
DEBRILYSE TABLET.

!### Liver

ContraindicatedDEBRILYSE TABLET is not recommended for use in patients with liver disorders.
Consult your doctor before taking DEBRILYSE TABLET.

!### Allergy

ContraindicatedDo not take DEBRILYSE TABLET if you are allergic to Bromelain, Rutoside, and
Trypsin.

!### Heart Disease

Use with CautionDEBRILYSE TABLET should be used with caution in patients with heart disease.
Consult your doctor before taking it.

Others

DEBRILYSE TABLET is not recommended for use if you:

• Have hemophilia (a disorder in which blood doesn't clot normally)

Before taking DEBRILYSE TABLET, inform your doctor if you have:

• Any other bleeding disorder

Interactions

A. Drug-Drug Interactions:

Before taking DEBRILYSE TABLET, inform your doctor if you are taking any of the
following medicines:

• Digoxin (used to manage heart problems)
• Ramipril (used to manage high blood pressure)

Overdosage:

If you or anyone else accidentally take too much of DEBRILYSE TABLET, consult
your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Bromelain, Rutoside, Trypsin
Pharmacological Category	:	Proteases, Flavonoids, and Proteolytic enzymes
Therapeutic Indication	:	Pain and inflammation associated with various conditions
Dosage Forms	:	Tablet, Capsule

More Information

Storage

• Keep DEBRILYSE TABLET out of reach of children
• Store below 25°C

FAQs About DEBRILYSE TABLET

Q: Does DEBRILYSE TABLET cause stomach disturbances?

A: Yes, DEBRILYSE TABLET can cause side effects like vomiting, nausea, diarrhea,
indigestion, and stomach bloating. Do not take any medication on your own to
manage the specific symptom. Consult your doctor if any of the side effects
worsen or bother you.

Q: Can DEBRILYSE TABLET be used in patients with kidney problems?

A: DEBRILYSE TABLET is not recommended for use in patients with kidney disorders
and in patients undergoing haemodialysis. Consult your doctor before taking it.

Q: Is DEBRILYSE TABLET safe to use in pregnant women?

A: DEBRILYSE TABLET is not recommended for use in pregnant women. Consult your
doctor for advice before taking this medicine if you are pregnant or planning to
get pregnant.

Q: Is DEBRILYSE TABLET safe to use in patients with heart disease?

A: DEBRILYSE TABLET should be used with caution in patients with heart disease
because it may increase the risk of increased heart rate. Consult your doctor
for advice before taking this medicine.

Q: Can DEBRILYSE TABLET be given to children?

A: There is no information regarding the use of DEBRILYSE TABLET in children.
Your child’s doctor will select a suitable alternative therapy for your child to
manage the specific condition.

Q: What is DEBRILYSE TABLET used for?

A: DEBRILYSE TABLET is used in the management of pain and inflammation
associated with osteoarthritis, rheumatoid arthritis, gout, joint issues related
to inflammation, pain and swelling of joints, swelling associated with surgical
wounds, pulmonary edema, ulcerative colitis, sports and accidental injuries,
muscular cramps and spasms, tendinitis, bursitis, dental extraction, sinusitis,
bronchitis, and rhinitis.

Q: How does DEBRILYSE TABLET work?

A: DEBRILYSE TABLET helps in managing pain and inflammation associated with
various conditions where bromelain and trypsin are protease enzymes that
decrease inflammation by inhibiting the substances that are responsible for it
called proinflammatory prostaglandins. It also influences blood clotting by
increasing the activity of a protein called fibrinogen. Rutoside is a flavonoid
that works by enhancing the strength of blood vessels and decreasing their
ability to break down.

Q: What are the side effects of DEBRILYSE TABLET?

A: The most common side effects of taking DEBRILYSE TABLET are nausea, diarrhea,
stomach upset, tiredness, dry mouth, and skin rash. Consult your doctor if any
of the side effects worsen.

Q: How should I take DEBRILYSE TABLET?

A:Take DEBRILYSE TABLET as advised by your physician. Swallow the medicine with
enough water. Do not crush or chew the medicine. Your doctor will decide the
correct dose and duration of DEBRILYSE TABLET for you depending on your age,
body weight, and disease condition.

Q: Who should not take DEBRILYSE TABLET?

A:DEBRILYSE TABLET is not recommended for use in patients with hemophilia (a
disorder in which blood doesn't clot normally), kidney disorders, patients
undergoing haemodialysis, liver disorders, or if you are allergic to Bromelain,
Rutoside and Trypsin. Consult your doctor before taking DEBRILYSE TABLET.

Q: What precautions must be taken while using DEBRILYSE TABLET?

A: Before taking DEBRILYSE TABLET, inform your doctor if you have heart disease
or any other bleeding disorder.

Useful Diagnostic Tests

• Complete Blood Count (CBC)/ Hemogram
• Calcium
• Basic Arthritis Care
• Extended Arthritis Care
• Comprehensive Arthritis Care
• Frequent Pain Check Package
• Bone Strength Package
• Bone Profile – Advanced
• Autoimmune Arthritis Panel