APNICAF Oral Solution 3ml

Introduction About APNICAF ORAL SOLUTION

APNICAF ORAL SOLUTION contains Caffeine which belongs to the group of medicines
called CNS stimulants. It is used to manage primary apnea (episodes of
interrupted breathing) in premature babies. Primary apnea in premature babies
happens due to immature development of baby’s breathing centers.

APNICAF ORAL SOLUTION has been shown to reduce the number of episodes of
interrupted breathing in premature newborns babies. It can also be used to
manage bronchopulmonary dysplasia (airway damage) among premature babies.

Before APNICAF ORAL SOLUTION is administered, inform your doctor if you child
has any liver, kidney or heart problems. You must also inform your doctor if
your child suffers from seizure disorders, slow weight gain or frequent
regurgitation (spitting up of milk or food) as a precaution.

If you are the mother of the premature infant who receives the management, you
must not drink coffee or take foods which has high caffeine content. This is
because the caffeine taken by the breastfeeding mother may pass through the
breast milk to the nursing premature infant who is already receiving caffeine
therapy and may lead to an overdosage. The most common side effect of APNICAF
ORAL SOLUTION is fast or irregular heart rate. Consult your doctor if it
worsens.

Uses Of APNICAF ORAL SOLUTION

• Manage primary apnea (episodes of interrupted breathing) in premature babies
• Manage and manages bronchopulmonary dysplasia (airway damage) in premature babies

How APNICAF ORAL SOLUTION Works

APNICAF ORAL SOLUTION is a CNS stimulant. It works by stimulating a part of the
brain that controls breathing. As a result, the brain transfers a lot of
breathing signals to the lungs which makes the lungs breathe more deeper and
faster. It also increases the number of breathing cycles, manages the airway
damage and reduces the need for mech

How to use APNICAF ORAL SOLUTION

APNICAF ORAL SOLUTION will be administered orally (via gastric feeding tube) to
your child only by a doctor or a nurse.

Your doctor will decide the correct dose and duration of therapy for your child
based on their gestational age, body weight and health condition.

Side Effects Of APNICAF ORAL SOLUTION

Common

• Fast or irregular heart rate
• Increased blood sugar levels

Contact your doctor immediately if you notice any of the following side effects
in your child after APNICAF ORAL SOLUTION is administered:

• Severe bloody stools
• Fits
• Blood infections (sepsis)
• Allergic reactions (such as skin rash, itching, redness, swelling of the face, lips, tongue or threating and breathing difficulties)

Warning & Precautions

!### Breastfeeding

ContraindicatedIf you are the mother of the premature infant who receives the management, you
must not drink coffee or take foods which has high caffeine content. This is
because the caffeine taken by the breastfeeding mother may pass through the
breast milk to the nursing premature infant who is already receiving caffeine
therapy and may lead to an overdosage.

!### Kidney

Use with CautionAPNICAF ORAL SOLUTION should be used with caution in babies with kidney
problems. Therefore, inform your doctor as a precaution.

!### Liver

Use with CautionAPNICAF ORAL SOLUTION should be used with caution in babies with liver problems.
Therefore, inform your doctor as a precaution.

!### Allergy

ContraindicatedIf your child is allergic to caffeine, kindly inform your doctor before APNICAF
ORAL SOLUTION is administered to the child.

!### Heart Disease

Use with CautionAPNICAF ORAL SOLUTION should be used with caution in babies with heart problems
(such as irregular heart rate). Therefore, inform your doctor as a precaution.

!### Use In Pediatrics

SafeAPNICAF ORAL SOLUTION can be used in premature infants born between 28-33
gestation weeks (7-8 months of pregnancy) under careful medical supervision.

Others

Before APNICAF ORAL SOLUTION is administered to the baby, kindly inform the
doctor if your baby suffers from any of the following conditions:

• fits
• frequent regurgitation (spitting up of milk or food)
• increased urination
• slow or reduced weight gain or food intake
• increased caffeine intake by the mother before the baby is delivered
• use of antiepile

Interactions

A. Drug-Drug interactions:

Before APNICAF ORAL SOLUTION is administered to the child, kindly inform the
doctor if your child is given any of the following medicines as a precaution:

• other medicines that help in breathing (Ex. theophylline, doxapram)
• medicines used to control fits (such as phenobarbitone or phenytoin) taken by the mother during pregnancy before delivering the baby
• ketoconazole (a medicine used to manage fungal infections)
• medicines used to manage stomach ulcers (such as omeprazole, pantoprazole, rabeprazole, r

Overdosage:

APNICAF ORAL SOLUTION will be administered only by a doctor or a nurse in a
hospital, and so it is unlikely to receive an overdose. However, consult your
doctor if you notice fits or any other side effects in your child.

Synopsis

Drug	:	Caffeine
Pharmacological Category	:	Methylxanthines
Therapeutic Indication	:	Apnea of prematurity in infants
Dosage Forms	:	Tablet, Injection, Oral solution, Suspension

More Information

• Keep APNICAF ORAL SOLUTION out of reach of children
• Store APNICAF ORAL SOLUTION at room temperature

FAQs About APNICAF ORAL SOLUTION

Q: What is the use of APNICAF ORAL SOLUTION?A: APNICAF ORAL SOLUTION is used to manage primary apnea (episodes of
interrupted breathing) in premature babies. It can also be used to manage
bronchopulmonary dysplasia (airway damage) among premature babies.

Q: How APNICAF ORAL SOLUTION helps in breathing problems?A: APNICAF ORAL SOLUTION is a CNS stimulant. It works by stimulating a part
of the brain that controls breathing. As a result, the brain transfers a lot of
breathing signals to the lungs which makes the lungs breathe more deeper and
faster. It also increases the number of breathing cycles, manages the airway
damage and reduces the need for mech

Q: Is APNICAF ORAL SOLUTION safe for use in children?A: APNICAF ORAL SOLUTION can be used in premature infants born between 28-33
gestation weeks (7-8 months of pregnancy) under careful medical supervision.

Q: Why newborn babies suffer from apnea?A: Primary apnea in premature babies happens due to immature development of
baby’s breathing centers.

Q:  What are the side effects of APNICAF ORAL SOLUTION?A: The most common side effect of APNICAF ORAL SOLUTION is fast or irregular
heart rate. Consult your doctor if it worsens.

Q: Is APNICAF ORAL SOLUTION effective?A: APNICAF ORAL SOLUTION effectively improves breathing among infants
suffering from apnea of prematurity. It works by stimulating a part of the brain
that controls breathing. It also increases the number of breathing cycles,
manages the airway damage and reduces the need for mech