Dalcinex Injection 2ml

Introduction About DALCINEX INJECTION

DALCINEX INJECTION contains Clindamycin, which belongs to the group of medicines
called Antibiotics. It is used to manage serious bacterial infections in adults
and adolescents above 12 years of age. Bacterial infection occurs when bacteria
enter the body, increasing in number and causing a reaction in the body.
Symptoms include fever, fatigue, headache, nausea, vomiting and swollen lymph
nodes in the neck, armpits, groin or elsewhere.

Before receiving DALCINEX INJECTION, inform your doctor if you have or ever had
impaired kidney and liver function, gastrointestinal diseases (colon
inflammation) or problems with muscle function (Parkinson’s disease, myasthenia
gravis). DALCINEX INJECTION should be used with caution in pregnant and
breastfeeding women, consult your doctor before receiving.

DALCINEX INJECTION is generally not recommended for use in children below 12
years of age. DALCINEX INJECTION should be used with caution in elderly patients
above 60 years of age. The most common side effects of receiving DALCINEX
INJECTION are nausea, abdominal pain, vomiting, diarrhea, blood abnormalities
and skin rashes. Consult your doctor if your symptoms do not improve.

Uses Of DALCINEX INJECTION

• Manage serious bacterial infections in adults and adolescents (over 12 years of age)

How DALCINEX INJECTION Works

DALCINEX INJECTION acts against the bacteria by binding to the 50S subunit of
the bacterial ribosome (site of protein synthesis). Which in turn manages
protein synthesis and kills the infection-causing bacteria.

How to use DALCINEX INJECTION

DALCINEX INJECTION will be administered to you only by a doctor or a nurse into
your vein (intravenous infusion with a drip). Your doctor will decide the
correct dose and duration for you depending on your age, body weight and disease
condition.

Side Effects Of DALCINEX INJECTION

Common

• Gastrointestinal disorders (nausea, abdominal pain, vomiting, diarrhea)
• Severe or prolonged or bloody diarrhea during or after management may be a sign of bowel inflammation (pseudomembranous colitis)
• Blood abnormalities (changes in the number of white blood cells or reduction in blood platelets (which increases the risk of bleeding or bruising))
• Diseases of the blood vessels such as inflammation of the veins(thrombophlebitis).
• Skin lesions with large blistering skin rash (maculopapular exanthema, morbilliform exanthema), ’nettle rash’ (urticaria)
• The results of liver tests may be affected

Uncommon

• Nervous system disturbances, such as an inhibiting nerve impulse progression (neuromuscular blocking effect) and altered taste (dysgeusia)
• Difficulty breathing, low blood pressure
• Pain and abscess at the site of injection

Rare

• Fever
• Itchy skin (pruritus).
• Inflammation of the vaginal mucosa (vaginitis)
• Serious skin reactions:
• Stevens-Johnson syndrome (peeling of large areas of skin, especially around the mouth, nose, eyes, and genitals) and Lyell syndrome (a more serious illness with blistering of the skin)
• Extensive red skin rash with skin flaking (exfoliative dermatitis, bullous dermatitis, erythema multiforme)
• Serious allergic reaction which causes swelling of the face or throat(angioedema)

How To Manage Side Effects

!### Diarrhea

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do
not consume any medicine on your own without consulting your doctor. Consult
your doctor if symptoms do not show improvement.

!### Nausea And Vomiting

Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if
symptoms do not show improvement.

!### Stomach Pain

Try to rest and relax. Eat and drink slowly or try to have smaller meals. Keep a
heating pad on your stomach. If the symptom does not improve, contact your
doctor.

Warning & Precautions

!### Pregnancy

Use with CautionDALCINEX INJECTION should be used with caution in pregnant women or women
planning to have a baby. It will be given to you by the doctor only if it's
clearly necessary. Consult your doctor before receiving it.

!### Breastfeeding

Use with CautionDALCINEX INJECTION should be used with caution in breastfeeding women as it can
pass into breast milk. The breastfed infant can have diarrhea, fungal
infections, and hypersensitivity. Consult your doctor before receiving it.

!### Driving and Using Machines

Use with CautionDo not drive or use machines as DALCINEX INJECTION may cause mild to moderate
side effects like feeling dizzy, tired or headaches. Consult your doctor for
advice.

!### Kidney

Use with CautionDALCINEX INJECTION should be used with caution in patients with impaired kidney
problems. Consult your doctor before receiving it.

!### Liver

Use with CautionDALCINEX INJECTION should be used with caution in patients with impaired liver
problems. Consult your doctor before receiving it.

!### Allergy

ContraindicatedDo not receive DALCINEX INJECTION if you are allergic to Clindamycin or any
other ingredients of this medicine.

!### Use In Pediatrics

ContraindicatedDALCINEX INJECTION is not recommended for use in children below 12 years of age.
Consult your doctor before receiving DALCINEX INJECTION.

!### Use In Geriatrics

Use with CautionDALCINEX INJECTION should be used with caution in elderly patients above 60
years of age. consult your doctor before receiving DALCINEX INJECTION.

Others

Before receiving DALCINEX INJECTION, inform your doctor if you:

• Have problems with your muscle functions (Ex. myasthenia gravis (pathological muscular weakness) or Parkinson’s disease (shaking palsy)
• Have previously suffered from gastrointestinal diseases (Ex. inflammation of the colon)

Interactions

A. Drug-Drug interactions:

Before receiving DALCINEX INJECTION, inform your doctor if you are taking any of
the following medicine:

• Warfarin or similar medicines (Ex. acenocoumarol and fluindione) used to thin the blood.
• Muscle relaxants (Ex. cyclobenzaprine)
• Rifampicin (to manage tuberculosis)
• St John's wort (Hypericum perforatum) to manage depression
• Carbamazepine, phenytoin or phenobarbital (to manage epilepsy)
• Enzalutamide (manages prostate cancer), dabrafenib (cancer drug)
• Efavirenz (manages HIV/AIDS)

Overdosage:

DALCINEX INJECTION will be administered to you only by a doctor or a nurse in a
hospital, so it is unlikely to receive an overdose. However, consult your doctor
or nurse if you experience any unusual symptoms.

Synopsis

Drug	:	Clindamycin
Pharmacological Category	:	Lincosamides
Therapeutic Indication	:	Serious bacterial infections
Dosage Forms	:	Injection, Tablet, Capsule, Gel, Cream, Lotion, Solution, Spray, Soap

More Information

Storage

• Keep DALCINEX INJECTION out of reach of children
• Do not store above 25°C

FAQs About DALCINEX INJECTION

Q: What is DALCINEX INJECTION used for?

A: DALCINEX INJECTION is used to manage serious bacterial infections in adults
and adolescents above 12 years of age. Bacterial infection occurs when bacteria
enter the body, increasing in number and causing a reaction in the body.
Symptoms include fever, fatigue, headache, nausea, vomiting and swollen lymph
nodes in the neck, armpits, groin or elsewhere.

Q: Can I drive while receiving DALCINEX INJECTION?

A: Do not drive or use machines as DALCINEX INJECTION may cause mild to moderate
side effects like feeling dizzy, tiredness or headaches. Consult your doctor for
advice.

Q: How does DALCINEX INJECTION work?

A: DALCINEX INJECTION acts against the bacteria by binding to the 50S subunit of
the bacterial ribosome (site of protein synthesis). Which in turn manages
protein synthesis and kills the infection-causing bacteria.

Q: Can DALCINEX INJECTION be used in pregnancy?

A: DALCINEX INJECTION should be used with caution in pregnant women or women
planning to have a baby. It will be given to you by the doctor only if it's
clearly necessary. Consult your doctor before receiving it.

Q: Can DALCINEX INJECTION be used in children?

A: DALCINEX INJECTION is not recommended for use in children below 12 years of
age. Consult your doctor before receiving it for more information on safety
measures.

Useful Diagnostic Tests

• Complete blood count tests
• Liver function test
• Kidney function test