Amlobet Tablet 14'S

Introduction About AMLOBET TABLET

AMLOBET TABLET is used to manage hypertension and angina pectoris (chest pain
caused due to lack of oxygen supply to the heart). It can also be used to reduce
the risk of heart attack (myocardial infarction) among heart patients.

It contains a combination of Amlodipine and Atenolol which belongs to the group
of medicine called Antihypertensive agents.

Take AMLOBET TABLET as advised by your physician. Avoid drinking grapefruit
juice while taking AMLOBET TABLET, as it could further decrease your blood
pressure and may make you feel dizzier, drowsier or faint.

Before taking AMLOBET TABLET, inform your doctor if you have any liver or kidney
problems. You must also inform your doctor if you have asthma, diabetes,
overactive thyroid gland or low blood volume as a precaution.

AMLOBET TABLET is not recommended for use in patients with other severe heart
problems apart from hypertension and angina (such as heart failure). It is also
not suitable for use in patients with severe hypotension (low blood pressure).

Consult your doctor before taking AMLOBET TABLET if you are pregnant or
breastfeeding. The most common side effects of taking AMLOBET TABLET are
swelling of ankles or other body parts, headache, dizziness, sleepiness,
tiredness, racing heartbeat, indigestion, constipation, muscle cramps, cold
hands and feet and slow heartbeat. Contact your doctor if any of these side
effects trouble you.

Uses Of AMLOBET TABLET

AMLOBET TABLET is used in the management of the following cardiac conditions:

• Hypertension (high blood pressure)
• Angina (chest pain)

How AMLOBET TABLET Works

AMLOBET TABLET contains two medicines namely amlodipine and atenolol. Atenolol
blocks the effects of certain hormones (adrenaline) in the body that naturally
increases heart rate. This slows down the heartbeat and makes the heart to pump
blood with a lesser force.

Amlodipine is a vasodilator. It relaxes the blood vessels supplying the heart
which improves blood flow and oxygen supply to the heart muscles. Collectively,
they reduce the strain on the heart and improves heart functions.

How to use AMLOBET TABLET

• Take AMLOBET TABLET as advised by your physician.
• Swallow the medicines with a glass of water. Do not crush or chew the medicine.
• AMLOBET TABLET can be taken with or without meals.
• Your doctor will prescribe the correct dosage and duration based on your health condition.
• Do not stop taking the medication abruptly without consulting your doctor, even if you feel better.

Side Effects Of AMLOBET TABLET

Like all medicines, AMLOBET TABLET may cause side effects in some individuals,
although not everyone gets them.

Common Side Effects of AMLOBET TABLET:

• edema (swelling of the ankles or other body parts)
• headache, dizziness, sleepiness
• palpitations (fast heartbeat)
• flushing (redness and warmth of the skin)
• stomach pain, nausea, diarrhea, constipation, indigestion
• changes in bowel habit
• tiredness, weakness
• muscle pains
• cold hands and feet
• slow heartbeat
• insomnia (sleeplessness)
• changes in taste
• tingling sensation in limbs, loss of pain sensation
• low blood pressure
• increased sweating
• increased urination at night
• inability to obtain an erection, enlargement of the breasts in men
• joint pain, back pain
• weight gain or decrease in weight

Stop taking AMLOBET TABLET and contact your doctor immediately if you experience
any of the following side effects:

• chest pain, shortness of breath (signs of heart attack)
• inflammation of pancreas (causing severe stomach pain that radiates to the back side of the body)

Warning & Precautions

!### Pregnancy

Monitoring requiredAMLOBET TABLET should be used in pregnant women only if it is considered
necessary by the physician. Therefore, consult your doctor before taking it.

!### Breastfeeding

Use with CautionAMLOBET TABLET should be used with caution in breastfeeding women as it may pass
through the breast milk to the nursing infant. Therefore, consult your doctor
before taking it.

!### Driving and Using Machines

Use with CautionDo not drive or operate any heavy tools or machines if you feel dizzy after
taking AMLOBET TABLET.

!### Alcohol

Consult your doctorAvoid consum
feel dizzier.

!### Kidney

Use with CautionAMLOBET TABLET should be used with caution in patients with kidney problems
(such as dialysis). Therefore, consult your doctor before taking it.

!### Liver

Use with CautionAMLOBET TABLET should be used with caution in patients with liver problems.
Therefore, consult your doctor before taking it.

!### Allergy

ContraindicatedDo not take AMLOBET TABLET if you are allergic to Atenolol, Amlodipine or to any
other beta blockers (such as propranolol) or calcium antagonists (such as
nifedipine, diltiazem).

!### Lungs

Use with CautionAMLOBET TABLET should be used with caution in patients who have or previously
had any breathing problems such as asthma. Therefore, consult your doctor before
taking it.

!### Heart Disease

Consult your doctorAMLOBET TABLET is not recommended for use in patients with severe heart problems
such as heart failure, aortic stenosis (narrowing of arteries) or cardiogenic
shock (inability of heart to pump blood). It should be used with caution in
patients having a history of recent heart attack or heart failure. Therefore,
consult your doctor before taking it.

!### Use In Pediatrics

ContraindicatedAMLOBET TABLET is not recommended for use in children and adolescents (aged
below 18 years) due to lack of safety data. Therefore, consult your doctor for
advice.

!### Use In Geriatrics

Use with CautionAMLOBET TABLET should be used with caution in the elderly patients. Therefore,
consult your doctor before taking it.

Others

AMLOBET TABLET is not recommended for use if you:

• have severe low blood pressure (hypotension)
• have a very poor blood circulation
• have unmanaged phaeochromocytoma (a tumor present in the adrenal gland)
• have metabolic acidosis (high acid levels in the blood)

Before taking AMLOBET TABLET, inform your doctor if you:

• have severe uncontrollable increase in blood pressure (hypertensive crisis)
• have diabetes
• have low blood volume (loss of fluids from the body due to vomiting or diarrhea)
• have thyrotoxicosis (increased activity of the thyroid gland)
• have psoriasis (an autoimmune skin condition causing white patches)
• any scheduled for any operations or procedures

Interactions

A. Drug-Drug interactions:

Before taking AMLOBET TABLET, inform your doctor if you are taking any of the
following medicines such as:

• other medicines used to manage high blood pressure and angina (such as nifedipine, verapamil, diltiazem, enalapril, ramipril, metoprolol, clonidine)
• ketoconazole, itraconazole (used to manage fungal infections)
• ritonavir, indinavir, nelfinavir (used in management of HIV infections)
• rifampicin, erythromycin, clarithromycin (used to manage bacterial infections)
• dantrolene (a medicine used to manage muscle spasms)
• medicines used to control elevated cholesterol levels (Ex. simvastatin)
• medicines used to manage graft rejection and to suppress immune functions (such as tacrolimus, sirolimus, temsirolimus, everlimus, cyclosporine)
• St. John’s wort (an herbal medicine used to manage depression)
• medicine used to manage irregular heartbeat (Ex. amiodarone, digoxin, quinidine or disopyramide)
• adrenaline (a medicine used to stimulate the heart)
• indomethacin or ibuprofen (medicines used for pain relief)
• medicines used to manage nose or sinus congestion and other cold remedies (such as montelukast, levocetirizine)
• medicines used to manage diabetes (Ex. insulin, metformin, glimepiride)

B. Drug-Food interaction:

Avoid drinking grapefruit juice while taking AMLOBET TABLET, as it could lead to
further decrease your blood pressure and may make you feel dizzier, drowsier or
faint.

Overdosage:

If you or anyone else accidentally took more AMLOBET TABLET, consult your doctor
immediately or visit the nearby hospital. Symptoms of overdosage might include
dizziness, fainting, light-headedness, weakness, shock, cool or clampy skin and
shortness of breath.

Synopsis

Drug	:	Amlodipine, Atenolol
Pharmacological Category	:	Calcium Channel Blocker, Beta blockers
Therapeutic Indication	:	Hypertension, Angina pectoris
Dosage Forms	:	Tablet, Capsule, Tabcap, Captab

More Information

Storage

• Keep AMLOBET TABLET out of the sight and reach of children
• Store AMLOBET TABLET at room temperature

FAQs About AMLOBET TABLET

Q: What are the uses of AMLOBET TABLET?

A: AMLOBET TABLET is used to manage hypertension (also known as high blood
pressure) and angina pectoris (chest pain caused by a lack of oxygen supply to
the heart). By controlling blood pressure and improving oxygen supply to the
heart, this medicine can also contribute to protect your heart from heart
failure if you are suffering from previous history of heart attack.

Q: What type of medicine is AMLOBET TABLET?

A: AMLOBET TABLET is an antihypertensive medicine. Atenolol blocks the effects
of certain hormones (adrenaline) in the body that naturally increase heart rate.
This slows down the heartbeat and makes the heart pump blood with less force.
Amlodipine is a vasodilator. It relaxes the blood vessels supplying the heart,
which improves blood flow and oxygen supply to the heart muscles. Collectively,
they reduce the strain on the heart and improve heart function.

Q: How do I take AMLOBET TABLET?

A: Take AMLOBET TABLET as advised by your physician. Swallow the medicines with
a glass of water. Do not crush or chew the medicine. AMLOBET TABLET can be taken
with or without meals. Your doctor will decide the correct dose and duration for
you depending on your age, body weight, and disease condition. Continue to take
AMLOBET TABLET for the stipulated duration instructed by your doctor to achieve
better results.

Q: What should I do if I forget to take a dose of AMLOBET TABLET?

A: If you have missed a dose of AMLOBET TABLET, take it as soon as you remember.
However, if it is time for the next dose of AMLOBET TABLET, skip the missed dose
and take the next one regularly. Do not take a double dose of AMLOBET TABLET to
compensate for the missed ones.

Q: What precautions should be followed while taking AMLOBET TABLET?

A: Before taking AMLOBET TABLET, inform your doctor if you have any liver or
kidney problems. You must also inform your doctor if you have severe high or low
blood pressure or other heart problems (such as narrowing of the arteries,
cardiogenic shock, or a recent heart attack). Consult your doctor before taking
AMLOBET TABLET if you are pregnant and breastfeeding. Regularly visit your
doctor and take all the necessary blood tests recommended by your doctor without
fail.

Q: Can I consume alcohol while taking AMLOBET TABLET?

A: Avoid consum
you feel dizzy.

Q: What happens if I accidentally take more AMLOBET TABLET?

A: If you or anyone else accidentally took more AMLOBET TABLET, consult your
doctor immediately. Symptoms of overdosage might include dizziness, fainting,
light-headedness, weakness, shock, cool or clampy skin, and shortness of breath.

Q: Can AMLOBET TABLET cause ankle swelling?

A: AMLOBET TABLET may cause edema or swelling of the ankles in a few patients.
If you experience ankle swelling, keep your legs on a table or slightly elevated
from ground level. If this symptom bothers you, contact your doctor.

Q: What are the side effects of AMLOBET TABLET?

A: The most common side effects of taking AMLOBET TABLET are swelling of ankles
or other body parts, headache, dizziness, sleepiness, tiredness, racing
heartbeat, indigestion, constipation, muscle cramps, cold hands and feet, and a
slow heartbeat. Contact your doctor if any of these side effects trouble you.

Q: Can I stop taking AMLOBET TABLET suddenly?

A: No. Do not stop taking AMLOBET TABLET without consulting your doctor. As
hypertension is a chronic condition, long term management may be necessary to
control its symptoms. Therefore, take AMLOBET TABLET as advised by your doctor
for the stipulated duration. Premature discontinuation of therapy may increase
your blood pressure once again.

Q: Can AMLOBET TABLET be taken during pregnancy?

A: AMLOBET TABLET should be used in pregnant women only if it is considered
necessary by the physician. Therefore, consult your doctor before taking it.

Q: Can AMLOBET TABLET be taken during breastfeeding?

A: AMLOBET TABLET should be used with caution in breastfeeding women as it may
pass through the breast milk to the nursing infant. Therefore, consult your
doctor before taking it.

Q: Can I take other medicines with AMLOBET TABLET?

A: Before taking AMLOBET TABLET, inform your doctor if you are taking, have
taken, or might take any other medicine, including prescri
non-prescri
other and cause serious side effects.

Q: Can the use of AMLOBET TABLET affect the liver?

A: Yes. AMLOBET TABLET should be used with caution in patients with liver
problems. Consult your doctor before taking it.

Q: Can AMLOBET TABLET cause erectile dysfunction?

A: AMLOBET TABLET may cause problems in erection in a few individuals. Consult
your doctor if it bothers you.

Q: Is AMLOBET TABLET safe to use in patients with heart problems?

A: AMLOBET TABLET is not recommended for use in patients with severe heart
problems such as heart failure, aortic stenosis (narrowing of arteries), or
cardiogenic shock (inability of the heart to pump blood). It should be used with
caution in patients with a history of recent heart attacks or heart failure.
Therefore, consult your doctor before taking it.

Useful Diagnostic Tests

• Kidney function test
• Cardiac Risk Profile