ARBLOCK M 25 Tablet 10's

Introduction About ARBLOCK M 25 TABLET

ARBLOCK M 25 TABLET is a medication used to manage hypertension (high blood
pressure). By lowering blood pressure, it reduces the risk of heart attacks and
strokes. It contains a combination of two medicines, metoprolol and telmisartan
which works together effectively to improve heart functions.

It is recommended to take ARBLOCK M 25 TABLET with food at the same time each
day to maintain consistent blood levels. Continue taking it as prescribed by
your doctor, even if you feel fine, since high blood pressure often presents no
symptoms. Stopping the medication abruptly can worsen your condition. Along with
the medicine, staying active, maintaining a healthy diet, and managing your
weight can further help control blood pressure. Always follow your doctor’s
guidance while on this therapy.

Common side effects include headache, weakness, dizziness, low blood pressure,
increased potassium levels, orthostatic hypotension (which may lead to
fainting), breathlessness, nausea, vomiting, abdominal pain, and fatigue. It is
advised to avoid potassium-rich foods or supplements while taking this medicine.
Since it can cause dizziness, avoid driving or get up slowly from a seated
position. Regular monitoring of blood pressure, blood sugar, kidney function,
urea, and electrolyte levels may be required during treatment.

Before starting this medicine, inform your doctor if you have any kidney or
liver issues. Pregnant or breastfeeding women should consult their doctor before
use. Also, let your doctor know about any other medications you are taking,
particularly those for blood pressure or heart conditions.

Uses Of ARBLOCK M 25 TABLET

• High blood pressure (hypertension)

Benefits of ARBLOCK M 25 TABLET in Hypertension:

• Effective Blood Pressure Control: Helps lower high blood pressure, reducing the risk of heart attacks, strokes, and other cardiovascular complications.
• Heart Health Support: Improves heart function and prevents further damage in patients with hypertension or heart disease.
• Improved Survival After Heart Attack: Early use enhances recovery and survival chances in patients who have suffered a heart attack.
• Protects Organs: Prevents damage to vital organs like the brain, heart, and kidneys caused by prolonged high blood pressure.
• Convenient Once-Daily Dosage: Easy-to-follow treatment schedule ensures consistent medication levels for o

How ARBLOCK M 25 TABLET Works

ARBLOCK M 25 TABLET helps in managing high blood pressure where metoprolol works
by managing certain chemical messengers to bind their respective receptors in
the heart and vessels, causing heart to beat slowly with less force and
telmisartan blocks the effect of angiotensin II receptor (a chemical messenger
that narrow down your blood vessels) that causes relaxation and widening of
blood vessels resulting in lowering of blood pressure.

How to use ARBLOCK M 25 TABLET

Take ARBLOCK M 25 TABLET as advised by your physician. Swallow the medicine with
a glass of water. Do not crush or chew the medicine.

Dosage and Administration

• The typical dose is one tablet daily, taken as prescribed by your doctor.
• The dosage may vary based on individual health conditions, age, and response to treatment. Always follow your doctor's instructions.
• Take the tablet at the same time each day to maintain consistent levels of the medication in your bloodstream.
• It can be taken with or without food, but taking it with food may help reduce side effects like nausea or dizziness.
• It should be taken regularly for long-term blood pressure control.
• Do not stop taking the medication abruptly, as it can lead to a rebound increase in blood pressure or heart rate.

Missed Dosage instructions for ARBLOCK M 25 TABLET:

• If you miss a dose take it as soon as you remember.
• If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Do not take a double dose to make up for the missed one, as this may increase the risk of side effects.

Overdosage instructions for ARBLOCK M 25 TABLET:

• Symptoms of overdose include severe dizziness, excessive drop in blood pressure, low or irregular heartbeat and breathing difficulties.
• In case of an overdose, seek immediate medical attention or call a poison control center. Overdosing on this medication can lead to life-threatening complications, including heart failure or circulatory collapse.

Side Effects Of ARBLOCK M 25 TABLET

Like all medicines, ARBLOCK M 25 TABLET may cause certain side effects, although
not everybody gets them.

The most common side effects of taking ARBLOCK M 25 TABLET are:

• Tiredness
• Dizziness
• Depression
• Shortness of breath
• Slow heartbeat
• Low blood pressure
• Diarrhoea
• Itchy skin
• Rash
• Vertigo (sudden internal or external spinning sensation)

When to consult your doctor?

• Sepsis (a life-threatening severe infection occurring due to damage of whole-body immune response)
• Angioedema (rapid and serious swelling of the skin and mucosa)

How To Manage Side Effects

!### Diarrhea

• Drink Fluids: Drink clear fluids such as water, broths, and oral rehydration solutions (ORS).
• Electrolytes: If you are losing a lot of fluids (for example, from frequent diarrhea), consider drinking an electrolyte solution to help replenish lost minerals like potassium and sodium.
• BRAT Diet: Try to take Bananas, Rice (white rice), Apple sauce and Toast (plain, without butter) to control diarrhoea management.
• Avoid Certain Foods: While recovering avoid the following food items such as fatty, greasy, or fried foods, spicy foods, dairy products (especially if you have a temporary lactose intolerance), caffeinated drinks and alcohol and artificial sweeteners like sorbitol.
• Over-the-Counter Medications: You can take over-the-counter anti-diarrheal medications such as loperamide, Bismuth subsalicylate if appropriate for you. Follow the recommended dosage.

!### Dizziness Or Drowsiness

• Sit or Lie Down: If you feel dizzy, sit down or lie down immediately to prevent falling. Keep your head still and close your eyes if needed.
• Hydrate: Dehydration can cause dizziness, so drink water or electrolyte-replenishing drinks like sports drinks.
• Avoid Sudden Movements: When standing or sitting, do so slowly to avoid triggering dizziness. Take your time when getting up.
• Eat Small, Regular Meals: Low blood sugar can cause dizziness, so eat small meals throughout the day and avoid skipping meals.
• Fresh Air: Sometimes dizziness can be alleviated by taking slow, deep breaths in a well-ventilated area.

Warning & Precautions

!### Pregnancy

ContraindicatedHuman and
components in this medicine) has shown to cause fetal harm. Therefore, ARBLOCK M
25 TABLET is not recommended for use in pregnant women. If you are pregnant or
think you may be pregnant consult your doctor for advice.

!### Breastfeeding

ContraindicatedARBLOCK M 25 TABLET is not recommended for use in breastfeeding women.
studies suggest that Telmisartan is excreted in breast milk and can lead to
potential adverse effects on the lactating neonate. Therefore, consult your
doctor before taking this medicine.

!### Driving and Using Machines

Use with CautionDo not drive or operate machines if you feel dizzy or tired after taking ARBLOCK
M 25 TABLET. Consult your doctor before taking ARBLOCK M 25 TABLET.

!### Alcohol

Consult your doctorAvoid consum
aggravate the low blood pressure.

!### Kidney

Consult your doctorARBLOCK M 25 TABLET is not recommended for use if have impaired kidney function
and managed with a blood pressure lowering medicine containing aliskiren. It
should be used with caution if you have certain kidney disease such as renal
artery stenosis (narrowing of the blood vessels to one or both kidneys) or have
undergone kidney transplant. Consult your doctor for advice before taking
ARBLOCK M 25 TABLET.

!### Liver

Consult your doctorARBLOCK M 25 TABLET is not recommended for use in patients with severe liver
problems such as cholestasis or biliary obstruction (disease causing difficulty
in drainage of the bile from the liver and gall bladder). It should be used with
caution in patients with liver diseases such as hepatic impairment. Consult your
doctor before taking ARBLOCK M 25 TABLET.

!### Allergy

ContraindicatedARBLOCK M 25 TABLET is not recommended for use if you are allergic to
metoprolol, telmisartan or any other ingredients of this medicine.

!### Lungs

Use with CautionARBLOCK M 25 TABLET should be used with caution in patients bronchospastic
disease (disease causing tightening of airway muscles) such as asthma,
emphysema, chronic obstructive pulmonary disease or lung infections. Consult
your doctor before taking ARBLOCK M 25 TABLET.

!### Heart Disease

Consult your doctorARBLOCK M 25 TABLET is not recommended for use in patients with heart disease
such as severe bradycardia (low heart rate), heart block greater than first
degree (condition in which heart beats very slowly or in abnormal rhythm),
cardiogenic shock (sudden life-threatening condition in which heart fails to
pump sufficient blood in the body), decompensated cardiac failure (inability of
heart to accommodate and/or eject sufficient blood) or sick sinus syndrome
(disorder of heart’s natural pacemaker). It should be used with caution in
patients having heart trouble. Consult your doctor for advice before taking
ARBLOCK M 25 TABLET.

!### Use In Pediatrics

ContraindicatedARBLOCK M 25 TABLET is not recommended for use in children and adolescents (aged
below 18 years).
affect kidney development and function. These studies indicated potential
adverse effects, including reduced renal perfusion and delayed renal maturation.
Consult your doctor before taking ARBLOCK M 25 TABLET.

!### Use In Geriatrics

Use with CautionARBLOCK M 25 TABLET should be used with caution in elderly patients (aged 65
years and above). Regular monitoring of renal and liver function tests is
advised. Consult your doctor before taking ARBLOCK M 25 TABLET.

Others

ARBLOCK M 25 TABLET is not recommended for use if you:

• Are planned for non-cardiac surgery

Before taking ARBLOCK M 25 TABLET, inform your doctor if you:

• Have pheochromocytoma (tumour of adrenal glands located on the kidneys)
• Have diabetes or hypoglycaemia (low blood sugar levels)
• Have history of anaphylactic reactions (signs include itching and flushed or pale skin, low blood pressure, nausea, vomiting)
• Have thyrotoxicosis (too high thyroid levels in the blood)
• Have peripheral vascular disease (flow to limbs due to narrowing of vessels)
• Raised aldosterone levels (water and salt retention in the body along with imbalance of various blood minerals)
• Low blood pressure due to dehydration (excessive loss of water from the body)
• Have deficiency of salt due to diuretic therapy (water tablets), low-salt diet, diarrhoea or vomiting
• Have elevated potassium levels in the blood

Safety Advice

• Always take ARBLOCK M 25 TABLET exactly as advised by your doctor to effectively manage hypertension.
• Regularly check your blood pressure at home to ensure the medication is working effectively.
• Do not stop taking ARBLOCK M 25 TABLET abruptly, as it may cause a sudden rise in blood pressure or other complications.
• Drink plenty of fluids, especially in hot weather, to prevent dehydration, which can lower blood pressure excessively.
• Limit salt intake and follow a balanced, heart-healthy diet for o
• Avoid alcohol consum
• Avoid Driving or Heavy Machinery: it may cause dizziness or fatigue, especially when starting the treatment. Avoid tasks requiring alertness until you know how it affects you.
• Not recommended for use during pregnancy or breastfeeding. Consult your doctor immediately if you become pregnant while taking this medication.
• Seek immediate medical attention if you accidentally take more than the prescribed dose, as it may cause severe dizziness, fainting, or a slow heartbeat.
• Start with a lower dose if prescribed for elderly patients, as they are more susce
• Visit your doctor for regular blood tests to monitor potassium levels, kidney function, and overall response to the medication.

Drug - Drug interaction

1. Interactions with Antihypertensive MedicationsOther RAAS Inhibitors (e.g., ACE inhibitors or ARBs): Co-administration can
   increase the risk of hyperkalemia, kidney dysfunction, or hypotension. Regular
   monitoring of potassium levels and renal function is recommended.

Diuretics (e.g., Furosemide, Hydrochlorothiazide): Co-administration may
lead to an excessive drop in blood pressure, especially after the first dose,
due to synergistic antihypertensive effects.

2. Interactions with Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

Drugs like Ibuprofen, Naproxen, or Aspirin can reduce the antihypertensive
effect of this tablet

Long-term use of NSAIDs with Telmisartan can impair renal function and increase
the risk of renal failure, particularly in elderly patients or those with
existing kidney disease.

3. Interactions with Antidiabetic Medications

Telmisartan may enhance the blood sugar-lowering effects of insulin or oral
antidiabetic drugs, increasing the risk of hypoglycemia.

Metoprolol can mask symptoms of hypoglycemia, such as tachycardia, which may
delay treatment in diabetic patients.

4. Interactions with Drugs Affecting Potassium LevelsPotassium-Sparing Diuretics (e.g., Spironolactone, Amiloride) or Potassium
   Supplements: Telmisartan may increase potassium levels, leading to
   hyperkalemia, a condition characterized by muscle weakness, fatigue, and
   irregular heart rhythms.

5. Interactions with Calcium Channel Blockers

Amlodipine or other calcium channel blockers combined with Metoprolol may result
in an additive effect, leading to severe bradycardia, hypotension, or dizziness.

6. Interactions with Antiarrhythmic DrugsAmiodarone or Digoxin: Metoprolol’s beta-blocking properties may
   increase the risk of severe bradycardia or conduction disturbances. Digoxin
   levels should be monitored, as they may rise due to Telmisartan.

7. Interactions with CNS DepressantsSedatives, antidepressants (e.g., SSRIs), or antipsychotics:
   Metoprolol may amplify the sedative effects of these drugs, causing excessive
   drowsiness, fatigue, or dizziness.

8. Interactions with Lipid-Lowering MedicationsStatins (e.g., Atorvastatin, Rosuvastatin): Metoprolol metabolism may be
   affected, increasing the risk of muscle pain or rhabdomyolysis.

Synopsis

Drug	:	Metoprolol, Telmisartan
Pharmacological Category	:	Beta-blockers, Angiotensin II receptor antagonists
Therapeutic Indication	:	Hypertension (high blood pressure)
Dosage Forms	:	Tablet

More Information

Onset of action: The combination of Telmisartan and Metoprolol usually
begins to show effects within 1–3 hours after administration, targeting both
high blood pressure and heart rate effectively.

Durationof action: The combined action lasts for a full 24 hours,
ensuring consistent blood pressure and heart rate management with once-daily
dosing.

FAQs About ARBLOCK M 25 TABLET

Q: What is ARBLOCK M 25 TABLET used for?

A: ARBLOCK M 25 TABLET is used to manage hypertension. Hypertension is an
abnormal condition in which blood pressure rises higher than normal limits in
the blood vessels. It is characterized by severe headache, nose bleeding,
weakness, disturbed vision, chest pain and shortness of breath.

Q: What happens if you take more ARBLOCK M 25 TABLET than your required dose?

A: If you or anyone else accidentally takes too much of ARBLOCK M 25 TABLET,
consult your doctor immediately or visit the nearby hospital. Symptoms of
overdose are low blood pressure, fast or slow heartbeat, dizziness, heart block,
heart failure, bronchospasm (constriction of lung muscles), hypoxia (lack of
oxygen supply to body cells), higher levels of creatinine in the blood, sudden
kidney failure, impairment of consciousness or nausea, vomiting and coma.

Q: What side effects are seen with ARBLOCK M 25 TABLET?

A: The common side effects associated with the use of ARBLOCK M 25 TABLET are
low blood pressure, tiredness, dizziness, depression, diarrhoea, shortness of
breath, slow heartbeat and rash. Consult your doctor if any of the side effect
worsens.

Q: Who should avoid taking ARBLOCK M 25 TABLET?

A: ARBLOCK M 25 TABLET is not recommended for use if you are having asthma,
emphysema, chronic obstructive pulmonary disease, lung infections, cholestasis
or biliary obstruction, impaired kidney function, severely low heart rate, heart
block, cardiogenic shock, decompensated cardiac failure or sick sinus syndrome.
It is also not recommended for use in pregnant and breastfeeding women, children
and adolescents (aged below18 years). Consult your doctor before taking ARBLOCK
M 25 TABLET.

Q: Is ARBLOCK M 25 TABLET safe to use in children?

A: ARBLOCK M 25 TABLET is not recommended for use in children and adolescents
(aged below 18 years). If ARBLOCK M 25 TABLET is accidentally ingested by a
child or adolescent, go to the hospital immediately and consult the doctor for
further management.

Q: Can I drink alcohol while taking ARBLOCK M 25 TABLET?

A: Avoid consum
aggravate the low blood pressure. However, if you are habitual of drinking
alcohol, you must consult your doctor before taking this medicine.

Q: Is ARBLOCK M 25 TABLET safe to use in patients with kidney problems?

A: ARBLOCK M 25 TABLET is not recommended for use if have impaired kidney
function and managed with a blood pressure lowering medicine containing
aliskiren. It should be used with caution if you have certain kidney disease
such as renal artery stenosis (narrowing of the blood vessels to one or both
kidneys) or have undergone kidney transplant. Consult your doctor for advice
before taking ARBLOCK M 25 TABLET.

Useful Diagnostic Tests

• Cardiac Risk Profile
• Lipid Profile
• Kidney Function Test