AMLOACT AT Tablet 10's

Introduction About AMLOACT AT TABLET

AMLOACT AT TABLET is used to manage hypertension and angina pectoris (chest pain
caused due to lack of oxygen supply to the heart). It can also be used to reduce
the risk of heart attack (myocardial infarction) among heart patients.

It contains a combination of Amlodipine and Atenolol which belongs to the group
of medicine called Antihypertensive agents.

Take AMLOACT AT TABLET as advised by your physician. Avoid drinking grapefruit
juice while taking AMLOACT AT TABLET, as it could further decrease your blood
pressure and may make you feel dizzier, drowsier or faint.

Before taking AMLOACT AT TABLET, inform your doctor if you have any liver or
kidney problems. You must also inform your doctor if you have asthma, diabetes,
overactive thyroid gland or low blood volume as a precaution.

AMLOACT AT TABLET is not recommended for use in patients with other severe heart
problems apart from hypertension and angina (such as heart failure). It is also
not suitable for use in patients with severe hypotension (low blood pressure).

Consult your doctor before taking AMLOACT AT TABLET if you are pregnant or
breastfeeding. The most common side effects of taking AMLOACT AT TABLET are
swelling of ankles or other body parts, headache, dizziness, sleepiness,
tiredness, racing heartbeat, indigestion, constipation, muscle cramps, cold
hands and feet and slow heartbeat. Contact your doctor if any of these side
effects trouble you.

Uses Of AMLOACT AT TABLET

AMLOACT AT TABLET is used in the management of the following cardiac conditions:

• Hypertension (high blood pressure)
• Angina (chest pain)

How AMLOACT AT TABLET Works

AMLOACT AT TABLET contains two medicines namely amlodipine and atenolol.
Atenolol blocks the effects of certain hormones (adrenaline) in the body that
naturally increases heart rate. This slows down the heartbeat and makes the
heart to pump blood with a lesser force.

Amlodipine is a vasodilator. It relaxes the blood vessels supplying the heart
which improves blood flow and oxygen supply to the heart muscles. Collectively,
they reduce the strain on the heart and improves heart functions.

How to use AMLOACT AT TABLET

• Take AMLOACT AT TABLET as advised by your physician.
• Swallow the medicines with a glass of water. Do not crush or chew the medicine.
• AMLOACT AT TABLET can be taken with or without meals.
• Your doctor will prescribe the correct dosage and duration based on your health condition.
• Do not stop taking the medication abruptly without consulting your doctor, even if you feel better.

Side Effects Of AMLOACT AT TABLET

Like all medicines, AMLOACT AT TABLET may cause side effects in some
individuals, although not everyone gets them.

Common Side Effects of AMLOACT AT TABLET:

• edema (swelling of the ankles or other body parts)
• headache, dizziness, sleepiness
• palpitations (fast heartbeat)
• flushing (redness and warmth of the skin)
• stomach pain, nausea, diarrhea, constipation, indigestion
• changes in bowel habit
• tiredness, weakness
• muscle pains
• cold hands and feet
• slow heartbeat
• insomnia (sleeplessness)
• changes in taste
• tingling sensation in limbs, loss of pain sensation
• low blood pressure
• increased sweating
• increased urination at night
• inability to obtain an erection, enlargement of the breasts in men
• joint pain, back pain
• weight gain or decrease in weight

Stop taking AMLOACT AT TABLET and contact your doctor immediately if you
experience any of the following side effects:

• chest pain, shortness of breath (signs of heart attack)
• inflammation of pancreas (causing severe stomach pain that radiates to the back side of the body)

Warning & Precautions

!### Pregnancy

Monitoring requiredAMLOACT AT TABLET should be used in pregnant women only if it is considered
necessary by the physician. Therefore, consult your doctor before taking it.

!### Breastfeeding

Use with CautionAMLOACT AT TABLET should be used with caution in breastfeeding women as it may
pass through the breast milk to the nursing infant. Therefore, consult your
doctor before taking it.

!### Driving and Using Machines

Use with CautionDo not drive or operate any heavy tools or machines if you feel dizzy after
taking AMLOACT AT TABLET.

!### Alcohol

Consult your doctorAvoid consum
feel dizzier.

!### Kidney

Use with CautionAMLOACT AT TABLET should be used with caution in patients with kidney problems
(such as dialysis). Therefore, consult your doctor before taking it.

!### Liver

Use with CautionAMLOACT AT TABLET should be used with caution in patients with liver problems.
Therefore, consult your doctor before taking it.

!### Allergy

ContraindicatedDo not take AMLOACT AT TABLET if you are allergic to Atenolol, Amlodipine or to
any other beta blockers (such as propranolol) or calcium antagonists (such as
nifedipine, diltiazem).

!### Lungs

Use with CautionAMLOACT AT TABLET should be used with caution in patients who have or previously
had any breathing problems such as asthma. Therefore, consult your doctor before
taking it.

!### Heart Disease

Consult your doctorAMLOACT AT TABLET is not recommended for use in patients with severe heart
problems such as heart failure, aortic stenosis (narrowing of arteries) or
cardiogenic shock (inability of heart to pump blood). It should be used with
caution in patients having a history of recent heart attack or heart failure.
Therefore, consult your doctor before taking it.

!### Use In Pediatrics

ContraindicatedAMLOACT AT TABLET is not recommended for use in children and adolescents (aged
below 18 years) due to lack of safety data. Therefore, consult your doctor for
advice.

!### Use In Geriatrics

Use with CautionAMLOACT AT TABLET should be used with caution in the elderly patients.
Therefore, consult your doctor before taking it.

Others

AMLOACT AT TABLET is not recommended for use if you:

• have severe low blood pressure (hypotension)
• have a very poor blood circulation
• have unmanaged phaeochromocytoma (a tumor present in the adrenal gland)
• have metabolic acidosis (high acid levels in the blood)

Before taking AMLOACT AT TABLET, inform your doctor if you:

• have severe uncontrollable increase in blood pressure (hypertensive crisis)
• have diabetes
• have low blood volume (loss of fluids from the body due to vomiting or diarrhea)
• have thyrotoxicosis (increased activity of the thyroid gland)
• have psoriasis (an autoimmune skin condition causing white patches)
• any scheduled for any operations or procedures

Interactions

A. Drug-Drug interactions:

Before taking AMLOACT AT TABLET, inform your doctor if you are taking any of the
following medicines such as:

• other medicines used to manage high blood pressure and angina (such as nifedipine, verapamil, diltiazem, enalapril, ramipril, metoprolol, clonidine)
• ketoconazole, itraconazole (used to manage fungal infections)
• ritonavir, indinavir, nelfinavir (used in management of HIV infections)
• rifampicin, erythromycin, clarithromycin (used to manage bacterial infections)
• dantrolene (a medicine used to manage muscle spasms)
• medicines used to control elevated cholesterol levels (Ex. simvastatin)
• medicines used to manage graft rejection and to suppress immune functions (such as tacrolimus, sirolimus, temsirolimus, everlimus, cyclosporine)
• St. John’s wort (an herbal medicine used to manage depression)
• medicine used to manage irregular heartbeat (Ex. amiodarone, digoxin, quinidine or disopyramide)
• adrenaline (a medicine used to stimulate the heart)
• indomethacin or ibuprofen (medicines used for pain relief)
• medicines used to manage nose or sinus congestion and other cold remedies (such as montelukast, levocetirizine)
• medicines used to manage diabetes (Ex. insulin, metformin, glimepiride)

B. Drug-Food interaction:

Avoid drinking grapefruit juice while taking AMLOACT AT TABLET, as it could lead
to further decrease your blood pressure and may make you feel dizzier, drowsier
or faint.

Overdosage:

If you or anyone else accidentally took more AMLOACT AT TABLET, consult your
doctor immediately or visit the nearby hospital. Symptoms of overdosage might
include dizziness, fainting, light-headedness, weakness, shock, cool or clampy
skin and shortness of breath.

Synopsis

Drug	:	Amlodipine, Atenolol
Pharmacological Category	:	Calcium Channel Blocker, Beta blockers
Therapeutic Indication	:	Hypertension, Angina pectoris
Dosage Forms	:	Tablet, Capsule, Tabcap, Captab

More Information

Storage

• Keep AMLOACT AT TABLET out of the sight and reach of children
• Store AMLOACT AT TABLET at room temperature

FAQs About AMLOACT AT TABLET

Q: What are the uses of AMLOACT AT TABLET?

A: AMLOACT AT TABLET is used to manage hypertension (also known as high blood
pressure) and angina pectoris (chest pain caused by a lack of oxygen supply to
the heart). By controlling blood pressure and improving oxygen supply to the
heart, this medicine can also contribute to protect your heart from heart
failure if you are suffering from previous history of heart attack.

Q: What type of medicine is AMLOACT AT TABLET?

A: AMLOACT AT TABLET is an antihypertensive medicine. Atenolol blocks the
effects of certain hormones (adrenaline) in the body that naturally increase
heart rate. This slows down the heartbeat and makes the heart pump blood with
less force. Amlodipine is a vasodilator. It relaxes the blood vessels supplying
the heart, which improves blood flow and oxygen supply to the heart muscles.
Collectively, they reduce the strain on the heart and improve heart function.

Q: How do I take AMLOACT AT TABLET?

A: Take AMLOACT AT TABLET as advised by your physician. Swallow the medicines
with a glass of water. Do not crush or chew the medicine. AMLOACT AT TABLET can
be taken with or without meals. Your doctor will decide the correct dose and
duration for you depending on your age, body weight, and disease condition.
Continue to take AMLOACT AT TABLET for the stipulated duration instructed by
your doctor to achieve better results.

Q: What should I do if I forget to take a dose of AMLOACT AT TABLET?

A: If you have missed a dose of AMLOACT AT TABLET, take it as soon as you
remember. However, if it is time for the next dose of AMLOACT AT TABLET, skip
the missed dose and take the next one regularly. Do not take a double dose of
AMLOACT AT TABLET to compensate for the missed ones.

Q: What precautions should be followed while taking AMLOACT AT TABLET?

A: Before taking AMLOACT AT TABLET, inform your doctor if you have any liver or
kidney problems. You must also inform your doctor if you have severe high or low
blood pressure or other heart problems (such as narrowing of the arteries,
cardiogenic shock, or a recent heart attack). Consult your doctor before taking
AMLOACT AT TABLET if you are pregnant and breastfeeding. Regularly visit your
doctor and take all the necessary blood tests recommended by your doctor without
fail.

Q: Can I consume alcohol while taking AMLOACT AT TABLET?

A: Avoid consum
you feel dizzy.

Q: What happens if I accidentally take more AMLOACT AT TABLET?

A: If you or anyone else accidentally took more AMLOACT AT TABLET, consult your
doctor immediately. Symptoms of overdosage might include dizziness, fainting,
light-headedness, weakness, shock, cool or clampy skin, and shortness of breath.

Q: Can AMLOACT AT TABLET cause ankle swelling?

A: AMLOACT AT TABLET may cause edema or swelling of the ankles in a few
patients. If you experience ankle swelling, keep your legs on a table or
slightly elevated from ground level. If this symptom bothers you, contact your
doctor.

Q: What are the side effects of AMLOACT AT TABLET?

A: The most common side effects of taking AMLOACT AT TABLET are swelling of
ankles or other body parts, headache, dizziness, sleepiness, tiredness, racing
heartbeat, indigestion, constipation, muscle cramps, cold hands and feet, and a
slow heartbeat. Contact your doctor if any of these side effects trouble you.

Q: Can I stop taking AMLOACT AT TABLET suddenly?

A: No. Do not stop taking AMLOACT AT TABLET without consulting your doctor. As
hypertension is a chronic condition, long term management may be necessary to
control its symptoms. Therefore, take AMLOACT AT TABLET as advised by your
doctor for the stipulated duration. Premature discontinuation of therapy may
increase your blood pressure once again.

Q: Can AMLOACT AT TABLET be taken during pregnancy?

A: AMLOACT AT TABLET should be used in pregnant women only if it is considered
necessary by the physician. Therefore, consult your doctor before taking it.

Q: Can AMLOACT AT TABLET be taken during breastfeeding?

A: AMLOACT AT TABLET should be used with caution in breastfeeding women as it
may pass through the breast milk to the nursing infant. Therefore, consult your
doctor before taking it.

Q: Can I take other medicines with AMLOACT AT TABLET?

A: Before taking AMLOACT AT TABLET, inform your doctor if you are taking, have
taken, or might take any other medicine, including prescri
non-prescri
other and cause serious side effects.

Q: Can the use of AMLOACT AT TABLET affect the liver?

A: Yes. AMLOACT AT TABLET should be used with caution in patients with liver
problems. Consult your doctor before taking it.

Q: Can AMLOACT AT TABLET cause erectile dysfunction?

A: AMLOACT AT TABLET may cause problems in erection in a few individuals.
Consult your doctor if it bothers you.

Q: Is AMLOACT AT TABLET safe to use in patients with heart problems?

A: AMLOACT AT TABLET is not recommended for use in patients with severe heart
problems such as heart failure, aortic stenosis (narrowing of arteries), or
cardiogenic shock (inability of the heart to pump blood). It should be used with
caution in patients with a history of recent heart attacks or heart failure.
Therefore, consult your doctor before taking it.

Useful Diagnostic Tests

• Kidney function test
• Cardiac Risk Profile