Calbloc 5mg Capsule 10'S

Introduction About CALBLOC 5MG CAPSULE

CALBLOC 5MG CAPSULE contains Nifedipine, which belongs to the group of medicines
called Antihypertensive drugs. It is used in the management of high blood
pressure (hypertension) and angina. Hypertension is a condition in which the
force of the blood against the blood vessel walls is too high and is
characterised by headache, irregular heartbeat, vision changes, a feeling of
overtiredness, nausea, vomiting, confusion, anxiety, and chest pain. Angina is a
type of chest pain caused by reduced blood flow to the heart and characterised
by a squeezing type of pain, pressure, heaviness, and tightness in the chest.

CALBLOC 5MG CAPSULE is not recommended for use in patients with liver and heart
disease and should be used with caution with patients having kidney dialysis,
improper liver function, or poor cardiac reserve. It should be used with caution
in pregnant women, and it is not recommended in a breast-feeding woman; consult
your doctor for advice.

CALBLOC 5MG CAPSULE is not recommended for use by children and adolescents below
18 years of age. The most common side effects of taking CALBLOC 5MG CAPSULE are
headache, flushing, a general feeling of being unwell, constipation, and
swelling, particularly of the ankles and legs. Consult your doctor if the
symptom worsens.

Uses Of CALBLOC 5MG CAPSULE

• Manage high blood pressure (hypertension) and angina (chest pain)

How CALBLOC 5MG CAPSULE Works

CALBLOC 5MG CAPSULE reduces blood pressure by relaxing and expanding the blood
vessels for easy blood flow and thereby lowers the blood pressure, which reduces
the strain on the heart. It also works by relaxing and expanding the blood
vessels supplying the heart, which allows more blood and oxygen to reach the
heart and decreases the strain on it. This reduces the severity and frequency of
angina attacks.

How to use CALBLOC 5MG CAPSULE

Take CALBLOC 5MG CAPSULE as advised by your physician. Swallow this medicine, do
not crush, or chew the medicine. Your doctor will decide the correct dose and
duration for you depending on your age, body weight and disease condition.

Side Effects Of CALBLOC 5MG CAPSULE

Common

• headache
• flushing
• general feeling of being unwell
• constipation
• swelling, especially of legs and ankle

Uncommon

• stomach pain
• unspecific pain
• chills
• low blood pressure when standing up showing symptoms of fainting, dizziness, lightheadedness, occasional palpitations, blurred vision, confusion
• fainting
• irregular heartbeat
• dry mouth
• indigestion
• wind (flatulence)
• feeling sick (nausea)
• muscle cramps
• joint swelling
• sleep disorders
• anxiety or nervousness
• reddening of the skin
• nose bleeds
• nasal congestion
• feeling of spinning (vertigo)
• migraine (one side headache)
• dizziness
• trembling (involuntary shaky movements)
• increased urge to urinate
• painful or difficult urination
• erection dysfunction (impotence)
• blurred vision

Rare

• pins and needles feeling
• gum inflammation, with swollen, tender or bleeding gums

Stop taking CALBLOC 5MG CAPSULE and contact your doctor immediately if you
experience any of the following side effects:

• generalised allergic reaction including very rarely life-threatening shock (Ex. difficulty in breathing, drop of blood pressure, fast pulse, swelling including airway
• other allergic reactions like swelling of the skin (sometimes severe which includes swelling of the larynx)
• fast heartbeat (tachycardia)
• shortness of breath or difficulty breathing
• mild to moderate allergic reactions
• itching, a rash or hives

How To Manage Side Effects

Constipation:

Eat plenty of fiber-rich foods, such as fresh fruits, vegetables, and cereals,
and drink plenty of water. Exercise more regularly.

Dizziness

When you feel dizzy, lie down or sit down immediately. If you're experiencing a
severe episode of vertigo, lie in a dark, quiet place with your eyes closed.
Vehicle driving should be avoided if you experience frequent dizziness without
warning. Talk to your doctor if the symptom worsens.

Headache:

Apply a hot or cold-water bag to your head. Try to take a rest in a quiet, dark
environment. Drink tea or coffee. Massage with mild pressure on the scalp or
head.

Dry mouth:

A dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free
hard candies to stimulate the flow of saliva. Drink water at regular intervals.
Do not use mouthwashes that contain alcohol because they can be drying.

Warning & Precautions

!### Pregnancy

CALBLOC 5MG CAPSULE should be used with caution during pregnancy but only after
special consideration done by your doctor. Consult your doctor before taking
CALBLOC 5MG CAPSULE.

!### Breastfeeding

CALBLOC 5MG CAPSULE is not recommended for use in breastfeeding women. Consult
your doctor for advice before taking [GBNKWYWORD].

!### Driving and Using Machines

Do not drive or operate any machines if you feel dizzy or sleepy, extremely
tired, faint, or have visual disturbances after taking CALBLOC 5MG CAPSULE.
Consult your doctor before taking CALBLOC 5MG CAPSULE.

!### Alcohol

Avoid consuming alcohol as it may cause dizziness, fainting, extreme tiredness,
or visual disturbances.

!### Kidney

CALBLOC 5MG CAPSULE should be taken with caution in patients undergoing kidney
dialysis. Consult your doctor before taking CALBLOC 5MG CAPSULE.

!### Liver

CALBLOC 5MG CAPSULE is not recommended for use in patients with liver disease
and should be used with caution when the liver is not working properly. Consult
your doctor before taking CALBLOC 5MG CAPSULE.

!### Allergy

CALBLOC 5MG CAPSULE is not recommended for use if you are allergic to
Nifedipine.

!### Heart Disease

CALBLOC 5MG CAPSULE is not recommended for use in patients who had a heart
attack, unstable angina, sudden angina attack, aortic stenosis (narrowing of the
aortic valve) and collapsed because of heart problems (cardiogenic shock).
CALBLOC 5MG CAPSULE should be taken with caution in patients having poor cardiac
reserve (the heart cannot cope with increased strain). Consult with your doctor.

Others

CALBLOC 5MG CAPSULE is not recommended for use if you have:

• inflammation of the bowel or intestines, such as Crohn’s disease
• obstruction or narrowing of intestines
• obstruction in the oesophagus (the tube connecting the throat to the stomach)
• Kock pouch (a surgically constructed intestinal reservoir with an opening through the abdominal wall) in your gut
• malignant hypertension (continuous rise in blood pressure despite management)

Before taking CALBLOC 5MG CAPSULE, inform your doctor if you have:

• low blood pressure
• diabetic

Use in pediatrics:

CALBLOC 5MG CAPSULE is not recommended for use in children and adolescents below
18 years of age. Consult your doctor before taking CALBLOC 5MG CAPSULE.

Interactions

A. Drug-Drug interactions:

• rifampicin (an antibiotic used to manage bacterial infections like tuberculosis)
• cimetidine (a medicine used to manage stomach ulcers)
• digoxin, diltiazem, quinidine, or beta-blockers like esmolol, and metoprolol (medicines used to manage heart conditions)
• quinupristin/dalfopristin (a combination antibiotic used to manage certain skin infections)
• phenytoin, carbamazepine or valproic acid (medicines used to manage epilepsy)
• cisapride (a medicine used to manage heartburn)
• magnesium sulphate injections during pregnancy (may cause a severe fall in blood pressure)
• erythromycin (a medicine used to manage or manage many infections)
• ketoconazole, itraconazole or fluconazole (medicines used to fungal infections)
• indinavir, nelfinavir, ritonavir, saquinavir or amprenavir (medicines used to manage hiv)
• fluoxetine or nefazodone (medicines used to manage depression)
• tacrolimus (a medicine used to manage the rejection of transplanted organs)
• phenobarbital (a medicine usually used to manage insomnia or anxiety)

B.  Drug - Food interaction:

Do not drink grapefruit juice or eat grapefruit while taking CALBLOC
5MG CAPSULE.

Overdosage:

If you or anyone else accidentally take too much of CALBLOC 5MG CAPSULE, consult
your doctor immediately or visit the nearby hospital. The most common symptoms
of overdose are low blood pressure, heartbeats may be increased or slowed down,
increased blood sugar level, increased acidity in the blood, swelling in the
lungs, low blood oxygen levels and disturbances in consciousness leading to
unconsciousness.

Synopsis

Drug	:	Nifedipine
Pharmacological Category	:	Calcium Channel Blockers
Therapeutic Indication	:	High Blood Pressure, Angina
Dosage Forms	:	Tablet, Capsule

More Information

• Keep CALBLOC 5MG CAPSULE out of reach from children
• Store at room temperature

FAQs About CALBLOC 5MG CAPSULE

Can CALBLOC 5MG CAPSULE be used to manage high blood pressure?

CALBLOC 5MG CAPSULE can be used to manage high blood pressure by relaxing and
expanding the blood vessels for easy blood flow and also reducing the strain on
the heart.

Can CALBLOC 5MG CAPSULE be used in patients with liver and kidney disease?

CALBLOC 5MG CAPSULE is not recommended for use in patients with liver disease
and should be used with caution when the liver is not working properly and the
patient is undergoing kidney dialysis. Consult your doctor before taking CALBLOC
5MG CAPSULE.

Can CALBLOC 5MG CAPSULE be given to children?

CALBLOC 5MG CAPSULE should not be used by children or adolescents under the age
of 18. Consult your doctor before taking CALBLOC 5MG CAPSULE.

Can CALBLOC 5MG CAPSULE be taken with food?

CALBLOC 5MG CAPSULE can be taken with or without food. But do not eat grapefruit
or drink grapefruit juice while taking CALBLOC 5MG CAPSULE.

Does CALBLOC 5MG CAPSULE cause constipation?

Constipation is one of the common side effects of CALBLOC 5MG CAPSULE. Eat
plenty of fiber-rich foods, such as fresh fruits, vegetables, and cereals, and
drink plenty of water to manage constipation. Exercise more regularly.

Useful Diagnostic Tests

• Electrocardiogram (ECG)